H. D. Revanasiddappa
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View article: New pyrazole-based Schiff base ligand and its Ni(ii) and Co(iii) complexes as antibacterial and anticancer agents: Synthesis, characterization, and molecular docking studies
New pyrazole-based Schiff base ligand and its Ni(ii) and Co(iii) complexes as antibacterial and anticancer agents: Synthesis, characterization, and molecular docking studies Open
New Schiff base of 5-amino-1,3-diphenyl-1 H -pyrazole with 5-bromo salicylaldehyde and its cobalt and nickel complexes have been synthesized by condensation reaction. The synthesized compounds were characterized by numerous spectral (UV–vi…
View article: Silver vanadate nanoparticles: Green synthesis, enhanced photocatalytic and antibacterial activity
Silver vanadate nanoparticles: Green synthesis, enhanced photocatalytic and antibacterial activity Open
Nanotechnology provides a very good chance to research and develop multipurpose nanomaterials because of their smaller size, larger surface area, low cost, and nanoscale materials, which are auspicious tools for many biological application…
View article: Tetradentate Schiff Base Derived from Lamotrigine as Chemosensor for the Selective Detection of Cu(II) Ions and Investigation of Binding Affinities with BSA, DNA, P53 Cancer Mutant Protein, Cu, Zn-SOD and Insulin Receptor Protein Using Molecular Docking Studies
Tetradentate Schiff Base Derived from Lamotrigine as Chemosensor for the Selective Detection of Cu(II) Ions and Investigation of Binding Affinities with BSA, DNA, P53 Cancer Mutant Protein, Cu, Zn-SOD and Insulin Receptor Protein Using Molecular Docking Studies Open
View article: Novel Benzimidazole Derived Imine Ligand and Its Co(III) and Cu(II) Complexes as Anticancer Agents: Chemical Synthesis, DFT Studies, In Vitro and In Vivo Biological Investigations
Novel Benzimidazole Derived Imine Ligand and Its Co(III) and Cu(II) Complexes as Anticancer Agents: Chemical Synthesis, DFT Studies, In Vitro and In Vivo Biological Investigations Open
The emerging interest in the field of coordination chemistry and their biological applications has created a novel impact in the field of chemical biology. With this motivation, in this work we have synthesized a novel benzimidazole derive…
View article: Synthesis and Spectral Characterisation of new Benzothiazole-based Schiff Base Ligand and its Co(III) and Ni(II) Complexes as DNA Binding and DNA Cleavage Agents
Synthesis and Spectral Characterisation of new Benzothiazole-based Schiff Base Ligand and its Co(III) and Ni(II) Complexes as DNA Binding and DNA Cleavage Agents Open
Herein we report the synthesis of Schiff base, 2-((E)-(2-(benzo[d]thiazol-2-yl)phenylimino)methyl)-5-fluorophenol (BTF) and its complexes A1 [Co(BTF)2Cl], A2 [Co(BTF)PhCl]Cl, A3 [Ni(BTF)2] and A4 [Ni(BTF)Ph]Cl. The synthesized compounds we…
View article: CCDC 1956098: Experimental Crystal Structure Determination
CCDC 1956098: Experimental Crystal Structure Determination Open
An entry from the Cambridge Structural Database, the world’s repository for small molecule crystal structures. The entry contains experimental data from a crystal diffraction study. The deposited dataset for this entry is freely available …
View article: CCDC 1956099: Experimental Crystal Structure Determination
CCDC 1956099: Experimental Crystal Structure Determination Open
An entry from the Cambridge Structural Database, the world’s repository for small molecule crystal structures. The entry contains experimental data from a crystal diffraction study. The deposited dataset for this entry is freely available …
View article: Molecular Docking and Extended Spectroscopy to Binding Characterizations: Etoposide a Glycoside of Podophyllotoxin with Bovine Serum Albumin
Molecular Docking and Extended Spectroscopy to Binding Characterizations: Etoposide a Glycoside of Podophyllotoxin with Bovine Serum Albumin Open
