Huah Shin Ng
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View article: Associations of Commonly Used Concomitant Medications With Survival and Adverse Event Outcomes in Breast Cancer
Associations of Commonly Used Concomitant Medications With Survival and Adverse Event Outcomes in Breast Cancer Open
Background The impact of commonly used non‐cancer medications on breast cancer outcomes remains underexplored in large datasets. Aims To evaluate the associations between commonly used non‐cancer medications and survival as well as adverse…
View article: Provision of on-call pharmacist services across public hospitals: a retrospective observational study
Provision of on-call pharmacist services across public hospitals: a retrospective observational study Open
Objectives To quantify and describe the types of enquiries received by on-call hospital pharmacists across public metropolitan and regional hospitals. Methods A retrospective analysis of data entered by on-call pharmacists between January/…
View article: Simultaneously Dealing With Immortal Time Bias and Residual Confounding: A Case Study of a High‐Dimensional Propensity Score Approach With a Nested Case–Control Framework in Multiple Sclerosis Research
Simultaneously Dealing With Immortal Time Bias and Residual Confounding: A Case Study of a High‐Dimensional Propensity Score Approach With a Nested Case–Control Framework in Multiple Sclerosis Research Open
Background Observational studies of time‐dependent treatments often face immortal time bias and residual confounding, complicating treatment effect estimation. We implemented a high‐dimensional propensity score (hdPS) analysis within a nes…
View article: Cardiovascular Medication and Health Service Use in Individuals With Cancer: A Retrospective Population‐Based Cohort Study
Cardiovascular Medication and Health Service Use in Individuals With Cancer: A Retrospective Population‐Based Cohort Study Open
Background Cancer and cardiovascular disease (CVD) frequently coexist, but little is known about CVD medication use in cancer survivors. The aim of this study was to compare CVD medication and medical service use between individuals with a…
View article: Evaluating the Role of High‐Dimensional Proxy Data in Confounding Adjustment in Multiple Sclerosis Research: A Case Study
Evaluating the Role of High‐Dimensional Proxy Data in Confounding Adjustment in Multiple Sclerosis Research: A Case Study Open
Purpose Given the historical use of limited confounders in multiple sclerosis (MS) studies utilizing administrative health data, this brief report evaluates the impact of incorporating high‐dimensional proxy information on confounder adjus…
View article: Comorbidity patterns and mortality in atrial fibrillation: a latent class analysis of the EURopean study of Older Subjects with Atrial Fibrillation (EUROSAF)
Comorbidity patterns and mortality in atrial fibrillation: a latent class analysis of the EURopean study of Older Subjects with Atrial Fibrillation (EUROSAF) Open
We observed an association between comorbidity phenotypes identified using LCA and mortality in older AF patients. Further research is warranted to identify the mechanisms underpinning such associations.
View article: Risk of cardiovascular and autoimmune disease in people with multiple sclerosis on long-term interferon-β therapy
Risk of cardiovascular and autoimmune disease in people with multiple sclerosis on long-term interferon-β therapy Open
Chronically elevated type I interferons (−β and -α) can induce atherosclerosis and autoimmunity but whether this link translates into adverse events in interferon-β users with multiple sclerosis is unknown. We therefore aimed to determine …
View article: Cardiovascular mortality in people with cancer compared to the general population: A systematic review and meta‐analysis
Cardiovascular mortality in people with cancer compared to the general population: A systematic review and meta‐analysis Open
Background Cardiovascular disease (CVD) is the leading cause of non‐cancer death in cancer survivors, but the risk of CVD varies between cancers. Objectives To synthesise available evidence on patterns and magnitude of CVD mortality risk. …
View article: Pre-Frailty and Frailty in Hospitalized Older Adults: A Comparison Study in People with and without a History of Cancer in an Acute Medical Unit
Pre-Frailty and Frailty in Hospitalized Older Adults: A Comparison Study in People with and without a History of Cancer in an Acute Medical Unit Open
A prospective observational study was conducted in a cohort of older adults ≥65 years (n = 329), admitted to the acute medical unit (AMU) of a tertiary hospital, to describe and compare characteristics including frailty status and clinical…
View article: Adverse Events Associated With Disease-Modifying Drugs for Multiple Sclerosis
Adverse Events Associated With Disease-Modifying Drugs for Multiple Sclerosis Open
This study provides Class III evidence that for patients with MS, while DMD exposure reduces the risk of infection-related hospitalizations, there are increased risks of infection-related physician visits and incident adverse events for se…
View article: Multiple sclerosis disease-modifying drug use by immigrants: a real-world study
Multiple sclerosis disease-modifying drug use by immigrants: a real-world study Open
Little is known about disease-modifying drug (DMD) initiation by immigrants with multiple sclerosis (MS) in countries with universal health coverage. We assessed the association between immigration status and DMD use within 5-years after t…
