Huanting Li
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View article: Validation and sensitivity analysis of the FLEXPART model using the Kincaid experiment data
Validation and sensitivity analysis of the FLEXPART model using the Kincaid experiment data Open
FLEXPART, a Lagrangian particle dispersion model, is widely used in atmospheric dispersion and nuclear emergency response studies. However, a systematic sensitivity analysis of this model is still lacking. This study, which utilizes meteor…
View article: A Systematic Method for the Identification of Oligosaccharide Constituents in Polygonatum cyrtonema Hua Using UHPLC-Q-Exactive Orbitrap Mass Spectrometry
A Systematic Method for the Identification of Oligosaccharide Constituents in Polygonatum cyrtonema Hua Using UHPLC-Q-Exactive Orbitrap Mass Spectrometry Open
A Polygonatum cyrtonema Hua (PCH) is a common medicinal and edible plant whose rhizomes are widely used for the treatment and prevention of various diseases. Previous studies have revealed a variety of chemical components such as polysacch…
View article: tRF-AspGTC Promotes Intracranial Aneurysm Formation by Controlling TRIM29-Mediated Galectin-3 Ubiquitination
tRF-AspGTC Promotes Intracranial Aneurysm Formation by Controlling TRIM29-Mediated Galectin-3 Ubiquitination Open
Transfer RNA-derived small RNAs, a recently identified class of small noncoding RNAs, play a crucial role in regulating gene expression and are implicated in cerebrovascular diseases. However, the specific biological roles and mechanisms o…
View article: A Systematic Methodology for the Identification of the Chemical Composition of the Mongolian Drug Erdun-Uril Compound Utilizing UHPLC-Q-Exactive Orbitrap Mass Spectrometry
A Systematic Methodology for the Identification of the Chemical Composition of the Mongolian Drug Erdun-Uril Compound Utilizing UHPLC-Q-Exactive Orbitrap Mass Spectrometry Open
The traditional Mongolian medicine Erdun-Uril is a conventional combination of 29 herbs commonly used for the treatment of cerebrovascular ailments. It has the effects of reducing inflammation, counteracting oxidative stress, and averting …
View article: Integrated analysis of single-cell sequencing and machine learning identifies a signature based on monocyte/macrophage hub genes to analyze the intracranial aneurysm associated immune microenvironment
Integrated analysis of single-cell sequencing and machine learning identifies a signature based on monocyte/macrophage hub genes to analyze the intracranial aneurysm associated immune microenvironment Open
Monocytes are pivotal immune cells in eliciting specific immune responses and can exert a significant impact on the progression, prognosis, and immunotherapy of intracranial aneurysms (IAs). The objective of this study was to identify mono…
View article: Preparation of porous carbon fibres : A review
Preparation of porous carbon fibres : A review Open
Porous carbon fibres(PCF) was extensively applied to energy storage, environment pollution control and healthcare due to their superior electrical conductivity, diverse aperture,high specific surface area and super electrochemical stabilit…
View article: PLP2 Could Be a Prognostic Biomarker and Potential Treatment Target in Glioblastoma Multiforme
PLP2 Could Be a Prognostic Biomarker and Potential Treatment Target in Glioblastoma Multiforme Open
PLP2's upregulation in GBM may adversely influence the lifespan of GBM patients. The involvement of PLP2 in pathways linked to leukocyte function is suggested. The positive correlation between PLP2 and PD-L1 could provide insights into PLP…
View article: Transcranial direct‐current stimulation confers neuroprotection by regulating isoleucine‐dependent signalling after rat cerebral ischemia–reperfusion injury
Transcranial direct‐current stimulation confers neuroprotection by regulating isoleucine‐dependent signalling after rat cerebral ischemia–reperfusion injury Open
Isoleucine is a branched chain amino acid. The role of isoleucine in cerebral ischemia–reperfusion injury remains unclear. Here, we show that the concentration of isoleucine is decreased in cerebrospinal fluid in a rat model of cerebral is…
View article: Preoperative systemic immune-inflammation index may predict prolonged mechanical ventilation in patients with spontaneous basal ganglia intracerebral hemorrhage undergoing surgical operation
Preoperative systemic immune-inflammation index may predict prolonged mechanical ventilation in patients with spontaneous basal ganglia intracerebral hemorrhage undergoing surgical operation Open
Background Prolonged mechanical ventilation (PMV) has been proven as a risk factor for poor prognosis in patients with neurocritical illness. Spontaneous basal ganglia intracerebral hemorrhage (ICH) is one common subtype of hemorrhagic str…
View article: EVALUATION OF THE VARIABLE GRID RESOLUTION SCHEME BASED ON COMPLEX AND SIMPLE TERRAIN SCENARIOS
EVALUATION OF THE VARIABLE GRID RESOLUTION SCHEME BASED ON COMPLEX AND SIMPLE TERRAIN SCENARIOS Open
In a nuclear accident consequence evaluation, the complex terrain is one of the key factors that affect the simulation result. Increasing the grid resolution of the dispersion model can reproduce more plume details in a scenario with compl…
View article: Iodine-125 brachytherapy treatment for newly diagnosed brain metastasis in non-small cell lung cancer: A biocentric analysis
Iodine-125 brachytherapy treatment for newly diagnosed brain metastasis in non-small cell lung cancer: A biocentric analysis Open
Purpose The aim of the present study is to evaluate the safety and efficacy of iodine-125 brachytherapy for newly diagnosed brain metastasis in patients with non-small cell lung cancer (NSCLC). Materials and methods The study included 158 …
View article: First Discovery of Cholesterol-Lowering Activity of Parthenolide as NPC1L1 Inhibitor
First Discovery of Cholesterol-Lowering Activity of Parthenolide as NPC1L1 Inhibitor Open
Elevated cholesterol significantly increases the risk of developing atherosclerosis and coronary heart disease. The key to treating hypercholesterolemia is lowering plasma cholesterol levels. There have been no studies on the cholesterol-l…
