Wenhai Huang
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View article: YTHDF2 in Inflammation: Mechanisms and therapeutic strategies
YTHDF2 in Inflammation: Mechanisms and therapeutic strategies Open
View article: Gallstone and bile microbiota: A case-control study based on 16S rRNA gene sequencing
Gallstone and bile microbiota: A case-control study based on 16S rRNA gene sequencing Open
BACKGROUND Gallstone (GS), a prevalent biliary disorder, is associated with bile stasis, infection, and cholesterol metabolism. Recent research highlights the potential role of bile microbiota in GS pathogenesis. This is a case control stu…
View article: Toxicity and Neuroprotective Effect of Suhexiang Pills: A Preclinical Study of a Traditional Compound Preparation for Ischemic Stroke Treatment
Toxicity and Neuroprotective Effect of Suhexiang Pills: A Preclinical Study of a Traditional Compound Preparation for Ischemic Stroke Treatment Open
View article: A hybrid energy-based and AI-based screening approach for the discovery of novel inhibitors of JAK3
A hybrid energy-based and AI-based screening approach for the discovery of novel inhibitors of JAK3 Open
The JAKs protein family is composed of four isoforms, and JAK3 has been regarded as a druggable target for the development of drugs to treat various diseases, including hematologic tumors, cancer, and neuronal death. Therefore, the discove…
View article: The progress of molecules and strategies for the treatment of HBV infection
The progress of molecules and strategies for the treatment of HBV infection Open
Hepatitis B virus infections have always been associated with high levels of mortality. In 2019, hepatitis B virus (HBV)-related diseases resulted in approximately 555,000 deaths globally. In view of its high lethality, the treatment of HB…
View article: Porous La2o2co3 Derived from Solvent-Guided Metal-Organic Frameworks for High-Efficient Phosphorus Removal
Porous La2o2co3 Derived from Solvent-Guided Metal-Organic Frameworks for High-Efficient Phosphorus Removal Open
View article: A Pseudo-Random Signal Generator for Offset Calibration Circuit
A Pseudo-Random Signal Generator for Offset Calibration Circuit Open
A pseudo-random signal generator based on 0.5μm CMOS technology is presented, and it is applied for an auto-zero operational amplifier. The generator circuit includes a linear feedback shift register for generating pseudo-random sequences,…
View article: “Sea Anemone”-like CeFe Oxides for High-Efficient Phosphate Removal
“Sea Anemone”-like CeFe Oxides for High-Efficient Phosphate Removal Open
The excessive release of phosphorus is a prime culprit for eutrophication and algal bloom in the aquatic environment, and there is always an urgent need to develop effective methods to deal with phosphorus pollution. Ce-based oxide is a ty…
View article: A Comparative Study of the Recent Most Potent Small-Molecule PD-L1 Inhibitors: What Can We Learn?
A Comparative Study of the Recent Most Potent Small-Molecule PD-L1 Inhibitors: What Can We Learn? Open
Immune checkpoint inhibitors targeting the PD-1/PD-L1 pathway have become a "game-changer" in the cancer treatment. However, none of the small molecular inhibitors has been approved yet. To explore the advantages and disadvantages of vario…
View article: Corrigendum to “Strontium modulates osteogenic activity of bone cement composed of bioactive borosilicate glass particles by activating Wnt/β-catenin signaling pathway” [Bioact. Mater. 5 (2020) 334–347]
Corrigendum to “Strontium modulates osteogenic activity of bone cement composed of bioactive borosilicate glass particles by activating Wnt/β-catenin signaling pathway” [Bioact. Mater. 5 (2020) 334–347] Open
[This corrects the article DOI: 10.1016/j.bioactmat.2020.02.016.].
