Hong‐Yu Ren
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View article: Genetic Evolution of H9N2 Avian Influenza Virus in Guangxi, China
Genetic Evolution of H9N2 Avian Influenza Virus in Guangxi, China Open
H9N2 avian influenza virus (AIV) is widely prevalent in poultry in China. To understand the genetic characteristics and evolution of H9N2 AIVs in Guangxi, southern China, the complete genomes of H9N2 AIVs from 1999–2023 were systematically…
View article: Current and Future Projection of Scrub Typhus Risk Related to Land Use Change in China
Current and Future Projection of Scrub Typhus Risk Related to Land Use Change in China Open
The widespread concern surrounding the enhanced spillover risk of infectious diseases due to dramatic global land use changes has sparked significant discussion. However, the specific implications of these changes on scrub typhus, a vector…
View article: Deliberative Alignment: Reasoning Enables Safer Language Models
Deliberative Alignment: Reasoning Enables Safer Language Models Open
As large-scale language models increasingly impact safety-critical domains, ensuring their reliable adherence to well-defined principles remains a fundamental challenge. We introduce Deliberative Alignment, a new paradigm that directly tea…
View article: Characterizing the epidemiology of <i>Mycoplasma pneumoniae</i> infections in China in 2022–2024: a nationwide cross-sectional study of over 1.6 million cases
Characterizing the epidemiology of <i>Mycoplasma pneumoniae</i> infections in China in 2022–2024: a nationwide cross-sectional study of over 1.6 million cases Open
Mycoplasma pneumoniae (MP) is a leading cause of community-acquired pneumonia (CAP), accounting for 10-40% of cases in children. In China, the high prevalence of macrolide-resistant MP (MRMP) and recurrent MP epidemics place a signi…
View article: Maliciously Secure Circuit Private Set Intersection via SPDZ-Compatible Oblivious PRF
Maliciously Secure Circuit Private Set Intersection via SPDZ-Compatible Oblivious PRF Open
Circuit Private Set Intersection (Circuit-PSI) allows two parties to compute a function f on items in the intersection of their input sets without revealing items in the intersection set. It is a well-known variant of PSI and has numerous …
View article: Multi-omics association pattern between gut microbiota and host metabolism of a filter-feeding fish in situ exposed to microplastics
Multi-omics association pattern between gut microbiota and host metabolism of a filter-feeding fish in situ exposed to microplastics Open
Microplastics (MPs) are widespread in water environments and can affect gut microbiota and host metabolism of fish, but whether changes in host metabolism under MPs are mediated by gut microbiota remains unclear. Here, silver carp, a filte…
View article: Advances in Green Energy, Environment and Carbon Neutralization
Advances in Green Energy, Environment and Carbon Neutralization Open
Population growth and industrialization have led to a rapid increase in the consumption of fossil fuels and resources [...]
View article: CCDC 2369162: Experimental Crystal Structure Determination
CCDC 2369162: Experimental Crystal Structure Determination Open
An entry from the Cambridge Structural Database, the world’s repository for small molecule crystal structures. The entry contains experimental data from a crystal diffraction study. The deposited dataset for this entry is freely available …
View article: Deliberative Alignment: Reasoning Enables Safer Language Models
Deliberative Alignment: Reasoning Enables Safer Language Models Open
As large-scale language models increasingly impact safety-critical domains, ensuring their reliable adherence to well-defined principles remains a fundamental challenge. We introduce Deliberative Alignment, a new paradigm that directly tea…
View article: Harnessing P450 enzyme plasticity for generalizable peptide biaryl macrocyclization
Harnessing P450 enzyme plasticity for generalizable peptide biaryl macrocyclization Open
Macrocyclic peptides containing biaryl motifs, predominantly derived from natural products, are valuable scaffolds due to their structural rigidity and potent bioactivity. However, current synthetic methods remain constrained by the absenc…
