Huiling Huang
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View article: Jasmonates regulate light-induced patchoulol biosynthesis in <i>Pogostemon cablin</i>
Jasmonates regulate light-induced patchoulol biosynthesis in <i>Pogostemon cablin</i> Open
View article: Association between obstructive sleep apnea syndrome and type1/type2 diabetes mellitus: A systematic review and meta‐analysis
Association between obstructive sleep apnea syndrome and type1/type2 diabetes mellitus: A systematic review and meta‐analysis Open
Introduction Obstructive sleep apnea (OSA) is characterized by a complete or partial obstruction of the upper airway, along with hypoxemia, microarousals, and sleep fragmentation. Compelling evidence has clarified a bidirectional correlati…
View article: Symptomatic complete heart block: A rare complication of anterior myocardial infarction in a young, fit male: A case report
Symptomatic complete heart block: A rare complication of anterior myocardial infarction in a young, fit male: A case report Open
Background: Acute myocardial infarction (AMI) is a major cause of morbidity and mortality, typically affecting older individuals with multiple cardiovascular comorbidities. Complete heart block (CHB) is a rare but serious complication of A…
View article: Scattering imaging of moving targets based on recurrent neural networks: a fusion of temporal and phase information
Scattering imaging of moving targets based on recurrent neural networks: a fusion of temporal and phase information Open
The speckle degradation caused by scattering media posed barriers to capturing the displacement information of moving objects. Moreover, the optical memory effect (OME) further restricts the imaging range, and current methodologies neglect…
View article: Burden and Temporal Trends of Valvular Heart Disease‐Related Heart Failure From 1990 to 2019 and Projection Up to 2030 in Group of 20 Countries: An Analysis for the Global Burden of Disease Study 2019
Burden and Temporal Trends of Valvular Heart Disease‐Related Heart Failure From 1990 to 2019 and Projection Up to 2030 in Group of 20 Countries: An Analysis for the Global Burden of Disease Study 2019 Open
Background The aim of this study was to characterize the burden of valvular heart disease (VHD)‐related heart failure (HF) in Group of 20 (G20) countries. Methods and Results Using data from the 2019 Global Burden of Disease Study, we esti…
View article: Three-dimensional polarimetric ptychography
Three-dimensional polarimetric ptychography Open
A three-dimensional polarimetric ptychography (3D-PP) technique is proposed to reconstruct the residual stress distribution in optical elements in three dimensions by combining polarization imaging and a 3D ptychographic iterative engine (…
View article: Age-dependent genes in adipose stem and precursor cells affect regulation of fat cell differentiation and link aging to obesity via cellular and genetic interactions
Age-dependent genes in adipose stem and precursor cells affect regulation of fat cell differentiation and link aging to obesity via cellular and genetic interactions Open
Background Age and obesity are dominant risk factors for several common cardiometabolic disorders, and both are known to impair adipose tissue function. However, the underlying cellular and genetic factors linking aging and obesity on adip…
View article: Application of Marxist-Based Science and Technology Theory in the Ethical Review of Artificial Intelligence Robots
Application of Marxist-Based Science and Technology Theory in the Ethical Review of Artificial Intelligence Robots Open
Marxist scholars' research on science and technology spans multiple levels of business, politics, and society. At the economic level, Marxist scholars recognize the contribution of science and technology to economic development. At the pol…
View article: Contactin‐6‐deficient male mice exhibit the abnormal function of the accessory olfactory system and impaired reproductive behavior
Contactin‐6‐deficient male mice exhibit the abnormal function of the accessory olfactory system and impaired reproductive behavior Open
Introduction Contactin‐6 (CNTN6), also known as NB‐3, is a neural recognition molecule and a member of the contactin subgroup of the immunoglobulin superfamily. Gene encoding CNTN6 is expressed in many regions of the neural system, includi…
View article: Deubiquitylase OTUD1 confers Erlotinib sensitivity in non-small cell lung cancer through inhibition of nuclear translocation of YAP1
Deubiquitylase OTUD1 confers Erlotinib sensitivity in non-small cell lung cancer through inhibition of nuclear translocation of YAP1 Open
View article: Cardiac function and exercise capacity in patients with metabolic syndrome: A cross-sectional study
Cardiac function and exercise capacity in patients with metabolic syndrome: A cross-sectional study Open
Background Metabolic syndrome is a pre-diabetes condition that is associated with increased cardiovascular morbidity and mortality. We aimed to explore how exercise capacity, cardiac structure, and function were affected in patients with m…
View article: Coexpression Analysis Identified PcMYB25 as a Patchoulol Synthase Gene Activator to Enhance Patchouli Alcohol Biosynthesis in Pogostemon Cablin
Coexpression Analysis Identified PcMYB25 as a Patchoulol Synthase Gene Activator to Enhance Patchouli Alcohol Biosynthesis in Pogostemon Cablin Open
BackgroundPatchouli alcohol is an effective component of the medicinal plant patchouli. Similar to other secondary metabolites, its synthesis is likely also regulated by transcription factors. Although the biosynthetic pathway of patchouli…
View article: Notoginsenoside R1 Protects Against High Glucose-Induced Cell Injury Through AMPK/Nrf2 and Downstream HO-1 Signaling
Notoginsenoside R1 Protects Against High Glucose-Induced Cell Injury Through AMPK/Nrf2 and Downstream HO-1 Signaling Open
