Hongjin Li
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View article: Pyramidal lens enables mesoscale structured illumination by surpassing the spatial bandwidth limit of spatial light modulators
Pyramidal lens enables mesoscale structured illumination by surpassing the spatial bandwidth limit of spatial light modulators Open
Structured illumination has emerged as a pivotal technique in biomedical imaging and machine vision, driving breakthroughs in optical sectioning, super-resolution microscopy, phase imaging, and 3D surface profiling. These applications rely…
View article: Exploring the respiratory viral landscape beyond influenza and SARS-CoV-2: a 2020–2023 study in Fujian, China
Exploring the respiratory viral landscape beyond influenza and SARS-CoV-2: a 2020–2023 study in Fujian, China Open
Introduction In this study, we investigated the local epidemiology and pathogen spectrum of acute respiratory infections caused by common respiratory viruses other than influenza virus (IFV) and severe acute respiratory syndrome coronaviru…
View article: The clinical risk and post-COVID-19 sequelae in patients with myasthenia gravis: a retrospective observational study
The clinical risk and post-COVID-19 sequelae in patients with myasthenia gravis: a retrospective observational study Open
Background There are indeed several studies addressing the severity of Coronavirus disease 2019 (COVID-19) infection in myasthenia gravis (MG) patients. However, data on post-COVID-19 sequelae in MG patients remain limited. To address this…
View article: Machine learning-based exploration of the associations between multiple minerals' intake and thyroid dysfunction: data from the National Health and Nutrition Examination Survey
Machine learning-based exploration of the associations between multiple minerals' intake and thyroid dysfunction: data from the National Health and Nutrition Examination Survey Open
Objectives The associations between various minerals' intake and thyroid dysfunction (TD), including hyperthyroidism and hypothyroidism, are still inconclusive, which may be attributed to the potential synergistic effects among various min…
View article: Feasibility and Acceptability of Integrating Acupuncture for Management of Multiple Symptoms in Medically Underserved Breast Cancer Survivors
Feasibility and Acceptability of Integrating Acupuncture for Management of Multiple Symptoms in Medically Underserved Breast Cancer Survivors Open
Background/Objectives: Breast cancer survivors undergoing long-term endocrine therapy often experience multiple symptoms, including pain, fatigue, sleep disturbance, hot flashes, anxiety, and depression. This study explored the feasibility…
View article: Using Serum Metabolomic Signatures to Investigate Effects of Acupuncture on Pain-Fatigue-Sleep Disturbance in Breast Cancer Survivors
Using Serum Metabolomic Signatures to Investigate Effects of Acupuncture on Pain-Fatigue-Sleep Disturbance in Breast Cancer Survivors Open
Background/Objectives: Acupuncture is an efficacious integrative therapy for treating pain, fatigue, and sleep disturbance (the psychoneurological symptom cluster) in breast cancer survivors. However, the mechanisms underlying its effects …
View article: Impacts of High Temperatures on the Growth and Development of Rice and Measures for Heat Tolerance Regulation: A Review
Impacts of High Temperatures on the Growth and Development of Rice and Measures for Heat Tolerance Regulation: A Review Open
As one of the world’s principal food crops, rice sustains over half of the global population. With global climate change intensifying, the frequency of extreme high temperatures is increasing, posing significant threats to the growth and d…
View article: Impact of Acupuncture on Human Metabolomic Profiles: A Systematic Review
Impact of Acupuncture on Human Metabolomic Profiles: A Systematic Review Open
Background/Objectives: Metabolomics provides insights into the biological underpinnings of disease development and treatment. This systematic review investigated the impact of acupuncture on metabolite levels and associated metabolic pathw…
View article: A thematic content analysis of the structure and effects of good doctor abilities in China
A thematic content analysis of the structure and effects of good doctor abilities in China Open
