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View article: THU269 Ethnic Differences In Hepatic Insulin Clearance: A Cross-Sectional Study Comparing South Asians And Non-Hispanic Whites
THU269 Ethnic Differences In Hepatic Insulin Clearance: A Cross-Sectional Study Comparing South Asians And Non-Hispanic Whites Open
Disclosure: A.L. Ramanathan: None. H. Fan: None. R. Muniyappa: None. Background: Hepatic insulin clearance homeostaticallyregulates peripheral plasma insulin concentration. Reduced or impaired insulinclearance promotes insulin resistance a…
View article: Acute pharmacodynamic responses to exenatide: Drug‐induced increases in insulin secretion and glucose effectiveness
Acute pharmacodynamic responses to exenatide: Drug‐induced increases in insulin secretion and glucose effectiveness Open
Aim Glucagon‐like peptide‐1 receptor agonists provide multiple benefits to patients with type 2 diabetes, including improved glycaemic control, weight loss and decreased risk of major adverse cardiovascular events. Because drug responses v…
View article: Acute pharmacodynamic responses to exenatide: Drug-induced increases in insulin secretion and glucose effectiveness
Acute pharmacodynamic responses to exenatide: Drug-induced increases in insulin secretion and glucose effectiveness Open
Background GLP1R agonists provide multiple benefits to patients with type 2 diabetes – including improved glycemic control, weight loss, and decreased risk of major adverse cardiovascular events. Because drug responses vary among individua…
View article: Minimal Model–Derived Insulin Sensitivity Index Underestimates Insulin Sensitivity in Black Americans
Minimal Model–Derived Insulin Sensitivity Index Underestimates Insulin Sensitivity in Black Americans Open
OBJECTIVE To examine the ethnic differences in insulin sensitivity (SI) as measured by the minimal model approach (SI-MM) and the reference method, the euglycemic-hyperinsulinemic clamp (EHC). RESEARCH DESIGN AND METHODS In a prospective s…