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View article: Investigation and optimization the effect of electrical stimulation parameters on the differentiation of human adipose mesenchymal stem cells into neurons-like cells on carbon nanofibers
Investigation and optimization the effect of electrical stimulation parameters on the differentiation of human adipose mesenchymal stem cells into neurons-like cells on carbon nanofibers Open
Background Neurodegenerative diseases are among the most challenging diseases because neuron cells are not able to regenerate spontaneously. Tissue engineering is one of the most promising stem cell-based therapies. Controlling stem cell d…
View article: Silica NPs–Cytotoxicity Cross-Talk: Physicochemical Principles and Cell Biology Responses
Silica NPs–Cytotoxicity Cross-Talk: Physicochemical Principles and Cell Biology Responses Open
Many advances have been made in the preparation, optimization, and applications of silica nanoparticles (NPs) in biomedical nanotechnology. Considering this, the broader human, environmental, and industrial contacts with these NPs are inev…
View article: Bioceramics/Electrospun Polymeric Nanofibrous and Carbon Nanofibrous Scaffolds for Bone Tissue Engineering Applications
Bioceramics/Electrospun Polymeric Nanofibrous and Carbon Nanofibrous Scaffolds for Bone Tissue Engineering Applications Open
Bone tissue engineering integrates biomaterials, cells, and bioactive agents to propose sophisticated treatment options over conventional choices. Scaffolds have central roles in this scenario, and precisely designed and fabricated structu…
View article: Injectable hydrogels in central nervous system: Unique and novel platforms for promoting extracellular matrix remodeling and tissue engineering
Injectable hydrogels in central nervous system: Unique and novel platforms for promoting extracellular matrix remodeling and tissue engineering Open
Repairing central nervous system (CNS) is difficult due to the inability of neurons to recover after damage. A clinically acceptable treatment to promote CNS functional recovery and regeneration is currently unavailable. According to recen…
View article: Carbon nanofibers fabrication, surface modifications, and application as the innovative substrate for electrical stimulation of neural cell differentiation
Carbon nanofibers fabrication, surface modifications, and application as the innovative substrate for electrical stimulation of neural cell differentiation Open
Engineered nanostructures are innovative and precisely designed, synthesized, and tailored with outstanding physicochemical properties that can be applied as the game-changer in neural tissue engineering. The present study aimed to develop…
View article: Improving motor neuron-like cell differentiation of hEnSCs by the combination of epothilone B loaded PCL microspheres in optimized 3D collagen hydrogel
Improving motor neuron-like cell differentiation of hEnSCs by the combination of epothilone B loaded PCL microspheres in optimized 3D collagen hydrogel Open
Spinal cord regeneration is limited due to various obstacles and complex pathophysiological events after injury. Combination therapy is one approach that recently garnered attention for spinal cord injury (SCI) recovery. A composite of thr…
View article: Preparation of cationized albumin nanoparticles loaded indirubin by high pressure hemogenizer
Preparation of cationized albumin nanoparticles loaded indirubin by high pressure hemogenizer Open
Indirubin can be applied as an anti-cancer drug for inhibition of brain tumors. However, its performance is reduced due to hydrophobicity. In this study, we synthesized cationic human serum albumin (CHSA) nanoparticle by a new hybrid appro…
View article: Study on the Chemistry Identification and Assessment of Antioxidant and Antibacterial Activity of the Biologically Active Constituents from the Roots of Arnebia Euchroma for Promising Application in Nanomedicine and Pharmaceutical
Study on the Chemistry Identification and Assessment of Antioxidant and Antibacterial Activity of the Biologically Active Constituents from the Roots of Arnebia Euchroma for Promising Application in Nanomedicine and Pharmaceutical Open
The recent work aims to investigate different extracts of A. euchroma as a medicinal plant and evaluate their phytochemicals screening, chemical compositions, total phenols content, antioxidant and antimicrobial activities. The plant's roo…
View article: Preparation of cationized albumin nanoparticles loaded indirubin by high pressure hemogenizer
Preparation of cationized albumin nanoparticles loaded indirubin by high pressure hemogenizer Open
Indirubin can be applied as an anti-cancer drug for inhibition of brain tumors. However, its performance is reduced due to hydrophobicity. In this study, we synthesized cationic human serum albumin (CHSA) nanoparticle by a new hybrid appro…
View article: Electro-conductive carbon nanofibers containing ferrous sulfate for bone tissue engineering
Electro-conductive carbon nanofibers containing ferrous sulfate for bone tissue engineering Open
The application of electroactive scaffolds can be promising for bone tissue engineering applications. In the current paper, we aimed to fabricate an electro-conductive scaffold based on carbon nanofibers (CNFs) containing ferrous sulfate. …
View article: Are reported methods for synthesizing nanoparticles and microparticles by magnetic stirrer reproducible
Are reported methods for synthesizing nanoparticles and microparticles by magnetic stirrer reproducible Open
One of the most common tools for fabricating different drug-loaded polymeric particles is magnetic stirrer, a widely-used tool in nano-based drug delivery systems. Typically, the revolutions per minute (rpm) or G-Force of the stirrer are r…
View article: Simple and Robust Fabrication and Characterization of Conductive Carbonized Nanofibers Loaded with Gold Nanoparticles for Bone Tissue Engineering Applications
Simple and Robust Fabrication and Characterization of Conductive Carbonized Nanofibers Loaded with Gold Nanoparticles for Bone Tissue Engineering Applications Open
Bone tissue engineering is a new and applicable emerging approach to repair the bone defects. In this regard, designing and robust fabrication of tissue engineering scaffolds that could provide an appropriate environment for cell prolifera…
View article: Preparation of curcumin-loaded PLGA nanoparticles and investigation of its cytotoxicity effects on human glioblastoma U87MG cells
Preparation of curcumin-loaded PLGA nanoparticles and investigation of its cytotoxicity effects on human glioblastoma U87MG cells Open
Curcumin, an herbal derivative, could be used as anticancer agent in drug delivery. Due to hydrophobic properties of curcumin, its bioavailability decreases to cancer cells. The aim of this study was to prepare curcumin loaded poly (lactic…