Background The efforts to explore and build the structure of good doctor abilities are important because they help improve the quality of education for medical students and better standardize the working performance of doctors. However, at…
View article: Case report: A highly active refractory myasthenia gravis with treatment of telitacicept combined with efgartigimod
Case report: A highly active refractory myasthenia gravis with treatment of telitacicept combined with efgartigimod Open
There is always a lack of effective treatment for highly active refractory generalized myasthenia gravis (GMG). Recently, telitacicept combined with efgartigimod significantly reduces circulating B cells, plasma cells, and immunoglobulin G…
View article: Exploration of the factors influencing the quality of life among adolescents during the COVID-19 pandemic: the data from a cross-sectional study in Shandong
Exploration of the factors influencing the quality of life among adolescents during the COVID-19 pandemic: the data from a cross-sectional study in Shandong Open
View article: Feasibility of implementing acupuncture in medically underserved breast cancer survivors (FAB): A protocol
Feasibility of implementing acupuncture in medically underserved breast cancer survivors (FAB): A protocol Open
View article: Monitoring and responding to signals of suicidal ideation in pragmatic clinical trials: Lessons from the GRACE trial for Chronic Sickle Cell Disease Pain
Monitoring and responding to signals of suicidal ideation in pragmatic clinical trials: Lessons from the GRACE trial for Chronic Sickle Cell Disease Pain Open
View article: Developing an Implementation Blueprint for the NIH HEAL Initiative GRACE Trial: Perspectives on Acupuncture and Guided Relaxation for Chronic Sickle Cell Disease Pain
Developing an Implementation Blueprint for the NIH HEAL Initiative GRACE Trial: Perspectives on Acupuncture and Guided Relaxation for Chronic Sickle Cell Disease Pain Open
Objective: This study aimed to explore perspectives of people living with sickle cell disease (SCD) and SCD clinic providers and staff about the use of acupuncture and guided relaxation for treating chronic SCD pain. Data obt…
View article: Outcome and clinical features in juvenile myasthenia gravis: A systematic review and meta-analysis
Outcome and clinical features in juvenile myasthenia gravis: A systematic review and meta-analysis Open
Background Juvenile myasthenia gravis (JMG) is a rare autoimmune disease that has so far only been described in small cohort studies. We defined the clinical characteristics, management, and outcomes of JMG patients over the past 22 years.…
View article: Hybrid effectiveness-implementation trial of guided relaxation and acupuncture for chronic sickle cell disease pain (GRACE): A protocol
Hybrid effectiveness-implementation trial of guided relaxation and acupuncture for chronic sickle cell disease pain (GRACE): A protocol Open
View article: Detection of Characteristic Waves in Clinical Visual Evoked Potential Signals Based on Deep Learning
Detection of Characteristic Waves in Clinical Visual Evoked Potential Signals Based on Deep Learning Open
View article: Evaluation and Treatment of Vulvodynia: State of the Science
Evaluation and Treatment of Vulvodynia: State of the Science Open
Vulvodynia affects 7% of American women, yet clinicians often lack awareness of its presentation. It is underdiagnosed and often misdiagnosed as vaginitis. The etiology of vulvodynia remains unknown, making it difficult to identify or deve…
View article: Feasibility of Acupuncture and Exploration of Metabolomic Alterations for Psychoneurological Symptoms Among Breast Cancer Survivors
Feasibility of Acupuncture and Exploration of Metabolomic Alterations for Psychoneurological Symptoms Among Breast Cancer Survivors Open
Objective Approximately 24–68% of breast cancer survivors report co-occurring psychoneurological symptoms of pain, fatigue, sleep disturbance, depression, and anxiety during and after cancer treatment. This study aimed to assess the feasib…
View article: Similarities and differences between SUNCT and SUNA: a cross-sectional, multicentre study of 76 patients in China
Similarities and differences between SUNCT and SUNA: a cross-sectional, multicentre study of 76 patients in China Open
