Explanipedia

Application of nanobody‑based CAR‑T in tumor immunotherapy (Review) Open

Hongjing Liu, Xueping Liu, Xuyan Zhou, Siliang Duan, Xin Huang , et al. · 2025

Chimeric antigen receptor (CAR) T cell therapy is a type of cellular immunotherapy showing promising clinical effectiveness and high precision. CAR‑T cells express membrane receptors with high specificity, which enable them to identify cer…

Double-End Location Technology of Partial Discharge in Cables Based on Frequency-Domain Reflectometry Open

Miao Wang, Hongjing Liu, Ci Song, Hongda Li, Nan He , et al. · 2025

To realize the region determination and accurate location of cable partial discharge, this paper proposes a cable partial discharge double-end location technique based on frequency-domain reflectometry. The cable partial discharge double-e…

Tumor-targeting bioluminescent bacteria for in vivo imaging Open

Chenghao Ma, Jingxi Liu, Hongjing Liu, Xiaohan Zhao, Geng Li , et al. · 2025

Research Progress on Varicella-Zoster Virus Vaccines Open

Hongjing Liu, Lingyan Cui, Sibo Zhang, Hong Wang, Wenhui Xue , et al. · 2025

Varicella-zoster virus (VZV) poses significant public health challenges as the etiological agent of varicella (chickenpox) and herpes zoster (HZ), given its high transmissibility and potential for severe complications. The introduction of …

Surface charge transfer adjustment from designing thin-layer structure targeted O2 adsorption and activation for deep NO oxidation on Bi2MoO6 Open

Hongjing Liu, Shan Ren, Xiaodi Li, Liang Wang, Bofeng Bai , et al. · 2025

Design of an Ultra-High-Frequency Through-Core Current Transformer for Cable Partial Discharge Detection Open

Hongjing Liu, Hongda Li, Nan He, Jingzhu Teng, Baoqin Cao , et al. · 2025

Aiming at the problem of the through-core current sensor based on cable partial discharge detection having difficulty in compatibility with high sensitivity and wide detection frequency band, this paper proposes a design method for an ultr…

Immunogenicity and cellular response of a herpes zoster virus gEgI fusion protein adjuvanted with CpG-emulsion in mice Open

Sibo Zhang, Yarong Zeng, Lingyan Cui, Yiwen Zhang, Tingting Chen , et al. · 2025

Epigoitrin ameliorates acute liver injury in mice via regulation of the TLR4/NF-κB signaling pathway Open

Mingli Zhuge, Hongjing Liu, Lang Qin, Guanghui Wang, Xueping Liu · 2025

Background Acute liver injury (ALI), frequently triggered by drugs, toxins, or viral infections, is closely associated with the aberrant activation of the TLR4/NF-κB signaling pathway. Epigoitrin (EPG), a major bioactive component derived …

Glycoprotein E-Displaying Nanoparticles Induce Robust Neutralizing Antibodies and T-Cell Response against Varicella Zoster Virus Open

Hong Wang, Sibo Zhang, Wenhui Xue, Yarong Zeng, Liqin Liu , et al. · 2024

The Varicella zoster virus (VZV), responsible for both varicella (chickenpox) and herpes zoster (shingles), presents significant global health challenges. While primary VZV infection primarily affects children, leading to chickenpox, react…

Comprehensive Overview of Broadly Neutralizing Antibodies against SARS-CoV-2 Variants Open

Lingyan Cui, Tingting Li, Wenhui Xue, Sibo Zhang, Hong Wang , et al. · 2024

Currently, SARS-CoV-2 has evolved into various variants, including the numerous highly mutated Omicron sub-lineages, significantly increasing immune evasion ability. The development raises concerns about the possibly diminished effectivene…

Comprehensive Overview of Broadly Neutralizing Antibodies against SARS-COV-2 Variants Open

Lingyan Cui, Tingting Li, Wenhui Xue, Sibo Zhang, Hong Wang , et al. · 2024

Currently, SARS-CoV-2 has evolved into various variants, including the numerous highly mutated Omicron sub-lineages, significantly increasing immune evasion ability. The development raises concerns about possibly diminished effectiveness o…

Cancer-associated fibroblast-derived extracellular vesicles promote lymph node metastases in oral cavity squamous cell carcinoma by encapsulating ITGB1 and BMI1 Open

Tianzhu Lv, Hongjing Liu, Ling Mao, Yanrong Song, Lili Liao , et al. · 2024

Background Extracellular vesicles (EVs) have been revealed to facilitate the development of oral squamous cavity cell carcinoma (OCSCC), while its supporting role in lymph node metastases is under continuous investigation. This study aimed…

Synergistic Improvement in Gas Separation Performance of Mmms by Porogenic Action and Strong Molecular Forces of Zif-93 Open

Ding Yaping, Yan Dai, Huahao Wang, Xiaochen Yang, Miao Yu , et al. · 2024

Multi-frequency piezoelectric vibration energy harvesters powered sensing in power grid transformer Open

Lu Wang, Congsheng Duan, Chunlong Li, Qian Wang, Hui Huang , et al. · 2024

With the development of smart grid, many wireless sensor nodes (WSN) used in monitoring grid equipment need continuous power supply. This work propose a multi-frequency array piezoelectric vibration energy harvester (PVEH) powering WSN bas…

Additional file 1 of Cancer-associated fibroblast-derived extracellular vesicles promote lymph node metastases in oral cavity squamous cell carcinoma by encapsulating ITGB1 and BMI1 Open

Tianzhu Lv, Hongjing Liu, Ling Mao, Yanrong Song, Lili Liao , et al. · 2024

Supplementary Material 1

Developing Advanced Oxygen Electrodes for Reversible Protonic Ceramic Electrochemical Cells Via Controlled Bismuth Doping on Diverse Perovskite Lattice Positions Open

