Howard A Fink
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View article: Disparities in the Diagnosis and Treatment of Osteoporosis in Persons with Cognitive Impairment and Dementia
Disparities in the Diagnosis and Treatment of Osteoporosis in Persons with Cognitive Impairment and Dementia Open
View article: Feasibility of Group Telerehabilitation for Older Adults: A Quality Improvement Project
Feasibility of Group Telerehabilitation for Older Adults: A Quality Improvement Project Open
A growing body of evidence suggests group rehabilitation may empower patients to achieve functional goals by leveraging social connectivity. From previous work, we adapted an in-person group for older Veterans to a telerehabilitation group…
View article: Circumstances of clinical fracture events with advancing age in older men
Circumstances of clinical fracture events with advancing age in older men Open
To characterize fracture circumstances by age at time of fracture among community-dwelling older men, we analyzed incident clinical fractures in the Osteoporotic Fractures in Men study. Participants were contacted every 4 mo to identify fr…
View article: THE ASSOCIATION OF ALBUMINURIA WITH FRACTURE RISK
THE ASSOCIATION OF ALBUMINURIA WITH FRACTURE RISK Open
Background: Large blood vessel atherosclerotic cardiovascular disease is associated with hip fracture risk. Here we summarize studies on the association of microvascular disease with hip fracture risk. We further assess whether the risk of…
View article: Back pain precedes sleep problems in older men
Back pain precedes sleep problems in older men Open
Background and Objectives While cross-sectional associations between any pain and sleep problems have been established, longitudinal studies examining the temporal relationship between back pain and multidimensional sleep health remain lim…
View article: EFFECTS OF FRAILTY AND FUNCTIONAL IMPAIRMENT ON THE ASSOCIATIONS OF COGNITIVE IMPAIRMENT AND DEMENTIA WITH HEALTHCARE COSTS
EFFECTS OF FRAILTY AND FUNCTIONAL IMPAIRMENT ON THE ASSOCIATIONS OF COGNITIVE IMPAIRMENT AND DEMENTIA WITH HEALTHCARE COSTS Open
Dementia and cognitive impairment (DCI) are associated with higher total healthcare costs (THC). We sought to determine the fraction of incremental THC of DCI accounted for by frailty and/or functional impairment. We utilized a multi-cohor…
View article: INCREMENTAL HEALTH CARE COSTS OF A SIMPLE MEASURE OF PHENOTYPIC FRAILTY IN OLDER ADULTS
INCREMENTAL HEALTH CARE COSTS OF A SIMPLE MEASURE OF PHENOTYPIC FRAILTY IN OLDER ADULTS Open
Frailty defined by the CHS phenotype is associated with higher subsequent total healthcare expenditures in community-dwelling Medicare beneficiaries after accounting for claims-based cost indicators. However, frailty assessment using the 5…
View article: Incremental healthcare costs of the simple <scp>SOF</scp> measure of phenotypic frailty in community‐dwelling older adults
Incremental healthcare costs of the simple <span>SOF</span> measure of phenotypic frailty in community‐dwelling older adults Open
Background Frailty defined by the Cardiovascular Health Study (CHS) phenotype is associated with higher healthcare expenditures in community‐dwelling Medicare beneficiaries after accounting for claims‐based cost indicators. However, frailt…
View article: Life‐space mobility and cognition in community‐dwelling late‐life women: A cross‐sectional analysis
Life‐space mobility and cognition in community‐dwelling late‐life women: A cross‐sectional analysis Open
Background Life‐space mobility captures the daily, enacted mobility of older adults. We determined cross‐sectional associations between life‐space mobility and cognitive impairment (CI) among community‐dwelling women in the 9th and 10th de…
View article: Publisher Correction: A plasma protein-based risk score to predict hip fractures
Publisher Correction: A plasma protein-based risk score to predict hip fractures Open
View article: Long-term Trajectories of Low Back Pain in Older Men: A Prospective Cohort Study With 10-Year Analysis of the Osteoporotic Fractures in Men Study
Long-term Trajectories of Low Back Pain in Older Men: A Prospective Cohort Study With 10-Year Analysis of the Osteoporotic Fractures in Men Study Open
Although low back pain (LBP) may persist or recur over time, few studies have evaluated the individual course of LBP over a long-term period, particularly among older adults. Based on data from the longitudinal Osteoporotic Fractures in Me…
View article: Hip Fracture Risk Assessment Tools for Adults Aged 80 Years and Older
Hip Fracture Risk Assessment Tools for Adults Aged 80 Years and Older Open
Importance While adults aged 80 years and older account for 70% of hip fractures in the US, performance of fracture risk assessment tools in this population is uncertain. Objective To compare performance of the Fracture Risk Assessment Too…
View article: Association of serum levels of phenylalanine and tyrosine with hip fractures and frailty in older adults: The cardiovascular health study
Association of serum levels of phenylalanine and tyrosine with hip fractures and frailty in older adults: The cardiovascular health study Open
View article: Associations of empirically derived dietary patterns and cognitive performance in older men: Results of the Osteoporotic Fractures in Men (MrOS) study
Associations of empirically derived dietary patterns and cognitive performance in older men: Results of the Osteoporotic Fractures in Men (MrOS) study Open
The results do not support a robust protective effect of the Prudent dietary pattern on cognition in the MrOS cohort. Associations between the Western dietary pattern and better cognitive scores should be interpreted with caution. Further …
View article: A plasma protein-based risk score to predict hip fractures
A plasma protein-based risk score to predict hip fractures Open
