Hyunjoo Pai
YOU?
Author Swipe
View article: Comparison of the Diagnostic Performance of the Central Vein Sign and CSF Oligoclonal Bands Supporting the Diagnosis of Multiple Sclerosis
Comparison of the Diagnostic Performance of the Central Vein Sign and CSF Oligoclonal Bands Supporting the Diagnosis of Multiple Sclerosis Open
Background and ObjectivesThe central vein sign (CVS) describes the presence of venules within multiple sclerosis (MS) brain lesions, visible on T2*-weighted MRI. In the upcoming revision of the MS diagnostic criteria, the simplified “rule …
View article: P-2216. The characteristics of human microbiome and fecal resistome in patients with recurrent urinary tract infection
P-2216. The characteristics of human microbiome and fecal resistome in patients with recurrent urinary tract infection Open
Background While uropathogenic E. coli (UPEC) is recognized as a primary causative agent of recurrent urinary tract infections (rUTIs), the factors contributing to its colonization remain poorly understood. The study aims to elucidate the …
View article: Presidential address 2025: expansion of computer-based testing from 12 to 27 health professions by 2027 and adoption of a large language model for item generation
Presidential address 2025: expansion of computer-based testing from 12 to 27 health professions by 2027 and adoption of a large language model for item generation Open
View article: What are the perceptions and experiences of adults using mobile applications for self-management in diabetes? A systematic review
What are the perceptions and experiences of adults using mobile applications for self-management in diabetes? A systematic review Open
Objectives Diabetes mellitus is a chronic disease that entails significant burdens to patients, caregivers and society at large. While self-management behaviours like healthy eating and monitoring of blood glucose help to reduce the care b…
View article: Attributable Costs of <i>Clostridioides difficile</i> Infections in Korea
Attributable Costs of <i>Clostridioides difficile</i> Infections in Korea Open
CDI is associated with substantial healthcare costs in Korea. The economic burden of CDI has gradually increased in South Korea.
View article: Presidential address 2024: the expansion of computer-based testing to numerous health professions licensing examinations in Korea, preparation of computer-based practical tests, and adoption of the medical metaverse
Presidential address 2024: the expansion of computer-based testing to numerous health professions licensing examinations in Korea, preparation of computer-based practical tests, and adoption of the medical metaverse Open
View article: Incidence of <i>Clostridioides difficile</i> Infections in Republic of Korea: A Prospective Study With Active Surveillance vs. National Data From Health Insurance Review & Assessment Service
Incidence of <i>Clostridioides difficile</i> Infections in Republic of Korea: A Prospective Study With Active Surveillance vs. National Data From Health Insurance Review & Assessment Service Open
The incidence of CDI in Korea has been gradually increasing, and its recent value is as high as that in the United State and Europe. CDI is underestimated, particularly in general hospitals in Korea.
View article: Clinical and microbiological characteristics of female patients with acute pyelonephritis who experienced urinary tract infections within the previous year
Clinical and microbiological characteristics of female patients with acute pyelonephritis who experienced urinary tract infections within the previous year Open
The proportion of causative organisms except Escherichia coli was higher in the recurrent group than in the non-recurrent group. Neurogenic bladder and a history of admission or antibiotic use during 1 year prior to inclusion were risk fac…
View article: Comparative analyses of the faecal resistome against β-lactam and quinolone antibiotics in humans and livestock using metagenomic sequencing
Comparative analyses of the faecal resistome against β-lactam and quinolone antibiotics in humans and livestock using metagenomic sequencing Open
View article: 690. Analysis of high-risk antibiotics for Clostridioides difficile infections in Korean hospitals: A nationwide multi-center study
690. Analysis of high-risk antibiotics for Clostridioides difficile infections in Korean hospitals: A nationwide multi-center study Open
Background Clostridioides difficile infection (CDI) is a representative healthcare-associated infection, and the incidence rate continues to increase in Korea. The purpose of this study is to identify antibiotics that are highly related to…
View article: 2518. Lead optimization on 26-membered thiopeptide antibiotics and identification of pre-clinical candidates against <i>Clostridioides difficile</i> and <i>Staphylococcus aureus</i> for impetigo
