Hugo Dumargne
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View article: Subcutaneous interstitial pressure measurement during early septic shock: an exploratory study
Subcutaneous interstitial pressure measurement during early septic shock: an exploratory study Open
Fluid therapy is crucial in managing septic shock but may result in harmful fluid overload due to capillary leakage, causing interstitial fluid accumulation. Burns and endotoxemia models demonstrate that interstitium can reduce its hydrost…
View article: Volume kinetics in a translational porcine model of stabilized sepsis with fluid accumulation
Volume kinetics in a translational porcine model of stabilized sepsis with fluid accumulation Open
After sepsis, fluid was accumulated in the slow-exchange compartment, and further fluid administration distributed preferentially to the fast-exchange compartment with acceleration of lymph flow, improved plasma expansion, and recruitment …
View article: Subcutaneous interstitial pressure measurement during early septic shock: a case-control study
Subcutaneous interstitial pressure measurement during early septic shock: a case-control study Open
Background Fluid therapy is the cornerstone of septic shock management, but it is also responsible of a deleterious fluid overload, corresponding to accumulation of fluid in the interstitium due to capillary leakage. Interstitium contribut…
View article: Exploration of COVID-19 associated bradycardia using heart rate variability analysis in a case-control study of ARDS patients
Exploration of COVID-19 associated bradycardia using heart rate variability analysis in a case-control study of ARDS patients Open
This study confirmed that C-ARDS was associated with marked bradycardia and severe ANS impairment, suggesting a sympathovagal imbalance with vagal overtone. Poor outcomes appeared to be more related to sympathetic rather than parasympathet…
View article: Role of the interstitium during septic shock: a key to the understanding of fluid dynamics?
Role of the interstitium during septic shock: a key to the understanding of fluid dynamics? Open