Huaixing Li
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View article: Interethnic analyses of blood pressure loci in populations of East Asian and European descent
Interethnic analyses of blood pressure loci in populations of East Asian and European descent Open
View article: <strong>Diet-related Lipidomic Signatures and Changed Type 2 Diabetes Risk in A Randomized Controlled Feeding Study with Mediterranean Diet and Traditional Chinese or Transitional diets</strong>
<strong>Diet-related Lipidomic Signatures and Changed Type 2 Diabetes Risk in A Randomized Controlled Feeding Study with Mediterranean Diet and Traditional Chinese or Transitional diets</strong> Open
Objective: Few trials studied the links of food components in different diets with their induced lipidomic changes and related metabolic outcomes. Thus, we investigated specific lipidomic signatures with habitual diets and…
View article: <strong>Diet-related Lipidomic Signatures and Changed Type 2 Diabetes Risk in A Randomized Controlled Feeding Study with Mediterranean Diet and Traditional Chinese or Transitional diets</strong>
<strong>Diet-related Lipidomic Signatures and Changed Type 2 Diabetes Risk in A Randomized Controlled Feeding Study with Mediterranean Diet and Traditional Chinese or Transitional diets</strong> Open
Objective: Few trials studied the links of food components in different diets with their induced lipidomic changes and related metabolic outcomes. Thus, we investigated specific lipidomic signatures with habitual diets and…
View article: Diet-Related Lipidomic Signatures and Changed Type 2 Diabetes Risk in a Randomized Controlled Feeding Study With Mediterranean Diet and Traditional Chinese or Transitional Diets
Diet-Related Lipidomic Signatures and Changed Type 2 Diabetes Risk in a Randomized Controlled Feeding Study With Mediterranean Diet and Traditional Chinese or Transitional Diets Open
OBJECTIVE Few trials studied the links of food components in different diets with their induced lipidomic changes and related metabolic outcomes. Thus, we investigated specific lipidomic signatures with habitual diets and modified diabetes…
View article: Association of omega 3 polyunsaturated fatty acids with incident chronic kidney disease: pooled analysis of 19 cohorts
Association of omega 3 polyunsaturated fatty acids with incident chronic kidney disease: pooled analysis of 19 cohorts Open
Objective To assess the prospective associations of circulating levels of omega 3 polyunsaturated fatty acid (n-3 PUFA) biomarkers (including plant derived α linolenic acid and seafood derived eicosapentaenoic acid, docosapentaenoic acid, …
View article: Water-immersion softening mechanism of coal rock mass based on split Hopkinson pressure bar experiment
Water-immersion softening mechanism of coal rock mass based on split Hopkinson pressure bar experiment Open
The coal mining process is affected by various water sources such as groundwater and coal seam water injection. Understanding the dynamic mechanical parameters of water-immersed coal is helpful for coalmine safe production. The impact comp…
View article: Isocaloric-restricted Mediterranean Diet and Chinese Diets High or Low in Plants in Adults With Prediabetes
Isocaloric-restricted Mediterranean Diet and Chinese Diets High or Low in Plants in Adults With Prediabetes Open
Context Calorie restriction plus dietary advice is suggested as a preventive strategy for individuals with obesity and prediabetes; however, optimal diet is still debatable. We aimed to compare the effects of Mediterranean diet (MD) and Ch…
View article: Experimental study on preparation of nanoparticle-surfactant nanofluids and their effects on coal surface wettability
Experimental study on preparation of nanoparticle-surfactant nanofluids and their effects on coal surface wettability Open
To improve the efficiency of coal seam water injection, the influence of nanofluids on coal surface wettability was studied based on the nano drag reduction and injection enhancement technology in the field of tertiary oil recovery. The co…
View article: Change Law of Lower Limit of Gas Explosion at Ultra-High Temperatures
Change Law of Lower Limit of Gas Explosion at Ultra-High Temperatures Open
During coal seam mining, a large amount of low-concentration mine gas will be produced, and it is the main utilization way to pass it into a thermal storage oxidation device to obtain heat energy. The thermal storage oxidation process is c…