2518. Lead optimization on 26-membered thiopeptide antibiotics and identification of pre-clinical candidates against <i>Clostridioides difficile</i> and <i>Staphylococcus aureus</i> for impetigo Open
Background Thiopeptides are structurally complex natural products that exert potent antimicrobial activity against Gram-positive pathogens by inhibiting bacterial protein synthesis. However, there has not been any attempt to conduct extens…
View article: Alterations of Handgrip Strength in Type 2 Diabetes Mellitus Patients
Alterations of Handgrip Strength in Type 2 Diabetes Mellitus Patients Open
Background:Peripheral Neuropathy is most prevalent chronic complication in diabetes.Diabetes affect sensory andmotor function including progressive loss of somatosensory sensitivity,Insufficient muscle strength and functionalImpairment.Obj…
View article: Presidential address: improving item validity and adopting computer-based testing, clinical skills assessments, artificial intelligence, and virtual reality in health professions licensing examinations in Korea
Presidential address: improving item validity and adopting computer-based testing, clinical skills assessments, artificial intelligence, and virtual reality in health professions licensing examinations in Korea Open
Progress of health professions licensing examinations in Korea over 31 yearsIn 1992, the Korea Health Personnel Licensing Examination Institute (KHPLEI) was established to provide a national licensing examination system for healthcare prof…
View article: Diversity of binary toxin positive Clostridioides difficile in Korea
Diversity of binary toxin positive Clostridioides difficile in Korea Open
The objective of this study is to determine the trend and diversity of binary toxin-positive Clostridioides difficile over 10 years in Korea. Binary toxin-positive strains were selected from a tertiary hospital in Korea in 2009–2018. The m…
View article: 547. Risk factors that can predict adrenal insufficiency in fever of unknown origin
547. Risk factors that can predict adrenal insufficiency in fever of unknown origin Open
Background Adrenal insufficiency is one of the causes of fever of unknown origin (FUO), however, it is often mistaken for an infectious disease, leading to unnecessary antibiotic use. The purpose of this study is to find out risk factors t…
View article: Different maturation of gut microbiome in Korean children
Different maturation of gut microbiome in Korean children Open
Introduction Gut microbiome plays a crucial role in maintaining human health and is influenced by food intake, age, and other factors. Methods In this study based in Korea, we examined the bacterial taxonomic composition of the gut microbi…
View article: Change in the Perception of Oral Antibiotics Among Medical Students After Participating in a Parenteral-to-Oral Conversion Program for Highly Bioavailable Antibiotics
Change in the Perception of Oral Antibiotics Among Medical Students After Participating in a Parenteral-to-Oral Conversion Program for Highly Bioavailable Antibiotics Open
Background Appropriate conversion of antibiotics from a parenteral to the oral route can lower the risk of catheter-associated infections, reduce medical costs, and shorten hospitalization. This study investigated the effect of a parentera…
View article: Deciphering Resistome in Patients With Chronic Obstructive Pulmonary Diseases and Clostridioides difficile Infections
Deciphering Resistome in Patients With Chronic Obstructive Pulmonary Diseases and Clostridioides difficile Infections Open
Antibiotics alter the gut microbiome and cause dysbiosis leading to antibiotic-resistant organisms. Different patterns of antibiotic administration cause a difference in bacterial composition and resistome in the human gut. We comprehensiv…
View article: Gut Microbiome of <i>Clostridioides difficile</i> Patients
Gut Microbiome of <i>Clostridioides difficile</i> Patients Open
View article: Relationship between the appropriateness of antibiotic treatment and clinical outcomes/medical costs of patients with community-acquired acute pyelonephritis: a multicenter prospective cohort study
Relationship between the appropriateness of antibiotic treatment and clinical outcomes/medical costs of patients with community-acquired acute pyelonephritis: a multicenter prospective cohort study Open
View article: Changes in the characteristics of community-onset fluoroquinolone-resistant Escherichia coli isolates causing community-acquired acute pyelonephritis in South Korea
Changes in the characteristics of community-onset fluoroquinolone-resistant Escherichia coli isolates causing community-acquired acute pyelonephritis in South Korea Open
Among uropathogenic FQ-R E. coli isolates in South Korea, the prevalence of ST131 and the proportion of isolates containing ESBL and/or PMQR determinants have increased.
