Rui Li
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View article: Additive effects of Lp(a) and inflammation on cardiovascular risk beyond LDL-C lowering: circulating and genetic evidence from 401,548 adults
Additive effects of Lp(a) and inflammation on cardiovascular risk beyond LDL-C lowering: circulating and genetic evidence from 401,548 adults Open
View article: Stratified Nitrogen Application Enhances Subsoil Carbon Sequestration via Enzyme-Mediated Pathways in Straw-Incorporated Croplands of North China Plain
Stratified Nitrogen Application Enhances Subsoil Carbon Sequestration via Enzyme-Mediated Pathways in Straw-Incorporated Croplands of North China Plain Open
Nitrogen (N) fertilization critically regulates the storage and availability of soil carbon (C) and N pools. However, the internal mechanism through which stratified N application affects soil organic carbon (SOC) sequestration and soil qu…
View article: Functional role of <i>FvMdm10</i> in stress response, pathogenicity, and fumonisins production in <i>fusarium verticillioides</i>
Functional role of <i>FvMdm10</i> in stress response, pathogenicity, and fumonisins production in <i>fusarium verticillioides</i> Open
Endoplasmic reticulum-mitochondrial encounter structure (ERMES), the protein complex that tethers mitochondria and endoplasmic reticulum, is critical for mitochondrial functions and various cellular processes. Our preliminary studies showe…
View article: A CesiumJS-based algorithm for 2D and 3D visualization of phased array antenna beams in satellite communications
A CesiumJS-based algorithm for 2D and 3D visualization of phased array antenna beams in satellite communications Open
The rapid advancement of aerospace technology has driven the widespread adoption of phased array antennas in satellite communication systems. To address the need for analyzing the operational characteristics of phased array beams across di…
View article: Residential burning is a significant source of soluble iron to the ocean
Residential burning is a significant source of soluble iron to the ocean Open
Understanding the physicochemical processes that supply atmospheric aerosol iron (Fe) to the ocean is crucial in our understanding of global biogeochemical cycles. Anthropogenic emissions contribute significant fluxes of aerosol Fe to the …
View article: How Sponge City Policy Influences Urban Design in China—A Study from the Perspective of Parametric Design
How Sponge City Policy Influences Urban Design in China—A Study from the Perspective of Parametric Design Open
Sponge city theory utilizes policy-driven design to mitigate urban flooding and shape urban development. However, existing approaches primarily focus on micro-scale landscape facilities and performance assessments, overlooking the integrat…
View article: ALDH2 Suppresses Glycolysis in Hepatocellular Carcinoma via TRIM21-Mediated GLUT1 Degradation
ALDH2 Suppresses Glycolysis in Hepatocellular Carcinoma via TRIM21-Mediated GLUT1 Degradation Open
Aldehyde dehydrogenase 2 (ALDH2) detoxifies alcohol-derived acetaldehyde and lipid aldehydes from lipid peroxidation. A single nucleotide polymorphism of ALDH2 rs671, representing 30-50% East Asians and featuring ALDH2 deficiency, is assoc…
View article: Cistanche tubulosa glycosides ameliorate cognitive decline in APP/PS1 mice via modulation of gut microbiota and fatty acid metabolism: insights from multi-omics and experimental validation
Cistanche tubulosa glycosides ameliorate cognitive decline in APP/PS1 mice via modulation of gut microbiota and fatty acid metabolism: insights from multi-omics and experimental validation Open
Objective The dried succulent stem of C. tubulosa (Schenk) Wight has long been used as herbal medicine in China and other regions of Asia for its tonifying properties. This study aimed to elucidate the pharmacological mechanisms of the tot…
View article: Different surface modified polystyrene nanoplastics can affect growth adaptability of Skeletonema costatum to heat stress
Different surface modified polystyrene nanoplastics can affect growth adaptability of Skeletonema costatum to heat stress Open
View article: Clinical effects of transumbilical laparoendoscopic single-site extracorporeal surgery in treatment of giant ovarian cysts and huge cystic pelvic masses
Clinical effects of transumbilical laparoendoscopic single-site extracorporeal surgery in treatment of giant ovarian cysts and huge cystic pelvic masses Open
Objective: To explore the clinical efficacy of transumbilical laparoendoscopic single-site extracorporeal surgery (TU-LESS-E) in the treatment of giant ovarian cysts and huge cystic pelvic masses. Methodology: This was a retrospective stud…
View article: Prognostic implications of left ventricular mechanical dispersion in comparison with QRS duration in heart failure with reduced ejection fraction
Prognostic implications of left ventricular mechanical dispersion in comparison with QRS duration in heart failure with reduced ejection fraction Open
In HFrEF patients with medical treatment, LV-MD provides additional information on left ventricular dyssynchrony and has superior prognostic value for left ventricular reverse remodeling compared with QRS duration alone.