View article: Studies on Gas Seepage Characteristics in Different Stress Zones of Bottom Coal in Steeply Inclined and Extra-Thick Coal Seams under Mining Action
Studies on Gas Seepage Characteristics in Different Stress Zones of Bottom Coal in Steeply Inclined and Extra-Thick Coal Seams under Mining Action Open
The gas released from the bottom coal of the horizontal slicing mining face in steeply inclined and extra-thick coal seams seriously threatens the safety of the upper slicing mining face. To explore the seepage characteristics of bottom co…
View article: Research On Water-Immersion Softening Mechanism of Coal Rock Mass Based on Split Hopkinson Pressure Bar Experiment
Research On Water-Immersion Softening Mechanism of Coal Rock Mass Based on Split Hopkinson Pressure Bar Experiment Open
The coal mining process is affected by multiple sources of water such as groundwater and coal seam water injection. Understanding the dynamic mechanical parameters of water-immersed coal is helpful to the safe production of coal mines. The…
View article: Global Dynamics of an SEIR Model with the Age of Infection and Vaccination
Global Dynamics of an SEIR Model with the Age of Infection and Vaccination Open
This paper is concerned with the stability of a SEIR (susceptible-exposed-infectious-recovered) model with the age of infection and vaccination. Firstly, we prove the positivity, boundedness, and asymptotic smoothness of the solutions. Nex…
View article: Meta-analysis of genome-wide association studies in East Asian-ancestry populations identifies four new loci for body mass index
Meta-analysis of genome-wide association studies in East Asian-ancestry populations identifies four new loci for body mass index Open
Recent genetic association studies have identified 55 genetic loci associated with obesity or body mass index (BMI). The vast majority, 51 loci, however, were identified in European-ancestry populations. We conducted a meta-analysis of ass…
View article: Changes in Plasma Metabolome Profiles Following Oral Glucose Challenge among Adult Chinese
Changes in Plasma Metabolome Profiles Following Oral Glucose Challenge among Adult Chinese Open
Little is known about changes in plasma metabolome profiles during the oral glucose tolerance test (OGTT) in Chinese. We aimed to characterize plasma metabolomic profiles at 0 and 2 h of OGTT and their changes in individuals of different g…
View article: Circulating Glycerolipids, Fatty Liver Index, and Incidence of Type 2 Diabetes: A Prospective Study Among Chinese
Circulating Glycerolipids, Fatty Liver Index, and Incidence of Type 2 Diabetes: A Prospective Study Among Chinese Open
Context Few lipidomic studies have specifically investigated the association of circulating glycerolipids and type 2 diabetes (T2D) risk, especially among Asian populations. It remains unknown whether or to what degree fatty liver could ex…
View article: Associations among circulating sphingolipids, β-cell function, and risk of developing type 2 diabetes: A population-based cohort study in China
Associations among circulating sphingolipids, β-cell function, and risk of developing type 2 diabetes: A population-based cohort study in China Open
Background Animal studies suggest vital roles of sphingolipids, especially ceramides, in the pathogenesis of type 2 diabetes (T2D) via pathways involved in insulin resistance, β-cell dysfunction, and inflammation, but human studies are lim…
View article: A meta-analysis of genome-wide association studies for adiponectin levels in East Asians identifies a novel locus near WDR11-FGFR2
A meta-analysis of genome-wide association studies for adiponectin levels in East Asians identifies a novel locus near WDR11-FGFR2 Open
Blood levels of adiponectin, an adipocyte-secreted protein correlated with metabolic and cardiovascular risks, are highly heritable. Genome-wide association (GWA) studies for adiponectin levels have identified 14 loci harboring variants as…
View article: Replacing white rice bars with peanuts as snacks in the habitual diet improves metabolic syndrome risk among Chinese adults: a randomized controlled trial
Replacing white rice bars with peanuts as snacks in the habitual diet improves metabolic syndrome risk among Chinese adults: a randomized controlled trial Open
View article: Effects of Briquettes with Different Crack Structures on Propagation Characteristics of Ultrasonic Waves under Wetting Conditions
Effects of Briquettes with Different Crack Structures on Propagation Characteristics of Ultrasonic Waves under Wetting Conditions Open
