Hongzhen Luo
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View article: Multifunctional Prussian-Blue-Based Nanocomposite Hydrogel for Infected Wound Regeneration
Multifunctional Prussian-Blue-Based Nanocomposite Hydrogel for Infected Wound Regeneration Open
The wound healing (WH) process is often severely hindered by bacterial infections and prolonged inflammatory responses. To address this problem, we developed a novel injectable nanocomposite DPB-ODQ hydrogel, which comprises polydopamine-m…
View article: Efficient butanol bioproduction from renewable lignocellulosic biomass by an integrated strategy of ternary deep eutectic solvent pretreatment and clostridial fermentation: toward complete utilization of reed straw
Efficient butanol bioproduction from renewable lignocellulosic biomass by an integrated strategy of ternary deep eutectic solvent pretreatment and clostridial fermentation: toward complete utilization of reed straw Open
The main route for biobutanol production is anaerobic clostridial fermentation using corn and sugarcane as substrates. The high-price of raw materials in above processes largely limits its application as an advanced biofuel. The renewable …
View article: The Study of Regioselective Acylation of Geniposide by Using Whole-Cell Biocatalysts in Organic Solvents
The Study of Regioselective Acylation of Geniposide by Using Whole-Cell Biocatalysts in Organic Solvents Open
Geniposide, the predominant bioactive constituent identified in the traditional Chinese medicine herb Gardenia jasminoides, demonstrates clinically significant pharmacological properties. However, the clinical application of geniposide is …
View article: Effect of Different Crushing Methods on Chalcopyrite Liberation and Heavy Media Preconcentration
Effect of Different Crushing Methods on Chalcopyrite Liberation and Heavy Media Preconcentration Open
In order to find a short, economically feasible process for chalcopyrite preconcentration and to provide a reference for the preconcentration of similar copper sulfide ores, the particle size characteristics of the crushed products from a …
View article: Optimization of the Process of Chinese Hamster Ovary (CHO) Cell Fed-Batch Culture to Stabilize Monoclonal Antibody Production and Overall Quality: Effect of pH Control Strategies
Optimization of the Process of Chinese Hamster Ovary (CHO) Cell Fed-Batch Culture to Stabilize Monoclonal Antibody Production and Overall Quality: Effect of pH Control Strategies Open
Monoclonal antibodies (mAbs) used in biomedical research and therapeutic applications are primarily produced by Chinese hamster ovary (CHO) cells via fed-batch culture. The growing need for elevated quantities of biologics mandates the con…
View article: Efficient production of fermentable sugars from common reed biomass through hydrothermal and citric acid pretreatment processes
Efficient production of fermentable sugars from common reed biomass through hydrothermal and citric acid pretreatment processes Open
Producing fermentable sugars from lignocellulosic biomass could provide renewable substrate for biofuel production by microbial fermentation. However, the structure of lignocellulose hinders enzymatic saccharification efficiency to obtain …
View article: Mineralogical characteristic and beneficiation evaluation of rare earth carbonate wall rock
Mineralogical characteristic and beneficiation evaluation of rare earth carbonate wall rock Open
In order to rationalize the development and utilization of the wall rock discarded during rare earth mining, chemical analysis, inductively coupled plasma-atomic emission spectroscopy, X-ray diffraction analysis, artificial panning, optica…
View article: Enhancing and stabilizing monoclonal antibody production by Chinese hamster ovary (CHO) cells with optimized perfusion culture strategies
Enhancing and stabilizing monoclonal antibody production by Chinese hamster ovary (CHO) cells with optimized perfusion culture strategies Open
The perfusion medium is critical in maintaining high cell concentration in cultures for the production of monoclonal antibody by Chinese hamster ovary cells. In this study, the effects of perfusion culture strategies when using different m…
View article: A facile and efficient synthesis approach of salidroside esters by whole-cell biocatalysts in organic solvents
