R. Houston Thompson
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View article: Comparative analysis of Robotic-Assisted, Laparoscopic, and open radical nephrectomy: Utilization, Costs, and clinical outcomes
Comparative analysis of Robotic-Assisted, Laparoscopic, and open radical nephrectomy: Utilization, Costs, and clinical outcomes Open
View article: Treatment Intensification Prior to Radical Prostatectomy for Clinically Localized Prostate Cancer
Treatment Intensification Prior to Radical Prostatectomy for Clinically Localized Prostate Cancer Open
Current guidelines recommend either radical prostatectomy (RP) or radiation with androgen deprivation therapy (ADT) for unfavorable intermediate- or high-risk prostate cancer. There has been emerging interest in the potential benefits of n…
View article: Artificial Intelligence Use in Medical Education: Best Practices and Future Directions
Artificial Intelligence Use in Medical Education: Best Practices and Future Directions Open
View article: Real-World Management of High-Risk Prostate Cancer Post-Radical Prostatectomy: Insights from a Regional Quality Collaborative
Real-World Management of High-Risk Prostate Cancer Post-Radical Prostatectomy: Insights from a Regional Quality Collaborative Open
Prostate cancer (CaP) remains the most diagnosed malignancy in men, and the incidence of high-grade disease at diagnosis is increasing [...]
View article: “To work with Jews, not for Jews”: a Christian relief worker in the aftermath of the Holocaust
“To work with Jews, not for Jews”: a Christian relief worker in the aftermath of the Holocaust Open
View article: Monte Carlo Models for Eye Plaque Brachytherapy Treatment of Iris Melanoma
Monte Carlo Models for Eye Plaque Brachytherapy Treatment of Iris Melanoma Open
Eye plaque brachytherapy is an effective treatment for eye cancer that uses radioactive seeds (that emit low-energy photons) in an applicator. The purpose of this work is to model eye plaques used to treat iris melanoma and evaluate radiat…
View article: Association of Kidney Cysts With Progressive CKD After Radical Nephrectomy
Association of Kidney Cysts With Progressive CKD After Radical Nephrectomy Open
View article: Navigating Now and Next: Recent Advances and Future Horizons in Robotic Radical Prostatectomy
Navigating Now and Next: Recent Advances and Future Horizons in Robotic Radical Prostatectomy Open
Robotic-assisted radical prostatectomy (RARP) has become the leading approach for radical prostatectomy driven by innovations aimed at improving functional and oncological outcomes. The initial advancement in this field was transperitoneal…
View article: ‘The True Physicians Here are the Padres’: British Christian Army Chaplains and the Liberation of Bergen-Belsen
‘The True Physicians Here are the Padres’: British Christian Army Chaplains and the Liberation of Bergen-Belsen Open
When a senior medical officer summarised the work of army chaplains in the liberation of Bergen-Belsen concentration camp, he said: ‘The true physicians here are the padres, and they are doing more good to the patients than anyone else’. C…
View article: Tubular and Glomerular Size by Cortex Depth as Predictor of Progressive CKD after Radical Nephrectomy for Tumor
Tubular and Glomerular Size by Cortex Depth as Predictor of Progressive CKD after Radical Nephrectomy for Tumor Open
Significance Statement Glomerular size differs by cortex depth. Larger nephrons are prognostic of progressive kidney disease, but it is unknown whether this risk differs by cortex depth or by glomeruli versus proximal or distal tubule size…
View article: Age-Based Versus Young-Adult Thresholds for Nephrosclerosis on Kidney Biopsy and Prognostic Implications for CKD
Age-Based Versus Young-Adult Thresholds for Nephrosclerosis on Kidney Biopsy and Prognostic Implications for CKD Open
Significance Statement Nephrosclerosis (glomerulosclerosis, interstitial fibrosis, and tubular atrophy) is the defining pathology of both kidney aging and CKD. Optimal thresholds for nephrosclerosis that identify persons with a progressive…
View article: Issue Information
Issue Information Open
View article: A Novel PD-L1 Antibody Promotes Antitumor Function of Peripheral Cytotoxic Lymphocytes after Radical Nephrectomy in Patients with Renal Cell Carcinoma
A Novel PD-L1 Antibody Promotes Antitumor Function of Peripheral Cytotoxic Lymphocytes after Radical Nephrectomy in Patients with Renal Cell Carcinoma Open
The intrinsic and acquired resistance to PD-1/PD-L1 immune checkpoint blockade is an important challenge for patients and clinicians because no reliable tool has been developed to predict individualized response to immunotherapy. In this s…
View article: Data from Identification of a Soluble Form of B7-H1 That Retains Immunosuppressive Activity and Is Associated with Aggressive Renal Cell Carcinoma
Data from Identification of a Soluble Form of B7-H1 That Retains Immunosuppressive Activity and Is Associated with Aggressive Renal Cell Carcinoma Open
Purpose: Release of inhibitory coregulatory proteins into the circulation may represent one mechanism by which tumors thwart immune responses. Our objective was to determine whether soluble B7-H1 (sB7-H1) levels in patients with cle…
View article: An Improved Method for Estimating Nephron Number and the Association of Resulting Nephron Number Estimates with Chronic Kidney Disease Outcomes
An Improved Method for Estimating Nephron Number and the Association of Resulting Nephron Number Estimates with Chronic Kidney Disease Outcomes Open
Significance Statement Nephron number currently can be estimated only from glomerular density on a kidney biopsy combined with cortical volume from kidney imaging. Because of measurement biases, refinement of this approach and validation a…
View article: Bladder Recurrence Following Upper Tract Surgery for Urothelial Carcinoma: A Contemporary Review of Risk Factors and Management Strategies
