Huiling Deng
YOU?
Author Swipe
View article: Steered by digitization and incentives: The configuration and effect of improving innovation efficiency in manufacturing companies
Steered by digitization and incentives: The configuration and effect of improving innovation efficiency in manufacturing companies Open
View article: Atomistic mechanisms of phase transitions in all-temperature barocaloric material KPF6
Atomistic mechanisms of phase transitions in all-temperature barocaloric material KPF6 Open
View article: Polysaccharides from Rosa roxburghii Tratt fruit: The effect of extraction solvent on their chemical structure, bioactivities, in vitro simulated digestion and fecal fermentation characteristics
Polysaccharides from Rosa roxburghii Tratt fruit: The effect of extraction solvent on their chemical structure, bioactivities, in vitro simulated digestion and fecal fermentation characteristics Open
View article: COVID-19 pandemic increased ESKAPEEc bloodstream infections and amplified carbapenem resistance in Chinese children: a multicenter surveillance study (2016–2023)
COVID-19 pandemic increased ESKAPEEc bloodstream infections and amplified carbapenem resistance in Chinese children: a multicenter surveillance study (2016–2023) Open
Objective This study investigated the long-term trends in the distribution and antibiograms of ESKAPEEc pathogens in neonatal and pediatric bloodstream infections (BSIs), shifts in minimum inhibitory concentration (MIC) of vancomycin and l…
View article: Integrative scRNA-seq and transcriptomic analysis initially reveals monocyte/macrophage activation drives EV-A71-induced immune dysregulation and neural injury in severe HFMD
Integrative scRNA-seq and transcriptomic analysis initially reveals monocyte/macrophage activation drives EV-A71-induced immune dysregulation and neural injury in severe HFMD Open
Objective Enterovirus 71 (EV-A71) is a major pathogen of severe hand, foot and mouth disease (HFMD) in children, but the mechanism by which it develops into severe HFMD remains unclear, especially the role of macrophage-mediated immune dys…
View article: Restoration of antibiotic associated diarrhea induced gut microbiota disorder by using Dictyophora indusiata water-insoluble polysaccharides in C57BL/6J mice
Restoration of antibiotic associated diarrhea induced gut microbiota disorder by using Dictyophora indusiata water-insoluble polysaccharides in C57BL/6J mice Open
Background A healthy gut depends on a balance of commensal and probiotic bacteria, and prolonged and inappropriate clinical use of antibiotics can cause an imbalance in the gut flora, resulting in antibiotic-associated diarrhea (AAD). Macr…
View article: Plasma nontargeted metabolomics study of H1N1 and H3N2 influenza in children
Plasma nontargeted metabolomics study of H1N1 and H3N2 influenza in children Open
Background This study used a nontargeted metabolomic approach to investigate small molecular metabolites in the peripheral blood of pediatric patients with influenza. By comparing these metabolites with those in healthy children, potential…
View article: Bacterial Epidemiology and Antimicrobial Resistance Profiles of Bloodstream Infections Caused by Negative Bacteria in Children’s: A Multicenter Study in China (2016–2022)
Bacterial Epidemiology and Antimicrobial Resistance Profiles of Bloodstream Infections Caused by Negative Bacteria in Children’s: A Multicenter Study in China (2016–2022) Open
The detection rate of gram-negative pathogens showed an increasing trend among the bloodstream infection. The detection rate of CRKPN assumed a downward trend in 2018. There are differences types of pathogens between the neonatal group and…
View article: Invasive pneumococcal diseases in Chinese children: a multicentre hospital-based active surveillance from 2019 to 2021
Invasive pneumococcal diseases in Chinese children: a multicentre hospital-based active surveillance from 2019 to 2021 Open
This study aimed to provide data for the clinical features of invasive pneumococcal disease (IPD) and the molecular characteristics of Streptococcus pneumoniae isolates from paediatric patients in China. We conducted a multi-centre …
View article: Expression and clinical significance of pattern recognition receptor-associated genes in hand, foot and mouth disease
Expression and clinical significance of pattern recognition receptor-associated genes in hand, foot and mouth disease Open
Objective: To explore which pattern recognition receptors (PRRs) play a key role in the development of hand, foot, and mouth disease (HFMD) by analyzing PRR-associated genes. Methods: We conducted a comparative analysis of PRR-associated g…
View article: [A multi-center epidemiological study on pneumococcal meningitis in children from 2019 to 2020].
