Hongxian Zhang
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View article: Urothelial carcinoma following kidney transplantation: a narrative review of Chinese insights and challenges from pathogenesis to precision diagnosis and treatment
Urothelial carcinoma following kidney transplantation: a narrative review of Chinese insights and challenges from pathogenesis to precision diagnosis and treatment Open
Kidney transplant recipients (KTRs) exhibit a higher incidence of neoplasms compared to the general population, primarily due to the prolonged administration of immunosuppressive agents and viral infections. In China, the primary type of t…
View article: Risk Factors and Metastasis Prediction in Small (≤4 cm) Clear Cell Renal Cell Carcinoma: A Nested Case-Control Study
Risk Factors and Metastasis Prediction in Small (≤4 cm) Clear Cell Renal Cell Carcinoma: A Nested Case-Control Study Open
Purpose To investigate the clinicopathological factors affecting the metastasis and prognosis in small clear cell renal carcinoma (ccRCC) (≤ 4 cm), so as to guide clinical management and follow-up. Methods This study retrospectively analyz…
View article: Global burden of chronic kidney disease in adults aged 60 years and older, 1990-2021 and projections to 2050: an analysis of the global burden of disease study 2021
Global burden of chronic kidney disease in adults aged 60 years and older, 1990-2021 and projections to 2050: an analysis of the global burden of disease study 2021 Open
Background Chronic kidney disease (CKD) represents a significant global public health challenge and is often underestimated in those over 60. Understanding its impact on the elderly individuals is crucial for proper healthcare resource all…
View article: Imaging classification and surgical strategy of retroperitoneal vascular leiomyosarcoma: experience from a single medical center
Imaging classification and surgical strategy of retroperitoneal vascular leiomyosarcoma: experience from a single medical center Open
View article: Flotation Behaviours of Ilmenite and Associated Solution Chemistry Properties Using Saturated Fatty Acids as the Collector
Flotation Behaviours of Ilmenite and Associated Solution Chemistry Properties Using Saturated Fatty Acids as the Collector Open
A series of homologous saturated fatty acids were introduced and evaluated as collectors for ilmenite flotation using a combination of micro-flotation tests and surface tension measurements. The results showed that ilmenite exhibited good …
View article: Exploring the Therapeutic Mechanism of Jianpi Zhidong Decoction on Tourette Syndrome Based on Proteomics and Network Pharmacology
Exploring the Therapeutic Mechanism of Jianpi Zhidong Decoction on Tourette Syndrome Based on Proteomics and Network Pharmacology Open
JPZDD (16 g·kg⁻¹·d⁻¹) alleviates motor tics, modulates microglial activation and glucose metabolism, and downregulates the PI3K/AKT/mTOR pathway, providing a mechanistic basis for its therapeutic role in TS.
View article: Key Factors and Configuration Analysis of Improving Tourist Loyalty in Forest Park: Evidence from Yingde National Forest Park, South China
Key Factors and Configuration Analysis of Improving Tourist Loyalty in Forest Park: Evidence from Yingde National Forest Park, South China Open
Tourist perceived value is an important antecedent to loyalty by enhancing satisfaction, revisiting intentions, and recommendations, thereby promoting sustainable development of forest parks. However, existing research has not sufficiently…
View article: Risk factors for renal insufficiency and survival implications after radical nephrectomy and thrombectomy in renal cell carcinoma with tumor thrombus: a systematic review
Risk factors for renal insufficiency and survival implications after radical nephrectomy and thrombectomy in renal cell carcinoma with tumor thrombus: a systematic review Open
View article: Risk factors for lymphatic leakage following radical cystectomy and pelvic lymph node dissection in patients with muscle-invasive bladder cancer
Risk factors for lymphatic leakage following radical cystectomy and pelvic lymph node dissection in patients with muscle-invasive bladder cancer Open
The increased number of dissected lymph nodes is associated with a heightened risk of lymphatic leakage following radical cystectomy for MIBC.
View article: Risk Factors for Lymphatic Leakage Following Radical Cystectomy and Pelvic Lymph Node Dissection in Patients with Muscle-Invasive Bladder Cancer
Risk Factors for Lymphatic Leakage Following Radical Cystectomy and Pelvic Lymph Node Dissection in Patients with Muscle-Invasive Bladder Cancer Open
Background Lymphatic leakage is a common complication after radical cystectomy and pelvic lymph node dissection (PLND) for muscle-invasive bladder cancer (MIBC).This study aimed to investigate the risk factors contributing to postoperative…
View article: Robot-assisted radical nephroureterectomy using the KangDuo Surgical Robot-01 System versus the da Vinci System: a multicenter prospective randomized controlled trial
Robot-assisted radical nephroureterectomy using the KangDuo Surgical Robot-01 System versus the da Vinci System: a multicenter prospective randomized controlled trial Open
The KD-SR-01 system is safe and effective for RARNU compared to the DV Si or Xi system. Further randomized controlled studies with larger sample sizes and longer durations are required.
