Hui Qi Loo
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Intraspecific Diversity of <i>Staphylococcus aureus</i> Populations Isolated from Cystic Fibrosis Respiratory Infections Open
Chronic bacterial infections are often polymicrobial, comprising multiple bacterial species or variants of the same species. Because chronic infections may last for decades, they have the potential to generate high levels of intraspecific …
Species-Wide Phylogenomics of the Staphylococcus aureus <i>Agr</i> Operon Revealed Convergent Evolution of Frameshift Mutations Open
Staphylococcus aureus is a globally pervasive pathogen that produces a plethora of toxic molecules that can harm host immune cells. Production of these toxins is mainly controlled by an active agr quorum-sensing system, which senses and re…
Species-wide phylogenomics of the <i>Staphylococcus aureus agr</i> operon reveals convergent evolution of frameshift mutations Open
Staphylococcus aureus is a prominent nosocomial pathogen that causes several life-threatening diseases such as pneumonia and bacteremia. S. aureus modulates expression of its arsenal of virulence factors through sensing and integrating res…