View article: Strontium modulates osteogenic activity of bone cement composed of bioactive borosilicate glass particles by activating Wnt/β-catenin signaling pathway
Strontium modulates osteogenic activity of bone cement composed of bioactive borosilicate glass particles by activating Wnt/β-catenin signaling pathway Open
View article: Hypoxia-Mimicking Cobalt-Doped Borosilicate Bioactive Glass Scaffolds with Enhanced Angiogenic and Osteogenic Capacity for Bone Regeneration
Hypoxia-Mimicking Cobalt-Doped Borosilicate Bioactive Glass Scaffolds with Enhanced Angiogenic and Osteogenic Capacity for Bone Regeneration Open
The osteogenic capacity of synthetic bone substitutes is will be highly stimulated by a well-established functional vascularized network. Cobalt (Co) ions are known that can generate a hypoxia-like response and stimulates the production of…
View article: Structural Characteristics of a Family of Bioactive Glasses Formed by Replacing Varying Amounts of SiO <sub>2</sub> in 45S5 Glass with B <sub>2</sub>O <sub>3</sub>
Structural Characteristics of a Family of Bioactive Glasses Formed by Replacing Varying Amounts of SiO <sub>2</sub> in 45S5 Glass with B <sub>2</sub>O <sub>3</sub> Open
View article: Strontium Modulates Osteogenic Activity of Bone Cement Composed of Bioactive Borosilicate Glass Particles by Activating Wnt/Β-Catenin and Bmp Signalling Pathway
Strontium Modulates Osteogenic Activity of Bone Cement Composed of Bioactive Borosilicate Glass Particles by Activating Wnt/Β-Catenin and Bmp Signalling Pathway Open
View article: We the Workers: A Conversation with Huang Wenhai
We the Workers: A Conversation with Huang Wenhai Open
hot over a six-year period (2009)(2010)(2011)(2012)(2013)(2014)(2015) mainly in the industrial heartland of south China-a major hub in the global supply chain-the 2017 film We the Workers (xiongnian zhi pan) follows labour activists as the…
View article: Mesoporous bioactive glass-coated 3D printed borosilicate bioactive glass scaffolds for improving repair of bone defects
Mesoporous bioactive glass-coated 3D printed borosilicate bioactive glass scaffolds for improving repair of bone defects Open
Background: In the field of tissue engineering, there is currently increasing interest in new biomedical materials with high osteogenic ability and comparable mechanical function to repair bone defects. Three-dimensional (3-D) bioac…
View article: Review - bioactive glass implants for potential application in structural bone repair
Review - bioactive glass implants for potential application in structural bone repair Open
Bioactive glass particles andweak scaffolds have been used to heal small contained bone defects but an unmet challenge is the development of bioactive glass implants with the requisite mechanical reliability and in vivo performance to heal…
View article: Enhanced osteointegration of poly(methylmethacrylate) bone cements by incorporating strontium-containing borate bioactive glass
Enhanced osteointegration of poly(methylmethacrylate) bone cements by incorporating strontium-containing borate bioactive glass Open
Although poly(methylmethacrylate) (PMMA) cements are widely used in orthopaedics, they have numerous drawbacks. This study aimed to improve their bioactivity and osseointegration by incorporating strontium-containing borate bioactive glass…
View article: Effect of Gas-foaming Porogen-NaHCO$lt;inf$gt;3$lt;/inf$gt; and Citric Acid on the Properties of Injectable Macroporous Borate Bioactive Glass Cement
Effect of Gas-foaming Porogen-NaHCO$lt;inf$gt;3$lt;/inf$gt; and Citric Acid on the Properties of Injectable Macroporous Borate Bioactive Glass Cement Open
Borate bioactive glass (BBG) is a promising candidate material for bone tissue engineering.Mostly, it was applied in the form of scaffolds and granules.Till now, little work has been done to investigate the fabrication of porous borate bio…
View article: The role of hydrogenotrophic methanogens in an acidogenic reactor
The role of hydrogenotrophic methanogens in an acidogenic reactor Open
Two-phase anaerobic degradation, compared to single-stage anaerobic degradation, has the potential for higher stability, efficiency and biogas production. The acidogenic phase, as the first phase, not only provides the necessary substrate …
View article: Bioactive borate glass promotes the repair of radius segmental bone defects by enhancing the osteogenic differentiation of BMSCs
Bioactive borate glass promotes the repair of radius segmental bone defects by enhancing the osteogenic differentiation of BMSCs Open
Bioactive borate glass (BG) has emerged as a promising alternative for bone regeneration due to its high osteoinductivity, osteoconductivity, compressive strength, and biocompatibility. However, the role of BG in large segmental bone repai…
View article: Bioactive Glass for Large Bone Repair
Bioactive Glass for Large Bone Repair Open
There has been an ongoing quest for new biomedical materials for the repair and regeneration of large segmental bone defects caused by disease or trauma. Autologous bone graft (ABG) remains the gold standard for bone repair despite their l…
View article: Comparison of Borate Bioactive Glass and Calcium Sulfate as Implants for the Local Delivery of Teicoplanin in the Treatment of Methicillin-Resistant Staphylococcus aureus-Induced Osteomyelitis in a Rabbit Model
Comparison of Borate Bioactive Glass and Calcium Sulfate as Implants for the Local Delivery of Teicoplanin in the Treatment of Methicillin-Resistant Staphylococcus aureus-Induced Osteomyelitis in a Rabbit Model Open
There is growing interest in biomaterials that can cure bone infection and also regenerate bone. In this study, two groups of implants composed of 10% (wt/wt) teicoplanin (TEC)-loaded borate bioactive glass (designated TBG) or calcium sulf…
View article: Evaluation of Ti implants coated with Ag-containing borate bioactive glass for simultaneous eradication of infection and fracture fixation in a rabbit tibial model – <b>ERRATUM</b>
Evaluation of Ti implants coated with Ag-containing borate bioactive glass for simultaneous eradication of infection and fracture fixation in a rabbit tibial model – <b>ERRATUM</b> Open