View article: [Predicting the 3-year tumor-specific survival in patients with T<sub>3a</sub> non-metastatic renal cell carcinoma].
[Predicting the 3-year tumor-specific survival in patients with T<sub>3a</sub> non-metastatic renal cell carcinoma]. Open
A nomogram model predicting the 3-year CSS of non-metastatic T3a renal cell carcinoma patients was successfully constructed and validated in this study. This nomogram can assist clinicians in accurately assessing the long-term p…
View article: [Functional and oncologic outcomes of partial nephrectomy for cystic renal cell carcinoma: A single-center retrospective study].
[Functional and oncologic outcomes of partial nephrectomy for cystic renal cell carcinoma: A single-center retrospective study]. Open
Partial nephrectomy for cystic renal cell carcinoma is safe and feasible with favorable renal function and oncologic outcomes.
View article: Influence of tumor thrombus morphology on the surgical complexity in renal cell carcinoma with inferior vena cava tumor thrombus: a single-center, large-sample study from China
Influence of tumor thrombus morphology on the surgical complexity in renal cell carcinoma with inferior vena cava tumor thrombus: a single-center, large-sample study from China Open
Background The morphology of tumor thrombus varies from person to person and it may affect surgical methods and tumor prognosis. However, studies on the morphology of tumor thrombus are limited. The purpose of our study was to evaluate the…
View article: Risk factors for renal insufficiency after radical nephrectomy and thrombectomy in renal cell carcinoma with tumor thrombus: A systematic review
Risk factors for renal insufficiency after radical nephrectomy and thrombectomy in renal cell carcinoma with tumor thrombus: A systematic review Open
Background: Renal cell carcinoma (RCC) with venous tumor thrombus (VTT) is great burden over world. Radical nephrectomy (RN) with thrombectomy seems to be its gold standard operation, which might cause reduction of renal function. The aim …
View article: [Discussion on the surgical timing of rupture and hemorrhage of renal angiomyolipoma].
[Discussion on the surgical timing of rupture and hemorrhage of renal angiomyolipoma]. Open
We believe that for patients with RAML rupture and hemorrhage, reoperation for more than 6 months is a relatively safe time range, with minimal intraoperative bleeding. Therefore, it is more recommended to undergo surgical treatment after …
View article: Neoadjuvant stereotactic ablative body radiotherapy combined with surgical treatment for renal cell carcinoma and inferior vena cava tumor thrombus: a prospective pilot study
Neoadjuvant stereotactic ablative body radiotherapy combined with surgical treatment for renal cell carcinoma and inferior vena cava tumor thrombus: a prospective pilot study Open
Background Surgical treatment for renal cell carcinoma (RCC) and inferior vena cava (IVC) tumor thrombus (TT) is difficult, and the postoperative complication rate is high. This study aimed to explore the safety and oncologic outcomes of n…
View article: Prevention, incidence, and risk factors of chyle leak after radical nephrectomy and thrombectomy
Prevention, incidence, and risk factors of chyle leak after radical nephrectomy and thrombectomy Open
Background To define the incidence and risk factors of chyle leak (CL) after radical nephrectomy and thrombectomy and to determine the impact of chyle leak on oncological outcomes. Patients and Methods A total of 445 patients who underwent…
View article: Neoadjuvant Stereotactic Ablative Body Radiotherapy Combined with Surgical Treatment for Renal Cell Carcinoma and Inferior Vena Cava Tumor Thrombus: A Prospective Pilot Study
Neoadjuvant Stereotactic Ablative Body Radiotherapy Combined with Surgical Treatment for Renal Cell Carcinoma and Inferior Vena Cava Tumor Thrombus: A Prospective Pilot Study Open
Background Surgical treatment for renal cell carcinoma (RCC) and inferior vena cava (IVC) tumor thrombus (TT) is difficult and has a high postoperative complication rate. This study aims to explore the safety and oncologic outcomes of neoa…
View article: Critical role of VHL/BICD2/STAT1 axis in crystal-associated kidney disease
Critical role of VHL/BICD2/STAT1 axis in crystal-associated kidney disease Open
View article: Long-term survival after female pelvic organ-sparing radical cystectomy versus standard radical cystectomy: a multi-institutional propensity score-matched analysis
