Huiguang Yi
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View article: MetaKSSD: Boosting the Scalability of Reference Taxonomic Marker Database and the Performance of Metagenomic Profiling Using Sketch Operations
MetaKSSD: Boosting the Scalability of Reference Taxonomic Marker Database and the Performance of Metagenomic Profiling Using Sketch Operations Open
The rapid increase in genomes and metagenomic data presents major scalability and efficiency challenges for current metagenomic profilers. In response, we introduce MetaKSSD, which redefines reference taxonomic marker database (MarkerDB) c…
View article: An integrated genetic‐epigenetic analysis shed light on the mechanisms linking coronavirus disease 2019 (COVID‐19) and cancer
An integrated genetic‐epigenetic analysis shed light on the mechanisms linking coronavirus disease 2019 (COVID‐19) and cancer Open
The Coronavirus disease 2019 (COVID-19) is an emerging disease caused by severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2) infection [1, 2]. It has spread rapidly across the world and caused a global health emergency. As of 10 F…
View article: Additional file 2 of Kssd: sequence dimensionality reduction by k-mer substring space sampling enables real-time large-scale datasets analysis
Additional file 2 of Kssd: sequence dimensionality reduction by k-mer substring space sampling enables real-time large-scale datasets analysis Open
Additional file 2: Table S1. 6164 Species Inconsistency Runs.
View article: Additional file 3 of Kssd: sequence dimensionality reduction by k-mer substring space sampling enables real-time large-scale datasets analysis
Additional file 3 of Kssd: sequence dimensionality reduction by k-mer substring space sampling enables real-time large-scale datasets analysis Open
Additional file 3: Table S2. 160 randomly selected Runs.
View article: 2019 Novel Coronavirus Is Undergoing Active Recombination
2019 Novel Coronavirus Is Undergoing Active Recombination Open
View article: Sequences Dimensionality-Reduction by <i>K</i>-mer Substring Space Sampling Enables Effective Resemblance- and Containment-Analysis for Large-Scale omics-data
Sequences Dimensionality-Reduction by <i>K</i>-mer Substring Space Sampling Enables Effective Resemblance- and Containment-Analysis for Large-Scale omics-data Open
We proposed a new sequence sketching technique named k -mer substring space decomposition (kssd), which sketches sequences via k -mer substring space sampling instead of local-sensitive hashing. Kssd is more accurate and faster for resembl…
View article: Structure-Function Analysis of the Transmembrane Protein AmpG from Pseudomonas aeruginosa
Structure-Function Analysis of the Transmembrane Protein AmpG from Pseudomonas aeruginosa Open
AmpG is a transmembrane protein with permease activity that transports meuropeptide from the periplasm to the cytoplasm, which is essential for the induction of the ampC encoding β-lactamase. To obtain new insights into the relationship be…
View article: Comparative genomics analysis of pKF3-94 in Klebsiella pneumoniae reveals plasmid compatibility and horizontal gene transfer
Comparative genomics analysis of pKF3-94 in Klebsiella pneumoniae reveals plasmid compatibility and horizontal gene transfer Open
In order to get insights into plasmid evolution and the dissemination of multidrug resistance, we performed extensive comparative genomics analyses of the Klebsiella pneumoniae plasmid pKF3-94 and some of its related plasmids. pKF3-94 is o…
View article: Molecular Epidemiology and Characterization of Genotypes of <i>Acinetobacter baumannii</i> Isolates from Regions of South China
Molecular Epidemiology and Characterization of Genotypes of <i>Acinetobacter baumannii</i> Isolates from Regions of South China Open
The aim of this study was to analyze the molecular epidemiologic characteristics of Acinetobacter baumannii. A total of 398 isolates were collected in 7 regions of South China from January to June of 2012. Drug sensitivity was tested towar…