View article: Simultaneous differential detection of H5, H7 and H9 subtypes of avian influenza viruses by a triplex fluorescence loop-mediated isothermal amplification assay
Simultaneous differential detection of H5, H7 and H9 subtypes of avian influenza viruses by a triplex fluorescence loop-mediated isothermal amplification assay Open
H5, H7, and H9 are pivotal avian influenza virus (AIV) subtypes that cause substantial economic losses and pose potential threats to public health worldwide. In this study, a novel triplex fluorescence reverse transcription-loop-mediated i…
View article: Design and Evaluation of Novel Submerged Floating Tunnel Models Based on Dynamic Similarity
Design and Evaluation of Novel Submerged Floating Tunnel Models Based on Dynamic Similarity Open
Submerged floating tunnels (SFTs), also known as the Archimedes Bridge, are new transportation structures designed for crossing deep waters. Compared with cross-sea bridges and subsea tunnels, SFTs offer superior environmental adaptability…
View article: Biochar-based composites for removing chlorinated organic pollutants: Applications, mechanisms, and perspectives
Biochar-based composites for removing chlorinated organic pollutants: Applications, mechanisms, and perspectives Open
Chlorinated organic pollutants constitute a significant category of persistent organic pollutants due to their widespread presence in the environment, which is primarily attributed to the expansion of agricultural and industrial activities…
View article: Changes in Growth Parameters, C:N:P Stoichiometry and Non-Structural Carbohydrate Contents of Zanthoxylum armatum Seedling in Response to Five Soil Types
Changes in Growth Parameters, C:N:P Stoichiometry and Non-Structural Carbohydrate Contents of Zanthoxylum armatum Seedling in Response to Five Soil Types Open
Zanthoxylum armatum (Z. armatum) is an economic crop widely planted for both spice and medicinal purposes in Southwest China. Soil is a key environmental condition that affects seedling growth and development, and screening suitable soil t…
View article: Effect of metal insertion on the magnetic properties and anomalous Hall effect in MgO/CoFeB/Ta/MgO films
Effect of metal insertion on the magnetic properties and anomalous Hall effect in MgO/CoFeB/Ta/MgO films Open
CoFeB-based nano-magnetic multilayers can be applied in magnetic sensors, magnetic random access memory and other logic devices, which have attracted wide attention. The magnetic properties and interface structure of the magnetic multilaye…
View article: Analysis of Chicken IFITM3 Gene Expression and Its Effect on Avian Reovirus Replication
Analysis of Chicken IFITM3 Gene Expression and Its Effect on Avian Reovirus Replication Open
Interferon-inducible transmembrane protein 3 (IFITM3) is an antiviral factor that plays an important role in the host innate immune response against viruses. Previous studies have shown that IFITM3 is upregulated in various tissues and org…
View article: TimeGraphs: Graph-based Temporal Reasoning
TimeGraphs: Graph-based Temporal Reasoning Open
Many real-world systems exhibit temporal, dynamic behaviors, which are captured as time series of complex agent interactions. To perform temporal reasoning, current methods primarily encode temporal dynamics through simple sequence-based m…
View article: A sandwich amperometric immunosensor for the detection of fowl adenovirus group I based on bimetallic Pt/Ag nanoparticle-functionalized multiwalled carbon nanotubes
A sandwich amperometric immunosensor for the detection of fowl adenovirus group I based on bimetallic Pt/Ag nanoparticle-functionalized multiwalled carbon nanotubes Open
View article: Enhancing E. Coli Removal in Mesophilic Anaerobic Digestion: New Insights from Inoculum Comparison and Metagenomic Analysis
Enhancing E. Coli Removal in Mesophilic Anaerobic Digestion: New Insights from Inoculum Comparison and Metagenomic Analysis Open
View article: Process Exploration of Domestication, Start-Up and Rapid Recovery Strategies for Anaerobic Digestion of Sole Corn Stover: Methane Production Efficiency and Dominant Microbial Responses
Process Exploration of Domestication, Start-Up and Rapid Recovery Strategies for Anaerobic Digestion of Sole Corn Stover: Methane Production Efficiency and Dominant Microbial Responses Open
