Howida S. Abou-Seif
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View article: Therapeutic role of Arabic gum against nicotinamide/streptozotocin-induced diabetes and nephropathy in Wistar rats
Therapeutic role of Arabic gum against nicotinamide/streptozotocin-induced diabetes and nephropathy in Wistar rats Open
Background Chronic kidney disease is mainly caused by diabetic nephropathy and also causes a lot of suffering and death for people with diabetes, as one of the worst long-term complications. Arabic gum (AG) has been reported to have antiox…
View article: Anti-carcinogenic effects and mechanisms of actions of Citrus limon fruit peel hydroethanolic extract and limonene in diethylnitrosmine/2-acetylaminofluorene-induced hepatocellular carcinoma in Wistar rats
Anti-carcinogenic effects and mechanisms of actions of Citrus limon fruit peel hydroethanolic extract and limonene in diethylnitrosmine/2-acetylaminofluorene-induced hepatocellular carcinoma in Wistar rats Open
Hepatocellular carcinoma (HCC) is the third most common cause of cancer death and disability in the world. Citrus species and their constituents have many biological activities including antioxidant, anti-inflammatory and anti-carcinogenic…
View article: Lactobacillus kefiri Suppresses Inflammatory Cytokine Expression and Induces Apoptosis in Breast Cancerous Cells in Rat Model
Lactobacillus kefiri Suppresses Inflammatory Cytokine Expression and Induces Apoptosis in Breast Cancerous Cells in Rat Model Open
DMBA reduced TNFR1, cytochrome c, TRADD, and Bax levels, while increasing Bcl-2 level. L. kefiri reversed these effects, promoting apoptosis in cancer cells. It also improved liver and kidney function markers, reduced oxidative stress and …
View article: Antihyperlipidemic and cardiopreventive properties of Arabic gum in nicotinamide/streptozotocin-induced diabetic rats
Antihyperlipidemic and cardiopreventive properties of Arabic gum in nicotinamide/streptozotocin-induced diabetic rats Open
Background/Aim Diabetes mellitus (DM) and its complications have a negative impact on human health and the economy worldwide. Diabetic patients are at a high risk of dying from cardiovascular diseases. Arabic gum (AG) is a natural product …
View article: Cardioprotective effects of metformin and alpha lipoic acid against myocardial complications induced by hypothyroidism in rats
Cardioprotective effects of metformin and alpha lipoic acid against myocardial complications induced by hypothyroidism in rats Open
The therapeutic effects of alpha lipoic acid (LA) and metformin (MET) against the myocardial complications associated with hypothyroidism were assessed in the current study. Rats were divided into three groups: control, hypothyroidism mode…
View article: Origanum majorana L. extract alleviates dexamethasone-induced hepatotoxicity, oxidative stress and pathological alterations in vivo
Origanum majorana L. extract alleviates dexamethasone-induced hepatotoxicity, oxidative stress and pathological alterations in vivo Open
Background Origanum majorana ( O. majorana ) is one of the most widely used herbs in Egypt due to its antioxidant, anti-inflammatory, anti-genotoxic, antimutagenic, anticoagulant and beneficial properties. Our study's main goal is to deter…
View article: Gold nanoparticles combined baker’s yeast as a successful approach for breast cancer treatment
Gold nanoparticles combined baker’s yeast as a successful approach for breast cancer treatment Open
View article: Thymus vulgaris extract modulates dexamethasone induced liver injury and restores the hepatic antioxidant redox system
Thymus vulgaris extract modulates dexamethasone induced liver injury and restores the hepatic antioxidant redox system Open
Background The liver is the largest important organ and the site for essential biochemical reactions and detoxifying toxic substances in the human body. Long-term, high-dose dexamethasone administration can cause severe alterations in live…