A significant soluble protein, specifically bovine serum albumin (BSA) plays an efficient role in drug delivery, and etoposide (ETS) is used to cure various cancers. Binding interaction between ETS and BSA examined by 3D, emission, synchro…
View article: Biological Potency of New Benzimidazole Derived Imine Based Ligand and its Co(III), Ni(II), Cu(II) and Pt(II) Complexes: Synthesis, Structure, Antimicrobial, Antioxidant and BSA Interaction Studies
Biological Potency of New Benzimidazole Derived Imine Based Ligand and its Co(III), Ni(II), Cu(II) and Pt(II) Complexes: Synthesis, Structure, Antimicrobial, Antioxidant and BSA Interaction Studies Open
In this study, we report the synthesis and characterization of transition metal complexes (MC1, MC2, MC3, MC4) where M= Co(III), Ni(II), Cu(II) and Pt(II), respectively, using a new imine-based ligand, 2-{(E)-[(1H-benzimidazol-2-ylmethyl)i…
View article: Development and validation of spectrophotometric methods for the sensitive and selective determination of lamotrigine in pharmaceuticals using bromocresol purple
Development and validation of spectrophotometric methods for the sensitive and selective determination of lamotrigine in pharmaceuticals using bromocresol purple Open
Three simple, selective and sensitive methods have been developed and validated for the determination of lamotrigine (LMT) in pure drug and in tablets. The first method (method A) is based on the formation of ion-pair complex between LMT a…
View article: Molecular mechanistic vision on binding interaction of triptan drug, a serotonin (5-HT1) agonist with human serum albumin through multispectral and computational assessments
Molecular mechanistic vision on binding interaction of triptan drug, a serotonin (5-HT1) agonist with human serum albumin through multispectral and computational assessments Open
The triptan drug such as eletriptan in combination with hydrochloride (ETP) is a 5-HT1 receptor agonist used to treat the migraine headache. Human serum albumin (HSA), the fundamental serum protein, executes various functions, that include…
View article: DNA binding, BSA interaction and<i>in-vitro</i>antimicrobial studies of Cu(II), Co(III), Ni(II) and VO(IV) complexes with a new Schiff base
DNA binding, BSA interaction and<i>in-vitro</i>antimicrobial studies of Cu(II), Co(III), Ni(II) and VO(IV) complexes with a new Schiff base Open
A new bidentate (E)-2-((3-(benzyloxypyridinylimino) methyl)-6-methoxyphenol (L) and its complexes such as [Cu(L)2] (C1), [Cu(L)(Phen)] (C2), [Co(L)2] (C3), [Co(L)(Phen)] (C4), [Ni(L)2] (C5), [Ni(L)(Phen)] (C6), [VO(L)2] (C7) and [VO(L)(Phe…
View article: Molecular docking and multitudinous spectroscopic studies to elucidating proton-pump inhibitor a lansoprazole binding interaction with bovine serum albumin
Molecular docking and multitudinous spectroscopic studies to elucidating proton-pump inhibitor a lansoprazole binding interaction with bovine serum albumin Open
A carrier protein called bovine serum albumin (BSA) interaction with proton-pump inhibitor such as lansoprazole (LSE) has been investigated at 295, 303 and 311 K in pH 7.40 by docking and [UV–vis, CD, FT–IR and fluorescence (emission, 3D a…
View article: Spectroscopic and molecular docking elucidation to binding characteristics of bovine serum albumin with bupropion an aminoketone-medication for nicotine addiction
Spectroscopic and molecular docking elucidation to binding characteristics of bovine serum albumin with bupropion an aminoketone-medication for nicotine addiction Open
One of the highly soluble protein presents in circulatory system of bovine body is bovine serum albumin (BSA). Bupropion hydrochloride (BRN) served to treat prime smoking cessation and disorder due to depressive. BRN binding to BSA was stu…
View article: Sensitive and Selective Extractive Spectrophotometric Method for the Determination of Hydroxyzine Dihydrochloride in Pharmaceuticals