View article: Enhancing E. Coli Removal in Mesophilic Anaerobic Digestion: New Insights from Inoculum Comparison and Metagenomic Analysis
Enhancing E. Coli Removal in Mesophilic Anaerobic Digestion: New Insights from Inoculum Comparison and Metagenomic Analysis Open
View article: Ultrasonic Assisted Extraction of Phenolic Compounds from <i>Zanthoxylum Armatum</i> Leaves: Process Optimization, Characterization and Antioxidant Activity
Ultrasonic Assisted Extraction of Phenolic Compounds from <i>Zanthoxylum Armatum</i> Leaves: Process Optimization, Characterization and Antioxidant Activity Open
View article: Characterising the Epidemiology of Mycoplasma Pneumoniae Infections in China in 2022–2024: A Nationwide Cross-Sectional Study of Over 1.6 Million Cases
Characterising the Epidemiology of Mycoplasma Pneumoniae Infections in China in 2022–2024: A Nationwide Cross-Sectional Study of Over 1.6 Million Cases Open
View article: Process Exploration of Domestication, Start-Up and Rapid Recovery Strategies for Anaerobic Digestion of Sole Corn Stover: Methane Production Efficiency and Dominant Microbial Responses
Process Exploration of Domestication, Start-Up and Rapid Recovery Strategies for Anaerobic Digestion of Sole Corn Stover: Methane Production Efficiency and Dominant Microbial Responses Open
View article: Reutilization of Digestate (Residue and Liquid) in the Anaerobic Digestion of Sole Corn Stover: Digestate-Derived Biochar Preparation, Methane Performance and Dominant Microbial Community Responses
Reutilization of Digestate (Residue and Liquid) in the Anaerobic Digestion of Sole Corn Stover: Digestate-Derived Biochar Preparation, Methane Performance and Dominant Microbial Community Responses Open
View article: Effects of four soil types on growth responses and nutrient stoichiometry in <i>Phellodendron chinense</i> seedlings
Effects of four soil types on growth responses and nutrient stoichiometry in <i>Phellodendron chinense</i> seedlings Open
Phellodendron chinense is an extraordinary medicinal plant, and its stem bark is a famous traditional Chinese medicine in China, containing a number of phytochemicals with biological and pharmacological functions. Studies have shown that t…
View article: Transcriptomic and Translatomic Analyses Reveal Insights into the Signaling Pathways of the Innate Immune Response in the Spleens of SPF Chickens Infected with Avian Reovirus
Transcriptomic and Translatomic Analyses Reveal Insights into the Signaling Pathways of the Innate Immune Response in the Spleens of SPF Chickens Infected with Avian Reovirus Open
Avian reovirus (ARV) infection is prevalent in farmed poultry and causes viral arthritis and severe immunosuppression. The spleen plays a very important part in protecting hosts against infectious pathogens. In this research, transcriptome…
View article: Molecular detection reveals diverse tick-borne bacterial and protozoan pathogens in two tick species from Yingshan County of Hubei Province, China in 2021–2022
Molecular detection reveals diverse tick-borne bacterial and protozoan pathogens in two tick species from Yingshan County of Hubei Province, China in 2021–2022 Open
In this study, a total of 179 ticks infesting ruminant livestock, including 166 Haemaphysalis longicornis ticks and 13 Rhipicephalus microplus ticks were collected from Yingshan county of Hubei province, China in 2021–2022. PCR testing and…
View article: Chicken IFI6 inhibits avian reovirus replication and affects related innate immune signaling pathways
Chicken IFI6 inhibits avian reovirus replication and affects related innate immune signaling pathways Open
Interferon-alpha inducible protein 6 (IFI6) is an important interferon-stimulated gene. To date, research on IFI6 has mainly focused on human malignant tumors, virus-related diseases and autoimmune diseases. Previous studies have shown tha…
View article: A nonuniform demagnetizing field model for both static and dynamic responses of anisotropic magnetoresistive thin film sensors
A nonuniform demagnetizing field model for both static and dynamic responses of anisotropic magnetoresistive thin film sensors Open
In this paper, an anisotropic magnetoresistive (AMR) thin film sensor which can be used for magnetic scale has been prepared, and its output voltage is about 4.7–4.9 mV V −1 . On the basis of the Stoner–Wohlfarth model and with considering…