Hua‐Ling Tsai
YOU?
Author Swipe
View article: Improved outcomes of acute lymphoblastic leukemia after allogeneic blood or marrow transplantation with high-dose post-transplantation cyclophosphamide in the era of more effective pre-transplant therapy
Improved outcomes of acute lymphoblastic leukemia after allogeneic blood or marrow transplantation with high-dose post-transplantation cyclophosphamide in the era of more effective pre-transplant therapy Open
The therapeutic landscape in ALL has changed dramatically over the last decade. Allogeneic blood or marrow transplantation (AlloBMT) has also evolved and remains an important option for consolidation. We assessed the interplay between thes…
View article: Inferred clonal hematopoiesis from tumor DNA sequencing among men with prostate cancer: correlation with somatic tumor alterations and outcomes
Inferred clonal hematopoiesis from tumor DNA sequencing among men with prostate cancer: correlation with somatic tumor alterations and outcomes Open
Background Clonal hematopoiesis (CH) may be inferred from clinical next-generation sequencing (NGS) of tumor tissue. The clinical significance of inferred CH when detected as part of routine tumor sequencing is not well established and it …
View article: A clinicopathologic analysis of 70 patients with mucinous breast carcinoma
A clinicopathologic analysis of 70 patients with mucinous breast carcinoma Open
Purpose: Pure mucinous breast carcinomas (PMBC) are rare cancers that are managed per standard breast cancer treatment protocols. In this study, we review the clinicopathologic features, treatment, and outcomes of patients with PMBC treate…
View article: 604 Clinical and molecular findings from a randomized phase II study of epigenetic priming with azacitidine and entinostat followed by nivolumab in previously treated metastatic non-small cell lung cancer
604 Clinical and molecular findings from a randomized phase II study of epigenetic priming with azacitidine and entinostat followed by nivolumab in previously treated metastatic non-small cell lung cancer Open
Background Epigenetic targeting agents with immunotherapy represents an ongoing combinatorial approach in non-small cell lung cancer (NSCLC). Preclinical studies have shown that histone deacetylase (HDAC) and/or DNA methyltransferase (DNMT…
View article: Data from Targeting Glutamine Metabolism in Breast Cancer with Aminooxyacetate
Data from Targeting Glutamine Metabolism in Breast Cancer with Aminooxyacetate Open
Purpose: Glutamine addiction in c-MYC–overexpressing breast cancer is targeted by the aminotransferase inhibitor, aminooxyacetate (AOA). However, the mechanism of ensuing cell death remains unresolved.Experimental Design: A c…
View article: Data from Targeting Glutamine Metabolism in Breast Cancer with Aminooxyacetate
Data from Targeting Glutamine Metabolism in Breast Cancer with Aminooxyacetate Open
Purpose: Glutamine addiction in c-MYC–overexpressing breast cancer is targeted by the aminotransferase inhibitor, aminooxyacetate (AOA). However, the mechanism of ensuing cell death remains unresolved.Experimental Design: A c…
View article: Supplementary methods and figures S1-S8 from Targeting Glutamine Metabolism in Breast Cancer with Aminooxyacetate
Supplementary methods and figures S1-S8 from Targeting Glutamine Metabolism in Breast Cancer with Aminooxyacetate Open
Supplementary methods and figures S1-S8. (S1): Glutamine dependency and induction of apoptosis on glutamine withdrawal in breast cancer cells. (S2): Cytotoxicity of AOA in breast cancer cells. (S3): Myc regulation of transaminases and glut…
View article: Supplementary methods and figures S1-S8 from Targeting Glutamine Metabolism in Breast Cancer with Aminooxyacetate
Supplementary methods and figures S1-S8 from Targeting Glutamine Metabolism in Breast Cancer with Aminooxyacetate Open
Supplementary methods and figures S1-S8. (S1): Glutamine dependency and induction of apoptosis on glutamine withdrawal in breast cancer cells. (S2): Cytotoxicity of AOA in breast cancer cells. (S3): Myc regulation of transaminases and glut…
View article: Targeting Glutamine Metabolism in Breast Cancer with Aminooxyacetate
Targeting Glutamine Metabolism in Breast Cancer with Aminooxyacetate Open
Purpose: Glutamine addiction in c-MYC–overexpressing breast cancer is targeted by the aminotransferase inhibitor, aminooxyacetate (AOA). However, the mechanism of ensuing cell death remains unresolved. Experimental Design: A correlation be…