[A multi-center epidemiological study on pneumococcal meningitis in children from 2019 to 2020]. Open
Pediatric PM is more common in children aged 3 months to under 3 years. Intracranial complications are more frequently observed in children under 1 year old. Fever is the most common clinical manifestation of PM, and subdural effusion/emph…
View article: Water-Insoluble Polysaccharide Extracted from Poria cocos Alleviates Antibiotic-Associated Diarrhea Based on Regulating the Gut Microbiota in Mice
Water-Insoluble Polysaccharide Extracted from Poria cocos Alleviates Antibiotic-Associated Diarrhea Based on Regulating the Gut Microbiota in Mice Open
Antibiotics are very effective in treating a variety of bacterial infections, while clinical overuse of antibiotics can lead to diseases such as antibiotic-associated diarrhea. Numerous studies have shown that natural polysaccharides can b…
View article: Clinical characteristics and antibiotic resistance profile of invasive MRSA infections in newborn inpatients: a retrospective multicenter study from China
Clinical characteristics and antibiotic resistance profile of invasive MRSA infections in newborn inpatients: a retrospective multicenter study from China Open
View article: Antimicrobial resistance profile of methicillin-resistant Staphylococcus aureus isolates in children reported from the ISPED surveillance of bacterial resistance, 2016–2021
Antimicrobial resistance profile of methicillin-resistant Staphylococcus aureus isolates in children reported from the ISPED surveillance of bacterial resistance, 2016–2021 Open
Introduction Methicillin-resistant Staphylococcus aureus (MRSA) poses a serious threat to public health worldwide. In December 2015, the Infectious Disease Surveillance of Pediatrics (ISPED) program was organized to monitor bacterial epide…
View article: Metabolomics in the Research of Viral Infectious Disease Mechanisms
Metabolomics in the Research of Viral Infectious Disease Mechanisms Open
Viral invasion of the body causes metabolic changes involving pathways such as gluconeogenesis, amino acid metabolism, lipid metabolism, the TCA cycle, and energy metabolism and affects vital bodily processes such as nucleic acid, protein,…
View article: Construction of Cytosine-Rich Ssdna for Ultralow Detection of Salmonella Typhimurium by Enhancing the Peroxidase-Like Activity of Fe3o4@Au Nanoparticles
Construction of Cytosine-Rich Ssdna for Ultralow Detection of Salmonella Typhimurium by Enhancing the Peroxidase-Like Activity of Fe3o4@Au Nanoparticles Open
View article: Additional file 1 of Clinical characteristics and antibiotic resistance profile of invasive MRSA infections in newborn inpatients: a retrospective multicenter study from China
Additional file 1 of Clinical characteristics and antibiotic resistance profile of invasive MRSA infections in newborn inpatients: a retrospective multicenter study from China Open
Supplementary Material 1
View article: Mechanistic Investigation and Dual-Mode Colorimetric-Chemiluminescent Detection of Glyphosate Based on the Specific Inhibition of Fe3o4@Cu Nanozyme Peroxidase-Like Activity
Mechanistic Investigation and Dual-Mode Colorimetric-Chemiluminescent Detection of Glyphosate Based on the Specific Inhibition of Fe3o4@Cu Nanozyme Peroxidase-Like Activity Open
View article: Three main metabolites from Wolfiporia cocos (F. A. Wolf) Ryvarden & Gilb regulate the gut microbiota in mice: A comparative study using microbiome-metabolomics
Three main metabolites from Wolfiporia cocos (F. A. Wolf) Ryvarden & Gilb regulate the gut microbiota in mice: A comparative study using microbiome-metabolomics Open
Wolfiporia cocos (F. A. Wolf) Ryvarden & Gilb, also known as Poria cocos is an ancient edible and medicinal mushroom that has been valued for thousands of years for its tranquilizing, diuretic, and spleen-enhancing properties. Because …
View article: The Damage of the Crayfish (Procambarus Clarkii) Digestive Organs Caused by Citrobacter Freundii Is Associated With the Disturbance of Intestinal Microbiota and Disruption of Intestinal-Liver Axis Homeostasis
The Damage of the Crayfish (Procambarus Clarkii) Digestive Organs Caused by Citrobacter Freundii Is Associated With the Disturbance of Intestinal Microbiota and Disruption of Intestinal-Liver Axis Homeostasis Open
As a common conditional pathogenic bacterium in nature, C. freundii has posed a threat to crayfish culture and may infect humans through consumption. However, the pathogenic mechanism of C. freundii in crayfish remains unknown, which poses…