Long-term survival after female pelvic organ-sparing radical cystectomy versus standard radical cystectomy: a multi-institutional propensity score-matched analysis Open
Background: The application of pelvic organ preserving-radical cystectomy (POPRC) in female patients with bladder cancer has attracted more and more attention in recent years. In the current study, the authors aim to compare the long-term …
View article: Long-term outcomes after cytoreductive nephrectomy and thrombectomy of patients with metastatic renal cell carcinoma with venous tumor thrombus: a retrospective study from a large Chinese center
Long-term outcomes after cytoreductive nephrectomy and thrombectomy of patients with metastatic renal cell carcinoma with venous tumor thrombus: a retrospective study from a large Chinese center Open
Background Targeted therapy combined with immunotherapy is the current first-line treatment for metastatic renal cell carcinoma (mRCC), but patients with tumor thrombus (TT) may suffer from lower limb edema or even sudden cardiac death, so…
View article: Cephalic inferior vena cava non-clamping technique versus standard procedure for robot-assisted laparoscopic level II–III thrombectomy: a prospective cohort study
Cephalic inferior vena cava non-clamping technique versus standard procedure for robot-assisted laparoscopic level II–III thrombectomy: a prospective cohort study Open
Background: Renal tumour can invade the venous system and ~4–10% patients with renal tumour had venous thrombus. Although the feasibility of robot-assisted laparoscopic inferior vena cava thrombectomy (RAL-IVCT) in patients with inferior v…
View article: Preliminary experience of oblique occlusion technique in robot-assisted infrahepatic inferior vena cava thrombectomy: step-by-step procedures and short term outcomes
Preliminary experience of oblique occlusion technique in robot-assisted infrahepatic inferior vena cava thrombectomy: step-by-step procedures and short term outcomes Open
View article: Efficacy and safety of Chinese herbal medicine for pneumonia convalescence in children: A systematic review and meta-analysis
Efficacy and safety of Chinese herbal medicine for pneumonia convalescence in children: A systematic review and meta-analysis Open
Background: Chinese herbal medicine (CHM) has advantages in treating sequela symptoms of pediatric pneumonia convalescence. Hence, this study aims to evaluate the efficacy and safety of CHM using a meta-analysis approach. Methods: The rand…
View article: Analysis of genetic profiling, pathomics signature, and prognostic features of primary lymphoepithelioma‐like carcinoma of the renal pelvis
Analysis of genetic profiling, pathomics signature, and prognostic features of primary lymphoepithelioma‐like carcinoma of the renal pelvis Open
The genetic features of primary lymphoepithelioma‐like carcinoma (LELC) of the upper urinary tract have not been systematically explored. In this study, tumor mutation profiling was performed using whole‐genome sequencing in two patients w…
View article: A “3S+f” Nephrometry Score System to Predict the Clinical Outcomes of Laparoscopic Nephron-Sparing Surgery
A “3S+f” Nephrometry Score System to Predict the Clinical Outcomes of Laparoscopic Nephron-Sparing Surgery Open
Background When we treat renal cell carcinoma by laparoscopic nephron-sparing surgery (NSS), it is essential to use an evaluation system to predict clinical outcomes. Hitherto, there are more than a dozen nephrometry score systems. In this…
View article: Clinical experience and treatment strategy of leiomyosarcoma originating from the renal vein
Clinical experience and treatment strategy of leiomyosarcoma originating from the renal vein Open
View article: T.H.R.O.B.V.S. Score – A Comprehensive Model to Predict the Surgical Complexity of Renal Cell Carcinoma With Tumor Thrombus
T.H.R.O.B.V.S. Score – A Comprehensive Model to Predict the Surgical Complexity of Renal Cell Carcinoma With Tumor Thrombus Open
Background To propose a quantitative model for predicting the surgical complexity of patients with renal cell carcinoma (RCC) and venous tumor thrombus (VTT). Method The clinical data of 226 cases of RCC with VTT in Peking University Third…
View article: Robot-Assisted Laparoscopic IVC Treatment Strategy in Retroperitoneal Tumors
Robot-Assisted Laparoscopic IVC Treatment Strategy in Retroperitoneal Tumors Open
Objectives To show the practice of robot-assisted laparoscopic inferior vena cava (IVC) treatment strategies in patients with retroperitoneal tumors. Patients and Methods From October 2020 to July 2021, 17 patients with retroperitoneal tum…