As there are effective treatments to reduce hip fractures, identification of patients at high risk of hip fracture is important to inform efficient intervention strategies. To obtain a new tool for hip fracture prediction, we developed a p…
View article: Association of back pain with all-cause and cause-specific mortality among older men: a cohort study
Association of back pain with all-cause and cause-specific mortality among older men: a cohort study Open
Objective We evaluated whether more severe back pain phenotypes—persistent, frequent, or disabling back pain—are associated with higher mortality rate among older men. Methods In this secondary analysis of a prospective cohort, the Osteopo…
View article: Balancing fracture risk versus risk of mortality before fracture among women aged 80 years or older
Balancing fracture risk versus risk of mortality before fracture among women aged 80 years or older Open
Background Most fractures occur in women aged ≥80 years but competing mortality unrelated to fracture may limit the benefit of osteoporosis drug therapy for some women in late life. Our primary aim was to develop separate prediction models…
View article: Large-scale circulating proteome association study (CPAS) meta-analysis identifies circulating proteins and pathways predicting incident hip fractures
Large-scale circulating proteome association study (CPAS) meta-analysis identifies circulating proteins and pathways predicting incident hip fractures Open
Hip fractures are associated with significant disability, high cost, and mortality. However, the exact biological mechanisms underlying susceptibility to hip fractures remain incompletely understood. In an exploratory search of the underly…
View article: 2022 American College of Rheumatology Guideline for the Prevention and Treatment of <scp>Glucocorticoid‐Induced</scp> Osteoporosis
2022 American College of Rheumatology Guideline for the Prevention and Treatment of <span>Glucocorticoid‐Induced</span> Osteoporosis Open
Objective The objective is to update recommendations for prevention and treatment of glucocorticoid‐induced osteoporosis (GIOP) for patients with rheumatic or nonrheumatic conditions receiving >3 months treatment with glucocorticoids (GCs)…
View article: The optimal healthy ranges of thyroid function defined by the risk of cardiovascular disease and mortality: systematic review and individual participant data meta-analysis
The optimal healthy ranges of thyroid function defined by the risk of cardiovascular disease and mortality: systematic review and individual participant data meta-analysis Open
View article: Association of Immune Cell Subsets with Incident Hip Fracture: The Cardiovascular Health Study
Association of Immune Cell Subsets with Incident Hip Fracture: The Cardiovascular Health Study Open
View article: Stressful life events and low back pain in older men: A cross‐sectional and prospective analysis using data from the <scp>MrOS</scp> study
Stressful life events and low back pain in older men: A cross‐sectional and prospective analysis using data from the <span>MrOS</span> study Open
Background Stressful life events, such as loss of a partner, loss of a pet or financial problems, are more common with increasing age and may impact the experience of pain. The aim of the current study is to determine the cross‐sectional a…
View article: The Association of Tryptophan and Its Metabolites With Incident Hip Fractures, Mortality, and Prevalent Frailty in Older Adults: The Cardiovascular Health Study
The Association of Tryptophan and Its Metabolites With Incident Hip Fractures, Mortality, and Prevalent Frailty in Older Adults: The Cardiovascular Health Study Open
Amino acids are the building blocks of proteins, and sufficient protein intake is important for skeletal health. We utilized stored serum from the Cardiovascular Health Study in 1992–1993 to examine the relationship between levels of the e…
View article: Table of Contents
Table of Contents Open
View article: Advantages and Disadvantages of Random Forest Models for Prediction of Hip Fracture Risk Versus Mortality Risk in the Oldest Old
Advantages and Disadvantages of Random Forest Models for Prediction of Hip Fracture Risk Versus Mortality Risk in the Oldest Old Open
Targeted fracture prevention strategies among late‐life adults should balance fracture risk versus competing mortality risk. Models have previously been constructed using Fine‐Gray subdistribution methods. We used a machine learning method…
View article: Plasma Levels of Branched Chain Amino Acids, Incident Hip Fractures, and Bone Mineral Density of the Hip and Spine
Plasma Levels of Branched Chain Amino Acids, Incident Hip Fractures, and Bone Mineral Density of the Hip and Spine Open
Objective Branched chain amino acids (BCAA) are building blocks for protein, an essential component of bone. However, the association of plasma levels of BCAA with fractures in populations outside of Hong Kong or with hip fractures in part…
View article: Mortality Following Hip Fracture in Older Adults With and Without Coronary Heart Disease
Mortality Following Hip Fracture in Older Adults With and Without Coronary Heart Disease Open
View article: Age-Related Factors Associated With The Risk of Hip Fracture
Age-Related Factors Associated With The Risk of Hip Fracture Open
View article: The associations of markers of endothelial dysfunction with hip fracture risk
The associations of markers of endothelial dysfunction with hip fracture risk Open
View article: Cognitive and Functional Trajectories in Older Adults With Prediagnostic Parkinson Disease
Cognitive and Functional Trajectories in Older Adults With Prediagnostic Parkinson Disease Open
Background and objectivesThere is increasing interest in characterizing the earliest phases of Parkinson disease (PD). However, few studies have investigated prediagnostic trajectories of cognition and function. Our objective was to descri…