Miao Yu
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View article: Pharmacokinetics and pharmacodynamics studies of Relugolix long-acting microcrystalline formulation in male Beagle dogs
Pharmacokinetics and pharmacodynamics studies of Relugolix long-acting microcrystalline formulation in male Beagle dogs Open
Relugolix is the first oral GnRH receptor antagonist. However, its oral formulation requires daily administration, leading to poor patient adherence and suboptimal treatment outcomes for long-term users. To address these issues, we develop…
View article: P-896. Artificial Intelligence Performs Well in Assessing the Clarity of Definitions of Variables in Periprosthetic Joint Infection Studies
P-896. Artificial Intelligence Performs Well in Assessing the Clarity of Definitions of Variables in Periprosthetic Joint Infection Studies Open
Background Artificial intelligence (AI) has the potential to improve healthcare research methodologies, particularly in addressing the need for consistency and clarity in defining variables in observational studies. However, concerns exist…
View article: Identification of cell surface markers for acute myeloid leukemia prognosis based on multi-model analysis
Identification of cell surface markers for acute myeloid leukemia prognosis based on multi-model analysis Open
Given the extremely high inter-patient heterogeneity of acute myeloid leukemia (AML), the identification of biomarkers for prognostic assessment and therapeutic guidance is critical. Cell surface markers (CSMs) have been shown to play an i…
View article: Guillain-Barre syndrome following COVID-19 vaccines: A review of literature
Guillain-Barre syndrome following COVID-19 vaccines: A review of literature Open
Objective This study aimed to retrospectively analyze reported Guillain–Barré syndrome (GBS) cases that occurred after COVID-19 vaccination. Methods Case reports of GBS following COVID-19 vaccination that were published before May 14, 2022…
View article: Electrophysiologic Characteristics of Nitrous-Oxide-Associated Peripheral Neuropathy: A Retrospective Study of 76 Patients
Electrophysiologic Characteristics of Nitrous-Oxide-Associated Peripheral Neuropathy: A Retrospective Study of 76 Patients Open
N2O-associated peripheral neuropathy can lead to sensory and motor nerve injury, with axonal injury being the most common. Injuries were more severe in the lower limbs. Prolonged N2O exposure and disease course increased the severity of mo…
View article: Analysis of clinical characteristics and prognostic factors in 110 patients with nitrous oxide abuse
Analysis of clinical characteristics and prognostic factors in 110 patients with nitrous oxide abuse Open
Purpose To review the clinical symptoms, auxiliary examination findings, and outcomes of patients with nitrous oxide (N 2 O) abuse, and analyze the factors that affect outcomes. Methods Patients with N 2 O abuse treated in the Department o…
View article: Outpatient transition to extended-release injectable naltrexone for patients with opioid use disorder: A phase 3 randomized trial
Outpatient transition to extended-release injectable naltrexone for patients with opioid use disorder: A phase 3 randomized trial Open
A 7-day detoxification protocol with NTX alone or NTX + BUP provided similar rates of induction to XR-NTX as placebo. For those inducted onto XR-NTX, management of opioid withdrawal symptoms prior to induction was achieved in a structured …