View article: Tryptophan and Kynurenine Pathway Metabolites and Psychoneurological Symptoms Among Breast Cancer Survivors
Tryptophan and Kynurenine Pathway Metabolites and Psychoneurological Symptoms Among Breast Cancer Survivors Open
View article: A Genome-Wide Association Study of Prediabetes Status Change
A Genome-Wide Association Study of Prediabetes Status Change Open
We conducted the first genome-wide association study of prediabetes status change (to diabetes or normal glycaemia) among 900 White participants of the Atherosclerosis Risk in Communities (ARIC) study. Single nucleotide polymorphism (SNP)-…
View article: Sphingosine-1-Phosphate and Its Signal Modulators Alleviate Psoriasis-Like Dermatitis: Preclinical and Clinical Evidence and Possible Mechanisms
Sphingosine-1-Phosphate and Its Signal Modulators Alleviate Psoriasis-Like Dermatitis: Preclinical and Clinical Evidence and Possible Mechanisms Open
Background Psoriasis is an autoimmune skin disease associated with lipid metabolism. Sphingosine-1-phosphate (S1P) is a bioactive lipid that plays a key role in the development of autoimmune diseases. However, there is currently a lack of …
View article: DAKS1, a Kunitz Scaffold Peptide from the Venom Gland of Deinagkistrodon acutus Prevents Carotid-Artery and Middle-Cerebral-Artery Thrombosis via Targeting Factor XIa
DAKS1, a Kunitz Scaffold Peptide from the Venom Gland of Deinagkistrodon acutus Prevents Carotid-Artery and Middle-Cerebral-Artery Thrombosis via Targeting Factor XIa Open
Scaffold-based peptides (SBPs) are fragments of large proteins that are characterized by potent bioactivity, high thermostability, and low immunogenicity. Some SBPs have been approved by the FDA for human use. In the present study, we deve…
View article: Symptom Clusters in Head and Neck Cancer: A Systematic Review and Conceptual Model
Symptom Clusters in Head and Neck Cancer: A Systematic Review and Conceptual Model Open
View article: Acupuncture Improves Multiple Treatment-Related Symptoms in Breast Cancer Survivors: A Systematic Review and Meta-Analysis
Acupuncture Improves Multiple Treatment-Related Symptoms in Breast Cancer Survivors: A Systematic Review and Meta-Analysis Open
Introduction: Acupuncture has demonstrated effectiveness for symptom management among breast cancer survivors. This meta-analysis aims to evaluate the effect of acupuncture on treatment-related symptoms among breast cancer su…
View article: Updated Evidence of the Association Between Elevated Serum Uric Acid Level and Psoriasis
Updated Evidence of the Association Between Elevated Serum Uric Acid Level and Psoriasis Open
Background: Our earlier meta-analysis showed that the correlation between psoriasis and hyperuricemia might be region-dependent and that hyperuricemia was more common in patients with psoriasis in Western Europe. However, no further analys…
View article: Acupuncture for chronic pain in adults with sickle cell disease: a mixed-methods pilot study
Acupuncture for chronic pain in adults with sickle cell disease: a mixed-methods pilot study Open
Objective: Chronic pain is a common symptom experienced among patients with sickle cell disease (SCD). Our aims were to assess the feasibility and acceptability of performing acupuncture for the treatment of chronic pain in adults with SCD…
View article: Pattern of Cumulative Treatment Hours on Pain Impact and PROMIS Outcomes
Pattern of Cumulative Treatment Hours on Pain Impact and PROMIS Outcomes Open
Introduction Participation in interdisciplinary treatments is associated with improvement in pain intensity, physical function, and additional pain-related outcome domains. However, the effect of cumulative treatment hours on outcomes rema…
View article: Relationship Between Post-Traumatic Stress Disorder Symptoms and Chronic Pain-Related Symptom Domains Among Military Active Duty Service Members
Relationship Between Post-Traumatic Stress Disorder Symptoms and Chronic Pain-Related Symptom Domains Among Military Active Duty Service Members Open
Objective This study examined the relationships between symptom domains relevant to post-traumatic stress disorder (PTSD) diagnosis, PTSD screening, and chronic pain-related symptoms (pain intensity, pain interference, physical function, f…