Huadan Xue
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View article: Total tumor apparent diffusion coefficient histogram analysis of whole-body DWI-MRI for prognostic stratification in patients with R-ISS stage II multiple myeloma
Total tumor apparent diffusion coefficient histogram analysis of whole-body DWI-MRI for prognostic stratification in patients with R-ISS stage II multiple myeloma Open
The median ttADC of whole-body DWI-MRI is an independent predictor of OS in R-ISS II MM patients, suggesting its potential role in further prognostic stratification in this patients' subgroup.
View article: Machine Learning‐Based Radiomics in Malignancy Prediction of Pancreatic Cystic Lesions: Evidence from Cyst Fluid Multi‐Omics
Machine Learning‐Based Radiomics in Malignancy Prediction of Pancreatic Cystic Lesions: Evidence from Cyst Fluid Multi‐Omics Open
The malignant potential of pancreatic cystic lesions (PCLs) varies dramatically, leading to difficulties when making clinical decisions. This study aimed to develop noninvasive clinical‐radiomic models using preoperative CT images to predi…
View article: Combined immune-peptide nanofiber with HSP70/AKT/mTOR axis blockade enhances near-infrared photoimmunotherapy, inhibiting tumor growth and recurrence
Combined immune-peptide nanofiber with HSP70/AKT/mTOR axis blockade enhances near-infrared photoimmunotherapy, inhibiting tumor growth and recurrence Open
Although immune checkpoint blockade (ICB) therapies have shown clinical benefit, ICB remains limited effect on most “immune-cold” solid tumors, i.e., tumors with low immune infiltration. Near-infrared photoimmunotherapy (NIR-PIT) converts …
View article: Damage evaluation of craniofacial localized scleroderma using magnetic resonance imaging
Damage evaluation of craniofacial localized scleroderma using magnetic resonance imaging Open
MRI can reliably quantify damage in craniofacial LoS, and may serve as a useful and objective tool for overall craniofacial LoS evaluation.
View article: Semi-Supervised Medical Image Segmentation with Cross-View Consistency and Contrastive Learning
Semi-Supervised Medical Image Segmentation with Cross-View Consistency and Contrastive Learning Open
View article: Advancing Rectal MRI Segmentation with Clip-Driven Semi-Supervised Learning and Semantic Alignment
Advancing Rectal MRI Segmentation with Clip-Driven Semi-Supervised Learning and Semantic Alignment Open
View article: Comparison of CapeOX versus Single-Agent Capecitabine in Neoadjuvant Chemoradiotherapy for High-Risk Locally Advanced Rectal Cancer: Long-Term Results from the MONT-R Multicenter Randomized Controlled Trial
Comparison of CapeOX versus Single-Agent Capecitabine in Neoadjuvant Chemoradiotherapy for High-Risk Locally Advanced Rectal Cancer: Long-Term Results from the MONT-R Multicenter Randomized Controlled Trial Open
View article: Establishment of Surgical Difficulty Grading System and Application of MRI-Based Artificial Intelligence to Stratify Difficulty in Laparoscopic Rectal Surgery
Establishment of Surgical Difficulty Grading System and Application of MRI-Based Artificial Intelligence to Stratify Difficulty in Laparoscopic Rectal Surgery Open
(1) Background: The difficulty of pelvic operation is greatly affected by anatomical constraints. Defining this difficulty and assessing it based on conventional methods has some limitations. Artificial intelligence (AI) has enabled rapid …
View article: Pancreatic cancer with ovarian metastasis: cases report and literature review
Pancreatic cancer with ovarian metastasis: cases report and literature review Open
Background: Pancreatic cancer with ovarian metastases is rare and easily misdiagnosed. Patients with ovarian metastases are first diagnosed with ovarian cancer and may miss the opportunity to receive surgical operation. We report 7 rare ca…
View article: A single-center experience on endoscopic ultrasonography-guided ethanol ablation of insulinomas
A single-center experience on endoscopic ultrasonography-guided ethanol ablation of insulinomas Open
For patients who are not suitable for surgical resections, endoscopic ultrasonography-guided ethanol ablation of insulinomas could be an effective and safe alternative to relieve symptoms of hypoglycemia.