View article: Analysis of risk factors and intervention measures for postoperative bleeding in patients with diabetes after proctologic surgery based on a logistic regression model
Analysis of risk factors and intervention measures for postoperative bleeding in patients with diabetes after proctologic surgery based on a logistic regression model Open
Objective The purpose of this study was to analyse the risk factors for bleeding after proctologic surgery, provide a reference for clinical management and improve postoperative recovery in patients. Methods This study retrospectively anal…
View article: Proactive emergency laparoscopic cholecystectomy for complex acute cholecystitis: a prospective cohort at a national emergency center in China
Proactive emergency laparoscopic cholecystectomy for complex acute cholecystitis: a prospective cohort at a national emergency center in China Open
Background: While emergency laparoscopic cholecystectomy (ELC) is the standard treatment for acute cholecystitis (AC), optimal management of complex cases, particularly those with symptom duration ≥7 days or severe inflammation, remains co…
View article: PEDV Nsp14 induces mitophagy-mediated degradation of MAVS to antagonize host innate immunity and facilitate viral proliferation
PEDV Nsp14 induces mitophagy-mediated degradation of MAVS to antagonize host innate immunity and facilitate viral proliferation Open
Porcine epidemic diarrhea virus (PEDV) leads to a high mortality in neonatal piglets and causes serious harm to the global swine industry. PEDV has been shown to exploit diverse strategies for antagonism of host innate immunity and promoti…
View article: Haemodynamic implications of cardiovascular magnetic resonance pulmonary capillary wedge pressure in acute myocardial infarction
Haemodynamic implications of cardiovascular magnetic resonance pulmonary capillary wedge pressure in acute myocardial infarction Open
Aims Cardiovascular magnetic resonance (CMR)-derived pulmonary capillary wedge pressure (PCWP) has demonstrated diagnostic and prognostic utility in heart failure patients. However, its clinical value in acute myocardial infarction (AMI) r…
View article: Efficacy and safety of immunotherapy-based neoadjuvant regimens in locally advanced gastric cancer: a meta-analysis based on high-quality clinical trials
Efficacy and safety of immunotherapy-based neoadjuvant regimens in locally advanced gastric cancer: a meta-analysis based on high-quality clinical trials Open
Background: The integration of chemotherapy, targeted therapy, and immunotherapy has emerged as the latest research focus for locally advanced gastric cancer (LAGC). This study aims to evaluate the efficacy and safety of various immunother…
View article: Author Correction: CD147 regulates the Rap1 signaling pathway to promote proliferation, migration, and invasion, and inhibit apoptosis in colorectal cancer cells
Author Correction: CD147 regulates the Rap1 signaling pathway to promote proliferation, migration, and invasion, and inhibit apoptosis in colorectal cancer cells Open
View article: Early Detection of Pine Wilt Disease by Combining Pigment and Moisture Content Indices Using UAV-Based Hyperspectral Imagery
Early Detection of Pine Wilt Disease by Combining Pigment and Moisture Content Indices Using UAV-Based Hyperspectral Imagery Open
Pine wilt disease (PWD) is characterized by rapid transmission, high mortality rates, and difficulty in control, resulting in severe and destructive impacts on both the ecological environment and socioeconomic development in China. Due to …
View article: Association Between Pulse Pressure and the Risk of Death Events - Beijing Municipality, China, 2010-2021.