Sensitive and Selective Extractive Spectrophotometric Method for the Determination of Hydroxyzine Dihydrochloride in Pharmaceuticals Open
Hydroxyzine dihydrochloride (HDH), a piperazine H1-receptor antagonist and antihistamine, is a rapid acting anxiolytic used principally as an anti-emetic. A sensitive, selective, and precise and accurate spectrophotometric method based on …
View article: Co(III) and VO(IV) complexes with a new bidentate Schiff base: Interaction with BSA and antimicrobial studies
Co(III) and VO(IV) complexes with a new bidentate Schiff base: Interaction with BSA and antimicrobial studies Open
A Schiff base ligand L was prepared from the condensation of 2-amino-3-benzyloxypyridine and 5-chlorosalicylaldehyde. The ligand forms complexes with Co(III) and VO(IV) in good yield. Design, synthesized and characterization of cobalt(III)…
View article: CCDC 1548542: Experimental Crystal Structure Determination
CCDC 1548542: Experimental Crystal Structure Determination Open
An entry from the Cambridge Structural Database, the world’s repository for small molecule crystal structures. The entry contains experimental data from a crystal diffraction study. The deposited dataset for this entry is freely available …
View article: CCDC 1911324: Experimental Crystal Structure Determination
CCDC 1911324: Experimental Crystal Structure Determination Open
An entry from the Cambridge Structural Database, the world’s repository for small molecule crystal structures. The entry contains experimental data from a crystal diffraction study. The deposited dataset for this entry is freely available …
View article: Preparation, spectral characterization and biological applications of Schiff base ligand and its transition metal complexes
Preparation, spectral characterization and biological applications of Schiff base ligand and its transition metal complexes Open
The present work deals with the study of chemical synthesis of Schiff base ligand, (L) derived from 5-amino-4H-1,2,4-triazole-3-thiol and 3-hydroxy-4-methoxy benzaldehyde and its Cu(II), Co(II), Mn(II), Zn(II) and Ni(II) complexes in 2:1 s…
View article: CCDC 1911325: Experimental Crystal Structure Determination
CCDC 1911325: Experimental Crystal Structure Determination Open
An entry from the Cambridge Structural Database, the world’s repository for small molecule crystal structures. The entry contains experimental data from a crystal diffraction study. The deposited dataset for this entry is freely available …
View article: Synthesis, spectroscopic characterization, crystal structure and Hirshfeld surface analysis of Co(III), Ni(II) and VO(IV) metal complexes with a novel Schiff base ligand and their antimicrobial activities
Synthesis, spectroscopic characterization, crystal structure and Hirshfeld surface analysis of Co(III), Ni(II) and VO(IV) metal complexes with a novel Schiff base ligand and their antimicrobial activities Open
A new series of transition metal complexes of Co(III), Ni(II) and VO(IV) was synthesized with the bidentate Schiff base ligand (HL) derived from the condensation of 2-amino-3-benzyloxypyridine and 5-bromo salicylaldehyde. The synthesized S…
View article: Synthesis, Spectral Characterization, in vitro Antimicrobial and Anthelmintic Evaluations of Cu(II) Complexes with a New Schiff Base
Synthesis, Spectral Characterization, in vitro Antimicrobial and Anthelmintic Evaluations of Cu(II) Complexes with a New Schiff Base Open
Novel Schiff base ligand (E)-2-((3-(benzyloxypyridinylimino) methyl)-4-bromophenol (HL) was synthesized. Using this Schiff base ligand, two new copper(II) complexes, C1 and C2 were prepared. Analytical techniques such as I…
View article: A Diversified Spectrometric and Molecular Docking Technique to Biophysical Study of Interaction between Bovine Serum Albumin and Sodium Salt of Risedronic Acid, a Bisphosphonate for Skeletal Disorders