View article: Optical magnetic multimodality imaging of plectin-1-targeted imaging agent for the precise detection of orthotopic pancreatic ductal adenocarcinoma in mice
Optical magnetic multimodality imaging of plectin-1-targeted imaging agent for the precise detection of orthotopic pancreatic ductal adenocarcinoma in mice Open
View article: Systemic Therapy for Hepatocellular Carcinoma: Chinese Consensus-Based Interdisciplinary Expert Statements
Systemic Therapy for Hepatocellular Carcinoma: Chinese Consensus-Based Interdisciplinary Expert Statements Open
Background: Hepatocellular carcinoma (HCC) is the most common type of liver cancer and causes many cancer-related deaths worldwide; in China, it is the second most prevalent cause of cancer deaths. Most patients are diagnosed…
View article: Assessment of Changes in the Cesarean Scar and Uterus Between One and Two Years after Cesarean Section Using 3D T2w SPACE MRI
Assessment of Changes in the Cesarean Scar and Uterus Between One and Two Years after Cesarean Section Using 3D T2w SPACE MRI Open
Objective To evaluate changes in morphology of the cesarean scar and uterus between one and two years after cesarean section using high-resolution, three dimensional T2-weighted sampling perfection with application optimized contrast using…
View article: Development of a Prognostic Nomogram in Hepatocellular Carcinoma with Portal Vein Tumor Thrombus Following Trans-Arterial Chemoembolization with Drug-Eluting Beads
Development of a Prognostic Nomogram in Hepatocellular Carcinoma with Portal Vein Tumor Thrombus Following Trans-Arterial Chemoembolization with Drug-Eluting Beads Open
We developed and validated a nomogram that was accurate and clinically useful in eastern patients with HBV-associated HCC with PVTT who underwent DEB-TACE.
View article: Assessment of Response to Chemotherapy in Pancreatic Cancer with Liver Metastasis: CT Texture as a Predictive Biomarker
Assessment of Response to Chemotherapy in Pancreatic Cancer with Liver Metastasis: CT Texture as a Predictive Biomarker Open
In this paper, we assess changes in CT texture of metastatic liver lesions after treatment with chemotherapy in patients with pancreatic cancer and determine if texture parameters correlate with measured time to progression (TTP). This ret…
View article: Imaging Features of Breast Periductal Stromal Tumor: A Case Report
Imaging Features of Breast Periductal Stromal Tumor: A Case Report Open
Breast periductal stromal tumor (PDST) is a rare biphasic tumor, with both benign ductal epithelium and non-phyllodes sarcomatous stroma. Its imaging features were rarely reported due to the rarity. In this study, we describe the case of a…
View article: Design of the Shunyi study on cardiovascular disease and age-related brain changes: a community-based, prospective, cohort study
Design of the Shunyi study on cardiovascular disease and age-related brain changes: a community-based, prospective, cohort study Open
With an extensive range of clinical, genetic, and imaging data, the Shunyi cohort study has the potential to contribute significantly towards identifying the causes and consequences of cardiovascular disease and age-related brain changes i…
View article: Human and mouse studies establish TBX6 in Mendelian CAKUT and as a potential driver of kidney defects associated with the 16p11.2 microdeletion syndrome
Human and mouse studies establish TBX6 in Mendelian CAKUT and as a potential driver of kidney defects associated with the 16p11.2 microdeletion syndrome Open
View article: Progress and prospect on imaging diagnosis of COVID-19
Progress and prospect on imaging diagnosis of COVID-19 Open
View article: The appropriate position of radiology in COVID-19 diagnosis and treatment—current status and opinion from China
The appropriate position of radiology in COVID-19 diagnosis and treatment—current status and opinion from China Open
View article: Identifying clinical subgroups in IgG4-related disease patients using cluster analysis and IgG4-RD composite score
Identifying clinical subgroups in IgG4-related disease patients using cluster analysis and IgG4-RD composite score Open
Background To explore the clinical patterns of patients with IgG4-related disease (IgG4-RD) based on laboratory tests and the number of organs involved. Methods Twenty-two baseline variables were obtained from 154 patients with IgG4-RD. Ba…
View article: Tumor microenvironment-oriented adaptive nanodrugs based on peptide self-assembly
Tumor microenvironment-oriented adaptive nanodrugs based on peptide self-assembly Open
The tumor microenvironment is of significance to promote release or reorganization of peptide-modulated nanodrugs, optimizing drug bioavailability and therapeutic outcome.