View article: Antibiotics prescription for targeted therapy of pediatric invasive pneumococcal diseases in China: a multicenter retrospective study
Antibiotics prescription for targeted therapy of pediatric invasive pneumococcal diseases in China: a multicenter retrospective study Open
View article: Antimicrobial resistance of Haemophilus influenzae isolates from pediatric hospitals in Mainland China: Report from the ISPED program, 2017–2019
Antimicrobial resistance of Haemophilus influenzae isolates from pediatric hospitals in Mainland China: Report from the ISPED program, 2017–2019 Open
There is a rising trend of resistance rate of ampicillin and azithromycin in H. influenzae. Antimicrobial resistance of H. influenzae deserves our ongoing attention. Third-generation cephalosporin could be the preferred treatment option of…
View article: Clinical characteristics and effectiveness of antiviral agents in hospitalized children with infectious mononucleosis in China: A multicenter retrospective study
Clinical characteristics and effectiveness of antiviral agents in hospitalized children with infectious mononucleosis in China: A multicenter retrospective study Open
Importance The clinical characteristics of infectious mononucleosis (IM) in Chinese children have not been evaluated in multicenter studies, and the effectiveness of antiviral treatment are controversial. Objective To investigate the clini…
View article: Transient infantile hypertriglyceridemia with jaundice
Transient infantile hypertriglyceridemia with jaundice Open
Rationale: Transient infantile hypertriglyceridemia (HTGTI) is a rare autosomal recessive inherited disease caused by inactivating mutations in the glycerol-3-phosphate dehydrogenase 1 gene. To date, only a few patients have been reported …
View article: Antibiotics prescription for targeted therapy of pediatric invasive pneumococcal diseases in China: a multicenter retrospective study
Antibiotics prescription for targeted therapy of pediatric invasive pneumococcal diseases in China: a multicenter retrospective study Open
Background: Streptococcus pneumoniae ( S. pneumoniae ) is a major cause of bacterial meningitis, septicemia and pneumonia in children. Inappropriate choice of antibiotic can have important adverse consequences for both the individual and t…
View article: DNA methylation and SNP in IFITM3 are correlated with hand, foot and mouth disease caused by enterovirus 71
DNA methylation and SNP in IFITM3 are correlated with hand, foot and mouth disease caused by enterovirus 71 Open
IFITM3 methylation status and SNP genotyping may help clinicians to choose the correct treatment strategy for patients with EV71-HFMD.
View article: Response to: Comment on “Antibiotic Resistance Profiles of Haemophilus influenzae Isolates from Children in 2016: A Multicenter Study in China”
Response to: Comment on “Antibiotic Resistance Profiles of Haemophilus influenzae Isolates from Children in 2016: A Multicenter Study in China” Open
View article: <p>Prognostic Value of Neutrophil-to-Lymphocyte Ratio in Predicting Death Risk in Patients with Severe Hand, Foot and Mouth Disease</p>
Prognostic Value of Neutrophil-to-Lymphocyte Ratio in Predicting Death Risk in Patients with Severe Hand, Foot and Mouth Disease Open
In conclusion, NLR (>2.01) in severe HFMD and NLR (>2.50) in critical HFMD patients may be associated with increased death risk.
View article: Antibiotic Resistance Profiles of <i>Haemophilus influenzae</i> Isolates from Children in 2016: A Multicenter Study in China
Antibiotic Resistance Profiles of <i>Haemophilus influenzae</i> Isolates from Children in 2016: A Multicenter Study in China Open
Background and Objective . Haemophilus influenzae (HI) is a common cause of community-acquired pneumonia in children. In many countries, HI strains are increasingly resistant to ampicillin and other commonly prescribed antibiotics, posing …
View article: [Clinical characteristics and drug sensitivity in children with invasive pneumococcal disease: a multicenter study].
[Clinical characteristics and drug sensitivity in children with invasive pneumococcal disease: a multicenter study]. Open
IPD is more common in children under 5 years old, especially in those under 2 years old. Some children with IPD have underlying diseases, and most of the patients have various risk factors for drug resistance. Pneumonia with sepsis is the …