In order to examine the effect of briquettes with different crack structures on ultrasonic characteristics under different wetting conditions, a series of ultrasonic testing are carried out on briquettes at different wetting heights and th…
View article: Genetic susceptibility, dietary cholesterol intake, and plasma cholesterol levels in a Chinese population
Genetic susceptibility, dietary cholesterol intake, and plasma cholesterol levels in a Chinese population Open
View article: Genome-wide association studies in East Asians identify new loci for waist-hip ratio and waist circumference
Genome-wide association studies in East Asians identify new loci for waist-hip ratio and waist circumference Open
Sixty genetic loci associated with abdominal obesity, measured by waist circumference (WC) and waist-hip ratio (WHR), have been previously identified, primarily from studies conducted in European-ancestry populations. We conducted a meta-a…
View article: Association analyses of East Asian individuals and trans-ancestry analyses with European individuals reveal new loci associated with cholesterol and triglyceride levels
Association analyses of East Asian individuals and trans-ancestry analyses with European individuals reveal new loci associated with cholesterol and triglyceride levels Open
Large-scale meta-analyses of genome-wide association studies (GWAS) have identified >175 loci associated with fasting cholesterol levels, including total cholesterol (TC), high-density lipoprotein cholesterol (HDL-C), low-density lipoprote…
View article: Erythrocyte PUFAs, circulating acylcarnitines, and metabolic syndrome risk: a prospective study in Chinese
Erythrocyte PUFAs, circulating acylcarnitines, and metabolic syndrome risk: a prospective study in Chinese Open
The effects of PUFAs on metabolic syndrome (MetS) remain to be characterized, particularly in Asians. We aimed to investigate the prospective associations of PUFAs with MetS and the role of acylcarnitines in these associations in Chinese i…
View article: Interethnic analyses of blood pressure loci in populations of East Asian and European descent
Interethnic analyses of blood pressure loci in populations of East Asian and European descent Open
Blood pressure (BP) is a major risk factor for cardiovascular disease and more than 200 genetic loci associated with BP are known. Here, we perform a multi-stage genome-wide association study for BP (max N = 289,038) principally in East As…
View article: Refining the accuracy of validated target identification through coding variant fine-mapping in type 2 diabetes
Refining the accuracy of validated target identification through coding variant fine-mapping in type 2 diabetes Open
View article: Associations of Plasma Amino Acid and Acylcarnitine Profiles with Incident Reduced Glomerular Filtration Rate
Associations of Plasma Amino Acid and Acylcarnitine Profiles with Incident Reduced Glomerular Filtration Rate Open
Background and objectives Metabolomics is instrumental in identifying novel biomarkers of kidney function to aid in the prevention and management of CKD. However, data linking the metabolome to incident eGFR are sparse, particularly in Asi…
View article: Cholecalciferol Supplementation Promotes Bone Turnover in Chinese Adults with Vitamin D Deficiency
Cholecalciferol Supplementation Promotes Bone Turnover in Chinese Adults with Vitamin D Deficiency Open
View article: Correction to: Age at menarche and age at natural menopause in East Asian women: a genome-wide association study
Correction to: Age at menarche and age at natural menopause in East Asian women: a genome-wide association study Open
View article: Exome chip meta-analysis identifies novel loci and East Asian–specific coding variants that contribute to lipid levels and coronary artery disease
Exome chip meta-analysis identifies novel loci and East Asian–specific coding variants that contribute to lipid levels and coronary artery disease Open
View article: Impact of common genetic determinants of Hemoglobin A1c on type 2 diabetes risk and diagnosis in ancestrally diverse populations: A transethnic genome-wide meta-analysis
Impact of common genetic determinants of Hemoglobin A1c on type 2 diabetes risk and diagnosis in ancestrally diverse populations: A transethnic genome-wide meta-analysis Open
BACKGROUND: Glycated hemoglobin (HbA1c) is used to diagnose type 2 diabetes (T2D) and assess glycemic control in patients with diabetes. Previous genome-wide association studies (GWAS) have identified 18 HbA1c-associated genetic variants. …