View article: Combination Immunotherapy with Cytotoxic T-Lymphocyte–Associated Antigen-4 and Programmed Death Protein-1 Inhibitors Prevents Postoperative Breast Tumor Recurrence and Metastasis
Combination Immunotherapy with Cytotoxic T-Lymphocyte–Associated Antigen-4 and Programmed Death Protein-1 Inhibitors Prevents Postoperative Breast Tumor Recurrence and Metastasis Open
Postoperative tumor recurrence and metastasis remain an extreme challenge in breast cancer. Therapies that target cytotoxic T-lymphocyte–associated antigen 4 (CTLA-4) and programmed cell death protein 1 (PD-1) have provided unprecedented c…
View article: Parallel Medical Imaging for Intelligent Medical Image Analysis: Concepts, Methods, and Applications
Parallel Medical Imaging for Intelligent Medical Image Analysis: Concepts, Methods, and Applications Open
There has been much progress in data-driven artificial intelligence technology for medical image analysis in the last decades. However, it still remains challenging due to its distinctive complexity of acquiring and annotating image data, …
View article: Differences and similarities between IgG4-related disease with and without dacryoadenitis and sialoadenitis: clinical manifestations and treatment efficacy
Differences and similarities between IgG4-related disease with and without dacryoadenitis and sialoadenitis: clinical manifestations and treatment efficacy Open
View article: Laparoscopic resection of large retrorectal developmental cysts in adults: Single-centre experiences of 20 cases
Laparoscopic resection of large retrorectal developmental cysts in adults: Single-centre experiences of 20 cases Open
The laparoscopic approach can provide a feasible and effective alternative for large RRDCs, with advantages of the minimally invasive surgery. For lesions with ultra-low caudal ends, especially those closely clinging to the rectum, a combi…
View article: A novel approach to monitoring the efficacy of anti-tumor treatments in animal models: combining functional MRI and texture analysis
A novel approach to monitoring the efficacy of anti-tumor treatments in animal models: combining functional MRI and texture analysis Open
All these results suggest some strong correlations among DWI, DCE and texture analysis, which are beneficial for further study and clinical research.
View article: PD-1 blockade in combination with zoledronic acid to enhance the antitumor efficacy in the breast cancer mouse model
PD-1 blockade in combination with zoledronic acid to enhance the antitumor efficacy in the breast cancer mouse model Open
Our study provides preclinical evidence for the enhanced BC treatment benefit through targeting co-signal molecules by combining anti-PD-1 antibody plus ZA treatment.
View article: Spleen and splenic vascular involvement in acute pancreatitis: an MRI study
Spleen and splenic vascular involvement in acute pancreatitis: an MRI study Open
Background: To investigate the spleen and splenic vascular involvement in acute pancreatitis (AP) and their correlations with the severity of AP using magnetic resonance imaging (MRI). Methods: MRI of 239 patients with AP was retrospective…
View article: Improved resection and prolonged overall survival with PD-1-IRDye800CW fluorescence probe-guided surgery and PD-1 adjuvant immunotherapy in 4T1 mouse model
Improved resection and prolonged overall survival with PD-1-IRDye800CW fluorescence probe-guided surgery and PD-1 adjuvant immunotherapy in 4T1 mouse model Open
An intraoperative technique to accurately identify microscopic tumor residuals could decrease the risk of positive surgical margins. Several lines of evidence support the expression and immunotherapeutic effect of PD-1 in breast cancer. He…