Hui Xing Tan
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View article: Pioneering Arterial Hypertension Phenotyping on Nationally Aggregated Electronic Health Records
Pioneering Arterial Hypertension Phenotyping on Nationally Aggregated Electronic Health Records Open
Background: Hypertension is frequently studied in epidemiological studies that have been conducted using retrospective observational data, either as an outcome or a variable. However, there are few validation studies investigating the accu…
View article: An updated analysis on myocarditis and pericarditis cases reported following mRNA SARS-CoV-2 vaccination in Singapore
An updated analysis on myocarditis and pericarditis cases reported following mRNA SARS-CoV-2 vaccination in Singapore Open
Introduction: Messenger ribonucleic acid (mRNA) severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2) vaccines have been associated with myocarditis/pericarditis, especially in young males. We evaluated the risk of myocarditis/peric…
View article: A novel bidirectional LSTM deep learning approach for COVID-19 forecasting
A novel bidirectional LSTM deep learning approach for COVID-19 forecasting Open
COVID-19 has resulted in significant morbidity and mortality globally. We develop a model that uses data from thirty days before a fixed time point to forecast the daily number of new COVID-19 cases fourteen days later in the early stages …
View article: Applying the OMOP Common Data Model to Facilitate Benefit-Risk Assessments of Medicinal Products Using Real-World Data from Singapore and South Korea
Applying the OMOP Common Data Model to Facilitate Benefit-Risk Assessments of Medicinal Products Using Real-World Data from Singapore and South Korea Open
Objectives: The aim of this study was to characterize the benefits of converting Electronic Medical Records (EMRs) to a common data model (CDM) and to assess the potential of CDM-converted data to rapidly generate insights for benefit-risk…
View article: Analysis of Dual Combination Therapies Used in Treatment of Hypertension in a Multinational Cohort
Analysis of Dual Combination Therapies Used in Treatment of Hypertension in a Multinational Cohort Open
In this study, large variation in the transition between monotherapy and dual combination therapy for hypertension was observed across countries and by demographic group. These findings suggest that future research may be needed to investi…
View article: Characterizing Dual Combination Therapy Use in Treatment Escalation of Hypertension: Real-World Evidence from Multinational Cohorts
Characterizing Dual Combination Therapy Use in Treatment Escalation of Hypertension: Real-World Evidence from Multinational Cohorts Open
Background Over one billion adults have hypertension globally, of whom approximately 70% cannot achieve blood pressure control goal with monotherapy alone. Data are lacking on patterns of dual combination therapies prescribed to patients w…
View article: Transforming electronic medical records to a common data model for real-world benefit-risk assessments in a tertiary care facility in Singapore
Transforming electronic medical records to a common data model for real-world benefit-risk assessments in a tertiary care facility in Singapore Open
Aim: To assess the feasibility of converting electronic medical records (EMR) into the Observational Medical Outcomes Partnership-Common Data Model (OMOP-CDM) schema and potential for subsequent analyses relating to drug safety. Methods: T…