Howard Peach
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View article: Melanoma: assessment and management summary of the 2022 update of the National Institute for Health and Care Excellence guidelines
Melanoma: assessment and management summary of the 2022 update of the National Institute for Health and Care Excellence guidelines Open
Melanoma is the fifth most common cancer in the UK, accounting for 4% of all new cases of cancer, with a predicted 7% increase in incidence between 2014 and 2035. In parallel, since the initial publication of the National Institute for Hea…
View article: European e-Delphi process to define expert consensus on electrochemotherapy treatment indications, procedural aspects, and quality indicators in melanoma
European e-Delphi process to define expert consensus on electrochemotherapy treatment indications, procedural aspects, and quality indicators in melanoma Open
Background Skin metastases are an important co-morbidity in melanoma. Despite broad adoption, electrochemotherapy implementation is hindered by a lack of treatment indications, uncertainty regarding procedural aspects, and the absence of q…
View article: The neutrophil–lymphocyte ratio and locoregional melanoma: a multicentre cohort study
The neutrophil–lymphocyte ratio and locoregional melanoma: a multicentre cohort study Open
Objectives The neutrophil–lymphocyte ratio (NLR) is an inflammatory biomarker which is useful in cancer prognostication. We aimed to investigate the differences in baseline NLR between patients with localised and metastatic cutaneous melan…
View article: Baseline Neutrophil–Lymphocyte and Platelet–Lymphocyte Ratios as Biomarkers of Survival in Cutaneous Melanoma: A Multicenter Cohort Study
Baseline Neutrophil–Lymphocyte and Platelet–Lymphocyte Ratios as Biomarkers of Survival in Cutaneous Melanoma: A Multicenter Cohort Study Open
This study provides important new data on biomarkers in early-stage melanoma, which contrast with biomarker profiles in advanced disease. These biomarkers may represent the host inflammatory response to melanoma and therefore could help se…
View article: Acral lentiginous melanoma – Is inflammation the missing link?
Acral lentiginous melanoma – Is inflammation the missing link? Open
We propose that repetitive chronic microtrauma, in susceptible individuals, is a significant causative factor in the development of acral lentiginous melanoma (ALM). This observational study documents a possible correlation between anatomi…