Horacio E. Cingolani
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View article: Cardiac hypertrophy reduction in SHR by specific silencing of myocardial Na<sup>+</sup>/H<sup>+</sup>exchanger
Cardiac hypertrophy reduction in SHR by specific silencing of myocardial Na<sup>+</sup>/H<sup>+</sup>exchanger Open
We examined the effect of specific and local silencing of sodium/hydrogen exchanger isoform 1 (NHE1) with a small hairpin RNA delivered by lentivirus (L-shNHE1) in the cardiac left ventricle (LV) wall of spontaneously hypertensive rats, to…
View article: El receptor cardíaco de mineralocorticoides: pasado, presente y futuro
El receptor cardíaco de mineralocorticoides: pasado, presente y futuro Open
Tres ensayos clínicos realizados en el transcurso de los últimos 20 años –RALES, EPHESUS y EMPHASIS-HF- marcaron un nuevo hito en el tratamiento de la insuficiencia cardíaca (IC)1-3. Demostraron que el uso de antagonistas del receptor de m…