Howard Collier
YOU?
Author Swipe
View article: Concordance of molecular microbiology and conventional culture techniques for infected diabetic foot ulcer management
Concordance of molecular microbiology and conventional culture techniques for infected diabetic foot ulcer management Open
Aim The management of infected diabetic foot ulcers (DFUs) requires balancing the need for timely interventions against the desire for targeted antibiotic therapy, which relies on laboratory results. This study aimed to evaluate concordanc…
View article: <scp>CODIFI2</scp>: Randomised controlled trial to compare clinical and cost‐effectiveness of swabs versus tissue sampling to inform management of infected diabetic foot ulcers
<span>CODIFI2</span>: Randomised controlled trial to compare clinical and cost‐effectiveness of swabs versus tissue sampling to inform management of infected diabetic foot ulcers Open
BAims/Hypothesis CODIFI2 compared wound swabbing and tissue sampling in people with infected diabetic foot ulcers (DFU) to determine the effects on clinical outcomes. Methods Multicentre, Phase III, prospective, non‐blind, 2‐arm parallel g…
View article: Cost‐effectiveness of swab versus tissue sampling for infected diabetic foot ulcers from the <scp>CODIFI2</scp> randomised controlled trial
Cost‐effectiveness of swab versus tissue sampling for infected diabetic foot ulcers from the <span>CODIFI2</span> randomised controlled trial Open
Aims To compare the cost‐effectiveness of wound swabbing versus tissue sampling for infected diabetic foot ulcers. Methods This multi‐centre, Phase III, prospective, unblinded, two‐arm parallel group, randomised controlled trial compared c…
View article: Swabs versus tissue samples for infected diabetic foot ulcers: the CODIFI2 RCT
Swabs versus tissue samples for infected diabetic foot ulcers: the CODIFI2 RCT Open
Background Foot ulcers affecting people with diabetes (diabetic foot ulcers) often become infected, potentially leading to amputation. Suspected diabetic foot ulcer infection is treated with immediate empiric antimicrobials, with wound sam…
View article: Diabetic foot ulcer photography study: a study within a trial to assess the reliability of two-dimensional (2D) photography for the assessment of ulcer healing in patients with diabetes-related foot ulcers—protocol paper
Diabetic foot ulcer photography study: a study within a trial to assess the reliability of two-dimensional (2D) photography for the assessment of ulcer healing in patients with diabetes-related foot ulcers—protocol paper Open
Background The primary endpoint in diabetes-related foot ulcer (DFU) trials is often time to healing, defined as complete re-epithelialisation with absence of drainage, requiring clinical expert assessment as the gold standard. Central bli…
View article: Early detection to improve outcome in people with undiagnosed psoriatic arthritis: the PROMPT research programme including RCT
Early detection to improve outcome in people with undiagnosed psoriatic arthritis: the PROMPT research programme including RCT Open
Background Longitudinal observational studies suggest that patients who present early to secondary care with psoriatic arthritis have a better outcome. Outcome needs to be measured including domains important to patients. Objectives To ide…
View article: Enhanced surveillance for the detection of psoriatic arthritis in a UK primary care psoriasis population: results from the TUDOR trial
Enhanced surveillance for the detection of psoriatic arthritis in a UK primary care psoriasis population: results from the TUDOR trial Open
Objectives Our objective was to determine whether early detection of undiagnosed PsA in a primary care psoriasis population improves outcome in physical function at 24 months post-registration. Methods A multicentre, prospective, parallel …
View article: DS07 (P066) Our journey to a successful NIHR grant application in dermatological surgery: the HEAL2 study protocol
DS07 (P066) Our journey to a successful NIHR grant application in dermatological surgery: the HEAL2 study protocol Open
Building a successful National Institute for Health and Care Research (NIHR) grant application is a daunting task, typically requiring several years of development. Numerous smaller preliminary ‘feasibility’ studies are required, demonstra…
View article: P066 Our journey to a successful NIHR grant application in dermatological surgery: the HEAL2 study protocol
P066 Our journey to a successful NIHR grant application in dermatological surgery: the HEAL2 study protocol Open
Building a successful National Institute for Health and Care Research (NIHR) grant application is a daunting task, typically requiring several years of development. Numerous smaller preliminary ‘feasibility’ studies are required, demonstra…
View article: Theoretically-informed vs standard cover letter to improve participant response to mailed questionnaire: results of an embedded randomised retention trial
Theoretically-informed vs standard cover letter to improve participant response to mailed questionnaire: results of an embedded randomised retention trial Open
Background Participant non-response is a source of bias in all research, especially in randomised controlled trials. Participants followed-up remotely can have high non-response rates. Four trials have been conducted of a cover letter with…
View article: Approaches and experiences implementing remote, electronic consent at the Leeds Clinical Trials Research Unit
Approaches and experiences implementing remote, electronic consent at the Leeds Clinical Trials Research Unit Open
Background Use of electronic methods to support informed consent (‘eConsent’) is increasingly popular in clinical research. This commentary reports the approach taken to implement electronic consent methods and subsequent experiences from …
View article: Posterior cervical foraminotomy versus anterior cervical discectomy for Cervical Brachialgia: the FORVAD RCT
Posterior cervical foraminotomy versus anterior cervical discectomy for Cervical Brachialgia: the FORVAD RCT Open
Background Posterior cervical foraminotomy and anterior cervical discectomy are routinely used operations to treat cervical brachialgia, although definitive evidence supporting superiority of either is lacking. Objective The primary object…
View article: Multiple Interventions for Diabetic Foot Ulcer Treatment Trial (MIDFUT): study protocol for a randomised controlled trial
Multiple Interventions for Diabetic Foot Ulcer Treatment Trial (MIDFUT): study protocol for a randomised controlled trial Open
Introduction Diabetes affects more than 425 million people worldwide with a lifetime risk of diabetic foot ulcer (DFU) of up to 25%. Management includes wound debridement, wound dressings, offloading, treatment of infection and ischaemia, …
View article: Comparing alternating pressure mattresses and high-specification foam mattresses to prevent pressure ulcers in high-risk patients: the PRESSURE 2 RCT
Comparing alternating pressure mattresses and high-specification foam mattresses to prevent pressure ulcers in high-risk patients: the PRESSURE 2 RCT Open
Background Pressure ulcers (PUs) are a burden to patients, carers and health-care providers. Specialist mattresses minimise the intensity and duration of pressure on vulnerable skin sites in at-risk patients. Primary objective Time to deve…
View article: Pressure RElieving Support SUrfaces: a Randomised Evaluation 2 (PRESSURE 2): study protocol for a randomised controlled trial
Pressure RElieving Support SUrfaces: a Randomised Evaluation 2 (PRESSURE 2): study protocol for a randomised controlled trial Open
ISRCTN01151335 . Registered on 14 May 2013. Protocol version: 5.0, dated 25 September 2015 Trial sponsor: Clare Skinner, Faculty Head of Research Support, University of Leeds, Leeds, LS2 9JT; 0113 343 4897; [email protected].