View article: Patterns of mental health service utilisation in people with cancer compared with people without cancer: analysis of the Australian National Study of Mental Health and Wellbeing
Patterns of mental health service utilisation in people with cancer compared with people without cancer: analysis of the Australian National Study of Mental Health and Wellbeing Open
Purpose To compare the patterns of mental health service utilisation between people with and without cancer. Methods We performed a cross-sectional study using data of all respondents aged ≥ 25 years from the Australian National Study of M…
View article: Health status and mental distress in people with cancer and comorbid conditions: The Australian National Health Survey analysis
Health status and mental distress in people with cancer and comorbid conditions: The Australian National Health Survey analysis Open
Introduction Data on the impact of specific comorbidities on health outcomes is limited. We compared health status and mental distress between individuals with and without cancer according to comorbidity type. Methods A cross‐sectional ana…
View article: Polypharmacy and multiple sclerosis: A population-based study
Polypharmacy and multiple sclerosis: A population-based study Open
Background: Little is known about polypharmacy and multiple sclerosis (MS). Objectives: To estimate polypharmacy prevalence in a population-based MS cohort and compare persons with/without polypharmacy. Methods: Using administrative and ph…
View article: Disease-Modifying Drugs for Multiple Sclerosis and Association With Survival
Disease-Modifying Drugs for Multiple Sclerosis and Association With Survival Open
Our study demonstrates an association between the DMDs for MS and improved survival in the real-world setting.
View article: Emergency department use by persons with MS: A population-based descriptive study with a focus on infection-related visits
Emergency department use by persons with MS: A population-based descriptive study with a focus on infection-related visits Open
We described emergency department (ED) visits (all visits and infection-related) by persons with multiple sclerosis (MS) in British Columbia, Canada (1 April 2012 to 31 December 2017). We identified 15,350 MS cases using health administrat…
View article: Women's Health in Multiple Sclerosis: A Scoping Review
Women's Health in Multiple Sclerosis: A Scoping Review Open
Background Women with multiple sclerosis (MS) may face challenges related to managing reproduction, pregnancy, and menopause while simultaneously managing their disease. The purpose of this scoping review was to map the literature broadly …
View article: Disease-Modifying Drug Uptake and Health Service Use in the Ageing MS Population
Disease-Modifying Drug Uptake and Health Service Use in the Ageing MS Population Open
Background Evidence regarding the efficacy or effectiveness of the disease-modifying drugs (DMDs) in the older multiple sclerosis (MS) population is scarce. This has contributed to a lack of evidence-based treatment recommendations for the…
View article: Disease-modifying drugs for multiple sclerosis and subsequent health service use
Disease-modifying drugs for multiple sclerosis and subsequent health service use Open
Objective: We assessed the relationship between the multiple sclerosis (MS) disease-modifying drugs (DMDs) and healthcare use. Methods: Persons with MS (aged ⩾18 years) were identified using linked population-based health administrative da…
View article: MSJ910500_supplemental_table_2 – Supplemental material for Adherence to laboratory monitoring among people taking oral drugs for multiple sclerosis: A Canadian population-based study
MSJ910500_supplemental_table_2 – Supplemental material for Adherence to laboratory monitoring among people taking oral drugs for multiple sclerosis: A Canadian population-based study Open
Supplemental material, MSJ910500_supplemental_table_2 for Adherence to laboratory monitoring among people taking oral drugs for multiple sclerosis: A Canadian population-based study by Huah Shin Ng, Elaine Kingwell, Feng Zhu, Tingting Zhan…
View article: Patterns of health service utilisation among the Australian population with cancer compared to the general population
Patterns of health service utilisation among the Australian population with cancer compared to the general population Open
Aim: To evaluate patterns of health service utilisation among the Australian population with cancer compared with the general population.\n\nMethods: Data for all the respondents aged 25 years and above from two successive Australian Natio…
View article: Incidence of Comorbidities in Women with Breast Cancer Treated with Tamoxifen or an Aromatase Inhibitor: An Australian Population-Based Cohort Study
Incidence of Comorbidities in Women with Breast Cancer Treated with Tamoxifen or an Aromatase Inhibitor: An Australian Population-Based Cohort Study Open
Background The development of comorbidities has become increasingly relevant with longer-term cancer survival. Objective To assess the pattern of comorbidities among Australian women with breast cancer treated with tamoxifen or an aromatas…
View article: Prognostic factors for mortality due to pneumonia among adults from different age groups in Singapore and mortality predictions based on PSI and CURB-65
Prognostic factors for mortality due to pneumonia among adults from different age groups in Singapore and mortality predictions based on PSI and CURB-65 Open
The predictive effect of prognostic factors for mortality varied among patients with pneumonia from the different age groups. PSI performed significantly better than CURB-65 for mortality prediction, but its discriminative power decreased …