A Diversified Spectrometric and Molecular Docking Technique to Biophysical Study of Interaction between Bovine Serum Albumin and Sodium Salt of Risedronic Acid, a Bisphosphonate for Skeletal Disorders Open
The binding interaction between bovine serum albumin (BSA) and sodium salt of risedronic acid (RSN) was studied by using the FT-IR (Fourier transform infrared), UV-Vis (ultraviolet–visible), fluorescence (emission and synchronous), CD (cir…
View article: Synthesis and Characterization of Oxidovanadium(IV) Complexes of 2-((E)-(6-Fluorobenzo[d]thiazol-2-ylimino)methyl)-6-methoxyphenol and Their Antimicrobial, Antioxidant, and DNA-Binding Studies
Synthesis and Characterization of Oxidovanadium(IV) Complexes of 2-((E)-(6-Fluorobenzo[d]thiazol-2-ylimino)methyl)-6-methoxyphenol and Their Antimicrobial, Antioxidant, and DNA-Binding Studies Open
Two novel oxidovanadium(IV) complexes with a new bidentate (O- and N-) imine-based ligand 2-((E)-(6-fluorobenzo[d]thiazol-2-ylimino)methyl)-6-methoxyphenol (HL) were synthesized under in situ experimental condition where VOSO 4 acts as a k…
View article: Synthesis and Characterization of Cobalt(III) and Copper(II) Complexes of 2-((E)-(6-Fluorobenzo[d]thiazol-2-ylimino) methyl)-4-chlorophenol: DNA Binding and Nuclease Studies—SOD and Antimicrobial Activities
Synthesis and Characterization of Cobalt(III) and Copper(II) Complexes of 2-((E)-(6-Fluorobenzo[d]thiazol-2-ylimino) methyl)-4-chlorophenol: DNA Binding and Nuclease Studies—SOD and Antimicrobial Activities Open
A bidentate (N- and O-) imine-based ligand (L 1 ) and its metal complexes of types [(L 1 ) 2 ] (C 1 ) , [(L 1 )(Phen)] (C 2 ) , [(L 1 ) 2 ] (C 3 ) , and [(L 1 )(Phen)] (C 4 ) (L 1 = 2-((E)-(6-fluorobenzo[d]thiazol-2-ylimino)methyl)-4-chlor…
View article: CCDC 1821708: Experimental Crystal Structure Determination
CCDC 1821708: Experimental Crystal Structure Determination Open
An entry from the Cambridge Structural Database, the world’s repository for small molecule crystal structures. The entry contains experimental data from a crystal diffraction study. The deposited dataset for this entry is freely available …
View article: Co(III) and Cu(II) benzimidazole Schiff base complexes: Synthesis, Characterization and DNA binding and cleavage activity
Co(III) and Cu(II) benzimidazole Schiff base complexes: Synthesis, Characterization and DNA binding and cleavage activity Open
Four new cobalt(III) and copper(II) complexes with 2- (5,6-Dihydrobenzo[4,5]imidazo[1,2-c]quinazolin-6-yl)-6-methoxy-phenol were synthesized and characterized by elemental and various spectral analysis.All the synthesized compounds were sc…
View article: CCDC 1537326: Experimental Crystal Structure Determination
CCDC 1537326: Experimental Crystal Structure Determination Open
An entry from the Cambridge Structural Database, the world’s repository for small molecule crystal structures. The entry contains experimental data from a crystal diffraction study. The deposited dataset for this entry is freely available …
View article: CCDC 1485219: Experimental Crystal Structure Determination
CCDC 1485219: Experimental Crystal Structure Determination Open
An entry from the Cambridge Structural Database, the world’s repository for small molecule crystal structures. The entry contains experimental data from a crystal diffraction study. The deposited dataset for this entry is freely available …
View article: Effect of operational parameters and kinetic study on the photocatalytic degradation of m-cresol purple using irradiated ZnO in aqueous medium
Effect of operational parameters and kinetic study on the photocatalytic degradation of m-cresol purple using irradiated ZnO in aqueous medium Open
A detailed investigation of photocatalytic degradation of m-cresol purple (mCP) dye has been carried out in aqueous heterogeneous medium containing zinc oxide (ZnO) as the photocatalyst in a batch reactor. The effects of some parameters su…