View article: Which is the Preferred Regimen for Non-Severe <i>Clostridioides difficile</i> Infection in Korea, Vancomycin or Metronidazole?
Which is the Preferred Regimen for Non-Severe <i>Clostridioides difficile</i> Infection in Korea, Vancomycin or Metronidazole? Open
The emergence of hypervirulent Clostridioides difficile strains has decreased the efficacy of metronidazole in the treatment of C. difficile infection (CDI). Therefore, revised guidelines no longer recommend the use of metron…
View article: Quantitative Evaluation of the Economic Impact of Antimicrobial Resistance on the Treatment of Community-Acquired Acute Pyelonephritis in Korea
Quantitative Evaluation of the Economic Impact of Antimicrobial Resistance on the Treatment of Community-Acquired Acute Pyelonephritis in Korea Open
Patients with community-acquired APN with ESBL-producing Enterobacteriale as the causative pathogen would incur, on average, 27.0% higher medical costs and 22.0% longer hospitalization days than patients detected with non-ESBL-producing pa…
View article: A Case of Syphilitic Colitis Presenting as Acute Abdomen in a Non-HIV Adult
A Case of Syphilitic Colitis Presenting as Acute Abdomen in a Non-HIV Adult Open
View article: Genetic Relatedness of 5-Year Isolates of Clostridioides difficile Polymerase Chain Reaction Ribotype 017 Strains in a Hospital
Genetic Relatedness of 5-Year Isolates of Clostridioides difficile Polymerase Chain Reaction Ribotype 017 Strains in a Hospital Open
The objective of this study was to analyse the genetic relatedness of Clostridioides difficile polymerase chain reaction ribotype 017 (RT017) strains from patients with hospital-acquired C. difficile infection (HA-CDI) in a hospital with a…
View article: Relationship Between The Appropriateness of Antibiotic Treatment and Clinical Outcomes of Patients With Community-Acquired Acute Pyelonephritis: A Multicenter Prospective Cohort Study
Relationship Between The Appropriateness of Antibiotic Treatment and Clinical Outcomes of Patients With Community-Acquired Acute Pyelonephritis: A Multicenter Prospective Cohort Study Open
Background Inappropriate use of antibiotics not only increases antibiotic resistance as collateral damage but also increases clinical failure rates and medical costs. The purpose of this study was to determine the relationship between the …
View article: Differences in the Clinical Outcome of Community-Acquired APN According to the Appropriateness of Antibiotic Use
Differences in the Clinical Outcome of Community-Acquired APN According to the Appropriateness of Antibiotic Use Open
Background: The purpose of this study was to find out the relationship between appropriateness of antibiotic prescription and clinical outcomes in patients with community-acquired acute pyelonephritis (CA-APN). Methods: A multicenter prosp…
View article: High fecal carriage of blaCTX-M, blaCMY-2, and plasmid-mediated quinolone resistance genes among healthy Korean people in a metagenomic analysis
High fecal carriage of blaCTX-M, blaCMY-2, and plasmid-mediated quinolone resistance genes among healthy Korean people in a metagenomic analysis Open
View article: What is the optimal antibiotic treatment strategy for carbapenem-resistant Acinetobacter baumannii (CRAB)? A multicentre study in Korea
What is the optimal antibiotic treatment strategy for carbapenem-resistant Acinetobacter baumannii (CRAB)? A multicentre study in Korea Open
A combination of colistin and carbapenem and sulbactam-containing regimen may contribute improved mortality in CRAB infections. Colistin monotherapy should be considered cautiously in severe CRAB infections or CRAB pneumonia. A minocycline…
View article: Fluoroquinolone Can Be an Effective Treatment Option for Acute Pyelonephritis When the Minimum Inhibitory Concentration of Levofloxacin for the Causative Escherichia coli Is ≤16 mg/L
Fluoroquinolone Can Be an Effective Treatment Option for Acute Pyelonephritis When the Minimum Inhibitory Concentration of Levofloxacin for the Causative Escherichia coli Is ≤16 mg/L Open
The purpose of this study was to determine whether the fluoroquinolone (FQ) minimum inhibitory concentration (MIC) for the causative agent Escherichia coli influences the clinical response of FQ treatment at 72 h in patients with community…