Hsian-Yu Wang
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View article: Comparison of Wound Healing Efficiency Between Bacterial Cellulose Dry Membrane and Commercial Dressings
Comparison of Wound Healing Efficiency Between Bacterial Cellulose Dry Membrane and Commercial Dressings Open
The development of dressing materials mainly protects the wound, prevents infection, and assists in wound healing. Apart from the most common gauze on the market, different dressing materials can accelerate wound healing. Bacterial cellulo…
View article: In Vivo Effect of Halicin on Methicillin-Resistant Staphylococcus aureus-Infected Caenorhabditis elegans and Its Clinical Potential
In Vivo Effect of Halicin on Methicillin-Resistant Staphylococcus aureus-Infected Caenorhabditis elegans and Its Clinical Potential Open
Recently, the high proportion of methicillin-resistant Staphylococcus aureus infections worldwide has highlighted the urgent need for novel antibiotics to combat this crisis. The recent progress in computational techniques for use in healt…
View article: A strategy of novel molecular hydrogen-producing antioxidative auxiliary system improves virus production in cell bioreactor
A strategy of novel molecular hydrogen-producing antioxidative auxiliary system improves virus production in cell bioreactor Open
View article: Oral DNA vaccine adjuvanted with cyclic peptide nanotubes induced a virus-specific antibody response in ducklings against goose parvovirus
Oral DNA vaccine adjuvanted with cyclic peptide nanotubes induced a virus-specific antibody response in ducklings against goose parvovirus Open
A DNA vaccine adjuvanted with cPNTs can effectively express the antigen and can significantly induce an antibody response against goose parvovirus through oral vaccination.
View article: Recombinant hexon protein as a new bovine adenovirus type 3 subunit vaccine candidate
Recombinant hexon protein as a new bovine adenovirus type 3 subunit vaccine candidate Open
Introduction Bovine adenovirus (BAdV) type 3 causes respiratory and gastroenteric diseases of varying severity in cattle, particularly newborn calves. Trials have been conducted of a vaccination against the diseases caused by BAdV using bo…
View article: Oral DNA vaccine adjuvanted with cyclic peptide nanotubes induced a virus-specific antibody response in ducklings against goose parvovirus
Oral DNA vaccine adjuvanted with cyclic peptide nanotubes induced a virus-specific antibody response in ducklings against goose parvovirus Open
Cyclic peptide nanotubes (cPNTs) formed from the spontaneous beta-sheet stacking of peptide rings may serve as a safe and effective oral delivery vehicle/adjuvant for DNA vaccines. In this study, we sought to determine if a DNA vaccine exp…
View article: A Senescence-Like Cellular Response Inhibits Bovine Ephemeral Fever Virus Proliferation
A Senescence-Like Cellular Response Inhibits Bovine Ephemeral Fever Virus Proliferation Open
During industrial-scale production of viruses for vaccine manufacturing, anti-viral response of host cells can dampen maximal viral antigen yield. In addition to interferon responses, many other cellular responses, such as the AMPK signali…
View article: Carbonized Lysine-Nanogels Protect against Infectious Bronchitis Virus
Carbonized Lysine-Nanogels Protect against Infectious Bronchitis Virus Open
In this study, we demonstrate the synthesis of carbonized nanogels (CNGs) from an amino acid (lysine hydrochloride) using a simple pyrolysis method, resulting in effective viral inhibition properties against infectious bronchitis virus (IB…
View article: Activities of imipenem-relebactam combination against carbapenem-nonsusceptible Enterobacteriaceae in Taiwan
Activities of imipenem-relebactam combination against carbapenem-nonsusceptible Enterobacteriaceae in Taiwan Open
Our study supports that imipenem-relebactam is a potential therapy against carbapenem-nonsusceptible Enterobacteriaceae, and to our knowledge, this is the first report of evaluation for imipenem-relebactam efficacy against carbapenem-nonsu…
View article: A senescence-like cellular response inhibits bovine ephemeral fever virus proliferation
A senescence-like cellular response inhibits bovine ephemeral fever virus proliferation Open
During industrial scale production of virus for vaccine manufacturing, antiviral response of host cells can dampen maximal viral antigen yield. In addition to interferon responses, many other cellular responses such as the AMPK signaling p…
View article: N-terminus of Flagellin Fused to an Antigen Improves Vaccine Efficacy against Pasteurella Multocida Infection in Chickens
N-terminus of Flagellin Fused to an Antigen Improves Vaccine Efficacy against Pasteurella Multocida Infection in Chickens Open
Flagellin from bacteria elicits a proinflammatory immune response and may act as a vaccine adjuvant. In this study, we evaluated the adjuvant effect of the N-terminus of flagellin (residues 1–99) when linked to an antigen (a truncated, con…
View article: Evaluation of long-term antibody response and cross-serotype reaction in ducks immunised with recombinant <i>Riemerella anatipestifer</i> outer membrane protein A and CpG ODN
Evaluation of long-term antibody response and cross-serotype reaction in ducks immunised with recombinant <i>Riemerella anatipestifer</i> outer membrane protein A and CpG ODN Open
Introduction Riemerella anatipestifer (RA) infections can lead to high mortality in ducklings. Inactivated vaccines against RA are commercially available, but they fail to provide cross-protection against various serotypes. We have previou…
View article: Development of a quick dot blot assay for the titering of bovine ephemeral fever virus
Development of a quick dot blot assay for the titering of bovine ephemeral fever virus Open
View article: Glucocorticoids may compromise the effect of gefitinib in non-small cell lung cancer
Glucocorticoids may compromise the effect of gefitinib in non-small cell lung cancer Open
The epidermal growth factor receptor (EGFR)-targeting tyrosine kinase inhibitors (TKIs) have shown remarkable benefits in non-small cell lung cancer (NSCLC) patients with drug-sensitive mutations in the EGFR gene. Responsive patients are u…
View article: Non-small-cell lung cancer cells combat epidermal growth factor receptor tyrosine kinase inhibition through immediate adhesion-related responses
Non-small-cell lung cancer cells combat epidermal growth factor receptor tyrosine kinase inhibition through immediate adhesion-related responses Open
Results from this study indicate that NSCLC cells can employ the adhesion response as a survival pathway to survive under EGFR-targeted therapy. Simultaneous targeting of EGFR signaling and adhesion pathways would further boost the efficac…