Huiji Kim
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View article: Anti-cancer effects of wistin on malignant melanoma cells
Anti-cancer effects of wistin on malignant melanoma cells Open
Malignant melanoma (MM) is a severe skin cancer that arises from melanocytes, primarily caused by exposure to ultraviolet radiation. Although MM occurs less frequently than other skin cancers, its metastasis is easily activated, leading to…
View article: 3-bromo-4-(2-hydroxyethyl)-7-methoxy-2H-chromen-2-one inhibits allergic reactions in IgE-mediated RBL-2H3 cells and a passive cutaneous anaphylaxis mouse model
3-bromo-4-(2-hydroxyethyl)-7-methoxy-2H-chromen-2-one inhibits allergic reactions in IgE-mediated RBL-2H3 cells and a passive cutaneous anaphylaxis mouse model Open
Allergic reactions occur when the immune system overreacts to generally harmless substances, leading to both acute and chronic diseases, which can be fatal. Mast cells are critical mediators of allergic reactions as they bind allergens and…
View article: Anti-inflammatory effects of TP1 in LPS-induced Raw264.7 macrophages
Anti-inflammatory effects of TP1 in LPS-induced Raw264.7 macrophages Open
Inflammation is an essential defense mechanism in health; however, excessive inflammation contributes to the pathophysiology of several chronic diseases. Although anti-inflammatory drugs are essential for controlling inflammation, they hav…
View article: DB3 from Antarctic lichen inhibits the growth of B16F10 melanoma cells in vitro and in vivo
DB3 from Antarctic lichen inhibits the growth of B16F10 melanoma cells in vitro and in vivo Open
Malignant melanoma is a fatal disease with an increasing global incidence. Despite numerous studies focused on anti-cancer drugs, a variety of side effects of cancer treatment remain challenging. Thus, there is a pressing need to identify …
View article: Afrormosin exerts an anticancer effect via MAPK and AKT signaling pathways in B16F10 cells
Afrormosin exerts an anticancer effect via MAPK and AKT signaling pathways in B16F10 cells Open
Melanoma is a deadly skin cancer with high mortality, and its incidence is increasing every year. Although numerous anticancer drugs have been developed, these treatments have various side effects, such as skin rash, fatigue, diarrhea, cou…
View article: Wistin Exerts an Anti-Inflammatory Effect via Nuclear Factor-κB and p38 Signaling Pathways in Lipopolysaccharide-Stimulated RAW264.7 Cells
Wistin Exerts an Anti-Inflammatory Effect via Nuclear Factor-κB and p38 Signaling Pathways in Lipopolysaccharide-Stimulated RAW264.7 Cells Open
Inflammation is an immune response to cellular damage caused by various stimuli (internal or external) and is essential to human health. However, excessive inflammatory responses may be detrimental to the host. Considering that the existin…
View article: Anti-cancer effects of lucidadiol against malignant melanoma cells
Anti-cancer effects of lucidadiol against malignant melanoma cells Open
Melanoma is one of the most aggressive and lethal skin cancers. Lucidadiol is a triterpenoid isolated from Ganoderma lucidum and is known to have various biological functions, including antibacterial effects. However, the anti-cancer effec…
View article: Physiological Roles of Apoptotic Cell Clearance: Beyond Immune Functions
Physiological Roles of Apoptotic Cell Clearance: Beyond Immune Functions Open
The clearance of apoptotic cells is known to be a critical step in maintaining tissue and organism homeostasis. This process is rapidly/promptly mediated by recruited or resident phagocytes. Phagocytes that engulf apoptotic cells have been…