Yushi Feng, Peng Su, Hongjing Liu, Xu Sun, Bin Zhang , et al. · 2024

The Influence of Ferroelectric Dipoles on the Output Performance of Triboelectric Nanogenerator Open

Chunlong Li, Hui Huang, Dengfeng Ju, Hongjing Liu, Kewen Liu , et al. · 2023

A method based on ferroelectric dipole to enhance surface charge density of triboelectric generator was proposed. By using the ferroelectric properties of polyvinylidene fluoride (PVDF), a positive charge trap was formed in the triboelectr…

Multi-Functionalized Mcns Effectively Improve the Interfacial Compatibility of Mixed Matrix Membranes and Enhance Co2 Separation Performance Open

Huahao Wang, Xiaochen Yang, Yan Dai, Miao Yu, Wenji Zheng , et al. · 2023

Effects of Shenling Baizhu powder on pyrotinib-induced diarrhea: analysis of gut microbiota, metabonomics, and network pharmacology Open

Jingjiang Lai, Fengxian Jiang, Xiaoli Zhuo, Xiaoying Xu, Lei Liu , et al. · 2022

Frequency Modulation Approach for High Power Density 100 Hz Piezoelectric Vibration Energy Harvester Open

Dengfeng Ju, Lu Wang, Chunlong Li, Hui Huang, Hongjing Liu , et al. · 2022

Piezoelectric vibration energy harvester (PVEH) is a promising device for sustainable power supply of wireless sensor nodes (WSNs). PVEH is resonant and generates power under constant frequency vibration excitation of mechanical equipment.…

Effects of Shenling Baizhu Powder on Pyrotinib-Induced Diarrhea: Analysis of Gut Microbiota, Metabonomics, and Network Pharmacology Open

Jingjiang Lai, Fengxian Jiang, Xiaoli Zhuo, Xiaoying Xu, Lei Liu , et al. · 2022

Background Shenling Baizhu Powder (SBP) is a traditional Chinese medicine (TCM) prescription, which has good efficacy on gastrointestinal toxicity. In this study, we used gut microbiota analysis, metabonomics, and network pharmacology to i…

Effect of muscle distribution and fat distribution on standing long jump in young adults Open

Wenbo Shu, Chunyan Li, Peng Liu, Zheng-yi Xie, Yu Luo , et al. · 2022

Background Standing long jump is the most reliable method to test the explosive power of lower limbs, and research on its relationship with body composition may be of significance to public health. Objective To study the effect of muscle d…

Discovery of non-substrate, environmentally sensitive turn-on fluorescent probes for imaging HDAC8 in tumor cells and tissue slices Open

Chaoqun Huang, Yi Shu, Yueyue Zhu, Hongjing Liu, Xinzhi Wang , et al. · 2022

Effect of Curing Agent Dosage on Fire Resistance of Waterborne Epoxy Coating Open

Jingyi Wang, Rongrong Zheng, Xingwei Li, Hongjing Liu, Liyan Wang · 2022

The water-based epoxy fire retardant coating is formed by reaction curing, which not only has good anti-corrosion performance, but also has environmental protection and flame retardant performance, which is suitable for construction machin…

Knockdown of lncRNA DLEU1 inhibits the tumorigenesis of oral squamous cell carcinoma via regulation of miR‑149‑5p/CDK6 axis Open

Tianzhu Lv, Hongjing Liu, Yadong Wu, Wentao Huang · 2021

Oral squamous cell carcinoma (OSCC) is a frequent malignant tumor worldwide. Long non‑coding RNAs (lncRNAs) are known to play key roles in different types of cancer, including OSCC. It was previously reported that lncRNA deleted in lymphoc…

Generation of dual functional nanobody-nanoluciferase fusion and its potential in bioluminescence enzyme immunoassay for trace glypican-3 in serum Open

Sheng Yü, Zhenfeng Li, Jingzhang Li, Shimei Zhao, Shanguang Wu , et al. · 2021

Nanobodies targeting immune checkpoint molecules for tumor immunotherapy and immunoimaging (Review) Open

Sheng Yü, Xiong Gui, Shimei Zhao, Yanbo Tang, Hua Tang , et al. · 2020

The immune checkpoint blockade is an effective strategy to enhance the anti‑tumor T cell effector activity, thus becoming one of the most promising immunotherapeutic strategies in the history of cancer treatment. Several immune checkpoint …

Bi‐based photocatalysts for <span>light‐driven</span> environmental and energy applications: Structural tuning, reaction mechanisms, and challenges Open

Peng Chen, Hongjing Liu, Wen Cui, Shuncheng Lee, Wang Liao , et al. · 2020

Environmental pollution and energy crisis have become major challenges to sustainable development of human society. Solar‐driven photocatalytic technology is regarded as an extremely attractive solution to environmental remediation and ene…

Big data-based applied research on hazardous chemical safety regulation Open

Ya Ban, Hongjing Liu, Tianhao Fei, Hao Luo, Ling Yu , et al. · 2020

With the rapid development of modern industry in China, a large number of hazardous chemicals are put into the production and use of chemical enterprises, increasing the probability of hazardous chemical accidents to a certain extent. Beca…

Design and implementation of forecast and early warning system for offshore platform based on GIS Open

Ya Ban, Hongjing Liu, Hongying Liu, Fan Yang, Jing Yuan · 2019

A forecast and early warning system for offshore platform was developed to reduce security risks of offshore operations. The tool uses an ArcGIS Server as electronic chart display and system platform, in combination with Silverlight, WCF S…

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