Bladder Recurrence Following Upper Tract Surgery for Urothelial Carcinoma: A Contemporary Review of Risk Factors and Management Strategies Open
View article: Molecular and Immunophenotypic Correlates of Metastatic Epithelioid Angiomyolipoma Include Alterations of <i>TP53</i> , <i>RB1</i> , and <i>ATRX</i>
Molecular and Immunophenotypic Correlates of Metastatic Epithelioid Angiomyolipoma Include Alterations of <i>TP53</i> , <i>RB1</i> , and <i>ATRX</i> Open
Context.— Epithelioid angiomyolipomas (eAMLs) are rare tumors of the kidney that occur in patients with tuberous sclerosis complex or in a sporadic setting; a subset of these tumors exhibit metastatic behavior. Objective.— To analyze molec…
View article: Optimizing Product Wheel Time in Lean Manufacturing Systems
Optimizing Product Wheel Time in Lean Manufacturing Systems Open
Lean manufacturing is a production method focused on reducing production times, eliminating waste, and synchronizing production with fluctuating demand. A standard lean manufacturing methodology is the product wheel, a repeating sequence o…
View article: Surgical Treatment Outcomes For Axillary-subclavian Vein Thrombosis Due To Venous Thoracic Outlet Syndrome
Surgical Treatment Outcomes For Axillary-subclavian Vein Thrombosis Due To Venous Thoracic Outlet Syndrome Open
View article: Discovery of a novel monoclonal PD-L1 antibody H1A that promotes T-cell mediated tumor killing activity in renal cell carcinoma
Discovery of a novel monoclonal PD-L1 antibody H1A that promotes T-cell mediated tumor killing activity in renal cell carcinoma Open
In the last decade, the therapeutic landscape of renal cell carcinoma has rapidly evolved with the addition of PD-1/PD-L1 immune checkpoint inhibitors in the armamentarium of oncologists. Despite clinical evidence of improved oncological o…
View article: Developmental Validation of the <i>forensic</i>GEM Universal Kit for the Extraction of Genomic DNA
Developmental Validation of the <i>forensic</i>GEM Universal Kit for the Extraction of Genomic DNA Open
Commercially available solid-phase DNA extraction kits are commonly used in forensic science today. The forensicGEM™ Universal kit is a new generation approach to DNA extraction that uses a thermophilic proteinase and temperature to yield …
View article: Poster 119: Outcomes after Surgery for Thoracic Outlet Syndrome in Professional Baseball Players: A Matched Cohort Analysis
Poster 119: Outcomes after Surgery for Thoracic Outlet Syndrome in Professional Baseball Players: A Matched Cohort Analysis Open
Objectives: Determine the performance and return to play (RTP) outcomes for professional baseball players that undergo surgical treatment for thoracic outlet syndrome. Methods: All professional baseball players who underwent surgical treat…
View article: Renin Production by Juxtaglomerular Cell Tumors and Clear Cell Renal Cell Carcinoma and the Role of Angiotensin Signaling Inhibitors
Renin Production by Juxtaglomerular Cell Tumors and Clear Cell Renal Cell Carcinoma and the Role of Angiotensin Signaling Inhibitors Open
The identification of renin expression in a subset of CC-RCC may provide a biologic rationale for the high prevalence of HTN and improved PFS with ASI use in hypertensive patients with nonmetastatic CC-RCC.
View article: Vehicle-to-Vehicle Charging Coordination over Information Centric Networking
Vehicle-to-Vehicle Charging Coordination over Information Centric Networking Open
Cities around the world are increasingly promoting electric vehicles (EV) to reduce and ultimately eliminate greenhouse gas emissions. For example, the city of San Francisco aims to increase the number of EVs from tens of thousands to over…
View article: Prevalence, Predictors, and Oncologic Outcomes of Pelvic Organ Involvement in Women Undergoing Radical Cystectomy
Prevalence, Predictors, and Oncologic Outcomes of Pelvic Organ Involvement in Women Undergoing Radical Cystectomy Open
Context.— In women, radical cystectomy includes removal of the bladder, uterus, fallopian tubes, ovaries, and anterior vaginal wall, yet contiguous extension of urothelial carcinoma to all pelvic organs is rare and routine removal may be u…
View article: An Information Centric Framework for Weather Sensing Data
An Information Centric Framework for Weather Sensing Data Open
Weather sensing and forecasting has become increasingly accurate in the last decade thanks to high-resolution radars, efficient computational algorithms, and high-performance computing facilities. Through a distributed and federated networ…
View article: A Clinical Decision Aid to Support Personalized Treatment Selection for Patients with Clinical T1 Renal Masses: Results from a Multi-institutional Competing-risks Analysis
A Clinical Decision Aid to Support Personalized Treatment Selection for Patients with Clinical T1 Renal Masses: Results from a Multi-institutional Competing-risks Analysis Open
View article: Assessment of Risk of Hereditary Predisposition in Patients With Melanoma and/or Mesothelioma and Renal Neoplasia
Assessment of Risk of Hereditary Predisposition in Patients With Melanoma and/or Mesothelioma and Renal Neoplasia Open
In this genetic association study, findings support the continued use of these National Comprehensive Cancer Network criteria and suggest more stringent screening may be warranted in this patient population.
View article: Preface
Preface Open
The popularity of thermoplastic composites as lightweight high-performance engineering materials has been steadily growing in the last several decades.The thermoplastic composite has been used more and more as an alternative material to tr…
View article: Iterative Respacing of Polygonal Curves
Iterative Respacing of Polygonal Curves Open
A $\textit{polygonal curve}$ is a collection of $m$ connected line segments specified as the linear interpolation of a list of points $\{p_0, p_1, \ldots, p_m\}$. These curves may be obtained by sampling points from an oriented curve in $\…