A facile and efficient synthesis approach of salidroside esters by whole-cell biocatalysts in organic solvents Open
Salidroside, the main bioactive compound isolated from the plant source of Rhodiola rosea L, possesses broad-spectrum pharmacological activities, but suffers from the low cell membranes permeability and alimentary absorption due to its hig…
View article: Toxicity and inhibition mechanism of gallic acid on physiology and fermentation performance of Escherichia coli
Toxicity and inhibition mechanism of gallic acid on physiology and fermentation performance of Escherichia coli Open
Gallic acid is a natural phenolic acid that has a stress inhibition effect on Escherichia coli . This study by integrates fermentation characteristics and transcriptional analyses to elucidate the physiological mechanism of E. coli 3110 re…
View article: Toxicity and inhibition mechanism of gallic acid on physiology and fermentation performance of Escherichia coli
Toxicity and inhibition mechanism of gallic acid on physiology and fermentation performance of Escherichia coli Open
Gallic acid is a natural phenolic acid that has a stress inhibition effect on Escherichia coli. This study elucidates the physiological mechanism of E. coli 3110 response to gallic acid by integrating fermentation characteristics and trans…
View article: Prediction of phenolic compounds and glucose content from dilute inorganic acid pretreatment of lignocellulosic biomass using artificial neural network modeling
Prediction of phenolic compounds and glucose content from dilute inorganic acid pretreatment of lignocellulosic biomass using artificial neural network modeling Open
Dilute inorganic acids hydrolysis is one of the most promising pretreatment strategies with high recovery of fermentable sugars and low cost for sustainable production of biofuels and chemicals from lignocellulosic biomass. The diverse phe…
View article: Significantly Enhanced Synthesis of Aromatic Esters of Arbutin Catalyzed by Immobilized Lipase in Co-solvent Systems
Significantly Enhanced Synthesis of Aromatic Esters of Arbutin Catalyzed by Immobilized Lipase in Co-solvent Systems Open
Highly efficient and regioselective synthesis of pharmacologically interesting aromatic esters of arbutin catalyzed by immobilized lipase from Penicillium expansum in co-solvent systems was successfully carried out. As compared to tetrahyd…
View article: Isolation, Identification and Antimicrobial Evaluation of Bactericides Secreting Bacillus subtilis Natto as a Biocontrol Agent
Isolation, Identification and Antimicrobial Evaluation of Bactericides Secreting Bacillus subtilis Natto as a Biocontrol Agent Open
Herein, a bactericide-secreting Bacillus strain, potentially useful as a biocontrol agent, was isolated from the commercial Yanjing Natto food. Following the biochemical and physiological evaluation, the molecular identification was perfor…
View article: Sustainable Biotransformation of Oleic Acid to 10-Hydroxystearic Acid by a Recombinant Oleate Hydratase from Lactococcus garvieae
Sustainable Biotransformation of Oleic Acid to 10-Hydroxystearic Acid by a Recombinant Oleate Hydratase from Lactococcus garvieae Open
Enzymatic hydration of oleic acid into 10-hydroxystearic acid (10-HSA) represents a theme of substantial scientific and practical interest. In this study, a fatty acid hydratase (OHase) from Lactococcus garvieae was cloned and expressed in…
View article: Metabolic Engineering and Fermentation Process Strategies for L-Tryptophan Production by Escherichia coli
Metabolic Engineering and Fermentation Process Strategies for L-Tryptophan Production by Escherichia coli Open
L-tryptophan is an essential aromatic amino acid that has been widely used in medicine, food, and animal feed. Microbial biosynthesis of L-tryptophan through metabolic engineering approaches represents a sustainable, cost-effective, and en…
View article: Co-production of solvents and organic acids in butanol fermentation by<i>Clostridium acetobutylicum</i>in the presence of lignin-derived phenolics
Co-production of solvents and organic acids in butanol fermentation by<i>Clostridium acetobutylicum</i>in the presence of lignin-derived phenolics Open
Lignin-derived phenolics enhance solvent and organic acid biosynthesis in butanol fermentation byClostridium acetobutylicumATCC 824.