View article: Size of contralateral aneurysm: an indicator of Posterior Communicating artery mirror aneurysm management
Size of contralateral aneurysm: an indicator of Posterior Communicating artery mirror aneurysm management Open
Introduction : Intracranial mirror aneurysm is one of the subspecies of multiple intracranial aneurysms. The clear consensus on the treatment of mirror aneurysms has not come into existence. We investigated the preoperative value for radio…
View article: Post-traumatic growth trajectories among frontline healthcare workers during the COVID-19 pandemic: A three-wave follow-up study in mainland China
Post-traumatic growth trajectories among frontline healthcare workers during the COVID-19 pandemic: A three-wave follow-up study in mainland China Open
Objectives The COVID-19 pandemic has taken a significant toll on people worldwide for more than 2 years. Previous studies have highlighted the negative effects of COVID-19 on the mental health of healthcare workers (HCWs) more than the pos…
View article: Ultrasonography for Serial Monitoring and Management of Cerebrospinal Fluid Dynamic Disorders After Decompressive Craniectomy
Ultrasonography for Serial Monitoring and Management of Cerebrospinal Fluid Dynamic Disorders After Decompressive Craniectomy Open
Objective: Decompressive craniectomy (DC) is widely used to treat intracranial hypertension following severe head injury. However, impairments of cerebrospinal fluid (CSF) hydrodynamics such as hydrocephalus and subdural effusion are commo…
View article: Promoting the Development of Astragalus mongholicus Bunge Industry in Guyang County (China) Based on MaxEnt and Remote Sensing
Promoting the Development of Astragalus mongholicus Bunge Industry in Guyang County (China) Based on MaxEnt and Remote Sensing Open
To provide high-quality Astragalus mongholicus Bunge to domestic and foreign markets and maintain sustainable development of the A. mongholicus industry, Firstly, we evaluated the impact of environmental factors and planting areas on the A…
View article: Size of contralateral aneurysm: an indicator of Posterior Communicating artery mirror aneurysm management
Size of contralateral aneurysm: an indicator of Posterior Communicating artery mirror aneurysm management Open
Introduction : Intracranial mirror aneurysm is one of the subspecies of multiple intracranial aneurysms. The clear consensus on the treatment of mirror aneurysms has not come into existence. We investigated the preoperative value for radio…
View article: Risk factors for hospital-acquired and community-acquired pressure injuries: a multicentre mixed case–control study
Risk factors for hospital-acquired and community-acquired pressure injuries: a multicentre mixed case–control study Open
Objectives To separately examine and comprehensively compare the risk factors for hospital-acquired (HAPIs) and community-acquired pressure injuries (CAPIs). Design A mixed case–control study. Setting Four medical centres in China. Partici…
View article: Nicotinic Acid Riboside Regulates Nrf‐2/P62‐Related Oxidative Stress and Autophagy to Attenuate Doxorubicin‐Induced Cardiomyocyte Injury
Nicotinic Acid Riboside Regulates Nrf‐2/P62‐Related Oxidative Stress and Autophagy to Attenuate Doxorubicin‐Induced Cardiomyocyte Injury Open
Doxorubicin (Dox) is an effective chemotherapeutic drug for the treatment of various cancers. Due to its potential fatal cardiotoxic side effects, the clinical application is often limited. Dexrazoxane (Dex) is the only drug approved by th…
View article: The existence and properties of the solution of a class of nonlinear differential equations with switching at variable times
The existence and properties of the solution of a class of nonlinear differential equations with switching at variable times Open
In this paper, we deal with the qualitative theory for a class of nonlinear differential equations with switching at variable times (SSVT), such as the existence and uniqueness of the solution, the continuous dependence and differentiabili…
View article: Future development of Good Agricultural Practice in China under globalization of traditional herbal medicine trade
Future development of Good Agricultural Practice in China under globalization of traditional herbal medicine trade Open
Traditional herbal medicine (THM) is an important part of the traditional Chinese medicine culture. Due to its high medicinal potential, it should not only serve for the Chinese people's medical use, but also contribute to the world medici…
View article: Ultrasonography for Serial Monitoring and Management of CSF Dynamic Disorders After Decompressive Craniectomy
Ultrasonography for Serial Monitoring and Management of CSF Dynamic Disorders After Decompressive Craniectomy Open
Objective Decompressive craniectomy (DC) is widely used to treat intracranial hypertension following severe head injury. However, impairments of cerebrospinal fluid (CSF) hydrodynamics such as hydrocephalus and subdural effusion are common…
View article: Down-Regulation of PDCD4 Promotes Proliferation, Angiogenesis and Tumorigenesis in Glioma Cells
Down-Regulation of PDCD4 Promotes Proliferation, Angiogenesis and Tumorigenesis in Glioma Cells Open
The programmed cell death 4 (PDCD4) tumor-suppressor gene regulates cell apoptosis, protein translation, signal transduction, and induction of mediators of inflammation. However, the mechanism by which PDCD4 is down-regulated and regulates…
View article: Arginine is neuroprotective through suppressing HIF-1α/LDHA-mediated inflammatory response after cerebral ischemia/reperfusion injury
Arginine is neuroprotective through suppressing HIF-1α/LDHA-mediated inflammatory response after cerebral ischemia/reperfusion injury Open
Neuroinflammation is a secondary response following ischemia stroke. Arginine is a non-essential amino acid that has been shown to inhibit acute inflammatory reaction. In this study we show that arginine treatment decreases neuronal death …