Association Between Pulse Pressure and the Risk of Death Events - Beijing Municipality, China, 2010-2021. Open
Our findings emphasize the need to develop comprehensive PP early screening and effective management strategies to reduce mortality, especially among identified high-risk groups.
View article: Coordination of SLC39A1 and DRP1 facilitates HCC recurrence by impairing mitochondrial quality control
Coordination of SLC39A1 and DRP1 facilitates HCC recurrence by impairing mitochondrial quality control Open
Background Despite rapid advances in HCC therapy, surgical resection is still the most effective treatment. However, postoperative relapse develops in a large population and the mechanism remains to be explored. Methods HCC resection sampl…
View article: CD147 regulates the Rap1 signaling pathway to promote proliferation, migration, and invasion, and inhibit apoptosis in colorectal cancer cells
CD147 regulates the Rap1 signaling pathway to promote proliferation, migration, and invasion, and inhibit apoptosis in colorectal cancer cells Open
View article: Combined uranium-series and trace elements analysis in cold seep bivalves: possibility in hundred-year-scale reconstruction of deep-sea temperature and acidification
Combined uranium-series and trace elements analysis in cold seep bivalves: possibility in hundred-year-scale reconstruction of deep-sea temperature and acidification Open
Despite the pivotal role of deep-sea in the global climate system, effective technology is still limited for reconstructing the key parameters of deep-sea environment such as temperature and acidification, especially at the hundred-year sc…
View article: Molecular and biological characteristics of two rare bloodstream Candida isolates: Candida nonsorbophila and Candida sonorensis
Molecular and biological characteristics of two rare bloodstream Candida isolates: Candida nonsorbophila and Candida sonorensis Open
View article: ScMicrobesAtlas: A comprehensive microbial atlas at single-cell resolution in human disease contexts
ScMicrobesAtlas: A comprehensive microbial atlas at single-cell resolution in human disease contexts Open
View article: Prediction of clinical deterioration within one year in chronic obstructive pulmonary disease using the systemic coagulation-inflammation index: a retrospective study employing multiple machine learning method
Prediction of clinical deterioration within one year in chronic obstructive pulmonary disease using the systemic coagulation-inflammation index: a retrospective study employing multiple machine learning method Open
Background Inflammatory response and the coagulation system are pivotal in the pathogenesis of clinical deterioration in chronic obstructive pulmonary disease (COPD), prompting us to hypothesize that the systemic coagulation-inflammation (…
View article: Research Progress on the Current Status of E-Health Literacy and Influencing Factors of Chronic Obstructive Pulmonary Disease Patients
Research Progress on the Current Status of E-Health Literacy and Influencing Factors of Chronic Obstructive Pulmonary Disease Patients Open
View article: Gut microbiome of black soldier fly larvae for efficient use and purification of organic waste: An environmentally friendly development concept
Gut microbiome of black soldier fly larvae for efficient use and purification of organic waste: An environmentally friendly development concept Open
The growing global population and increasing human demands have led to a rise in organic waste volumes. These wastes contain potential risk substances like pathogenic bacteria (PB), antibiotics (ABs), heavy metals (HMs), and microplastics …
View article: 3s-Tpp: A Three-Stage Method for Tomato Sucker Pruning with Main Stem Protection
3s-Tpp: A Three-Stage Method for Tomato Sucker Pruning with Main Stem Protection Open
View article: Feasibility of MR oximetry from a routine myocardial T2 mapping protocol in HFpEF and HFrEF cohorts
Feasibility of MR oximetry from a routine myocardial T2 mapping protocol in HFpEF and HFrEF cohorts Open
View article: Atmospheric Transport of Microplastics from Land to Sea is Inefficient: Evidence from Multimedia Observations
Atmospheric Transport of Microplastics from Land to Sea is Inefficient: Evidence from Multimedia Observations Open