Notoginsenoside R1 (NGR1), the primary bioactive compound found in Panax notoginseng, is believed to have antihypertrophic and antiapoptotic properties, and has long been used to prevent and treat cardiovascular diseases. However, its pote…
View article: The Role of 6-Minute Walk Test Guided by Impedance Cardiography in the Rehabilitation Following Knee Arthroplasty: A Randomized Controlled Trial
The Role of 6-Minute Walk Test Guided by Impedance Cardiography in the Rehabilitation Following Knee Arthroplasty: A Randomized Controlled Trial Open
Objective: To explore the effect of the 6-minute walk test (6MWT) guided by non-invasive cardiac output on the rehabilitation of patients with knee osteoarthritis following artificial total knee arthroplasty. Methods: About 66 patients wit…
View article: 430 A phase 1b/II clinical study of AK112, a PD-1/VEGF bispecific antibody, in combination with olaparib in BRCA germline wild-type platinum sensitive recurrent ovarian cancer
430 A phase 1b/II clinical study of AK112, a PD-1/VEGF bispecific antibody, in combination with olaparib in BRCA germline wild-type platinum sensitive recurrent ovarian cancer Open
Background Ovarian cancer is the most lethal gynecologic malignancy. Most patients will experience disease recurrence after initial platinum-based chemotherapy. Although PRAP inhibitors showed clinical benefit in terms of progression free …
View article: Acute Hemiballismus as the Initial Manifestation of Ischemic Stroke: A Case Report
Acute Hemiballismus as the Initial Manifestation of Ischemic Stroke: A Case Report Open
Introduction: Cerebrovascular disease often presents with “negative” symptoms such as weakness with reduced movement of body parts or sensory loss. Rarely do “positive” symptoms such as abnormal movements manifest in acute stroke, with hem…
View article: An electrographic AV optimization for the maximum integrative atrioventricular and ventricular resynchronization in CRT
An electrographic AV optimization for the maximum integrative atrioventricular and ventricular resynchronization in CRT Open
Background Atrioventricular (AV) delay could affect AV and ventricular synchrony in cardiac resynchronization therapy (CRT). Strategies to optimize AV delay according to optimal AV synchrony (AV opt-AV ) or ventricular synchrony (AV opt-V …
View article: Assessment of Myocardial Dysfunction by Three-Dimensional Echocardiography Combined With Myocardial Contrast Echocardiography in Type 2 Diabetes Mellitus
Assessment of Myocardial Dysfunction by Three-Dimensional Echocardiography Combined With Myocardial Contrast Echocardiography in Type 2 Diabetes Mellitus Open
Background: We aimed to explore the value of combining real-time three-dimensional echocardiography (RT-3DE) and myocardial contrast echocardiography (MCE) in the left ventricle (LV) evaluating myocardial dysfunction in type 2 diabetes mel…
View article: Clinical and Genetic Analysis of <i>KATP</i> Variants With Heart Failure Risk in Patients With Decreased Serum ApoA-I Levels
Clinical and Genetic Analysis of <i>KATP</i> Variants With Heart Failure Risk in Patients With Decreased Serum ApoA-I Levels Open
Context Lower serum concentration of apolipoprotein A-I (ApoA-I) is causally associated with heart failure (HF) risk. Adenosine triphosphate–sensitive potassium channels (KATP), as gating channels coupling vascular reactivity and metabolis…
View article: An electrographic AV optimization for the maximum integrative atrioventricular and ventricular resynchronization in CRT
An electrographic AV optimization for the maximum integrative atrioventricular and ventricular resynchronization in CRT Open
Background:Atrioventricular (AV) delay could affect AV and ventricular synchrony in cardiac resynchronization therapy (CRT). Strategies to optimize AV delay according to optimal AV synchrony (AV opt-AV ) or ventricular synchrony (AV opt-V …
View article: Coexpression Analysis Identified PcMYB25 as a Patchoulol Synthase Gene Activator to Enhance Patchouli Alcohol Biosynthesis in Pogostemon Cablin
Coexpression Analysis Identified PcMYB25 as a Patchoulol Synthase Gene Activator to Enhance Patchouli Alcohol Biosynthesis in Pogostemon Cablin Open
Background Patchouli alcohol is an effective component of the medicinal plant patchouli. Similar to other secondary metabolites, its synthesis is also regulated by transcription factors. Although the biosynthetic pathway of patchouli alcoh…
View article: Increased photosystem II translation efficiency as an important photoprotective mechanism in an Arabidopsis thaliana ecotype (Tibet-0) adapted to high light environments
Increased photosystem II translation efficiency as an important photoprotective mechanism in an Arabidopsis thaliana ecotype (Tibet-0) adapted to high light environments Open
The Qinghai-Tibet Plateau (QTP) is the highest and largest young plateau in the world, with a wide variety of extreme environments. Due to the low density of air and high transparency of the atmosphere, QTP has abundant sunshine and high l…
View article: Rapid detection of SARS-CoV-2 with CRISPR-Cas12a
Rapid detection of SARS-CoV-2 with CRISPR-Cas12a Open
The recent outbreak of betacoronavirus Severe Acute Respiratory Syndrome Coronavirus 2 (SARS-CoV-2), which is responsible for the Coronavirus Disease 2019 (COVID-19) global pandemic, has created great challenges in viral diagnosis. The exi…
View article: Pt Nanoclusters Anchored on Hollow Ag-Au Nanostructures for Electrochemical Oxidation of Methanol
Pt Nanoclusters Anchored on Hollow Ag-Au Nanostructures for Electrochemical Oxidation of Methanol Open
The synthetic method of Pt nanocluster-anchored hollow Ag-Au nanostructures and measurements of their electrocatalytic properties for methanol oxidation reaction (MOR) are reported here. In this synthesis, uniform Ag nanospheres were prepa…
View article: Cardiac hemodynamic response to the 6-minute walk test in patients with intestinal carcinoma undergoing bevacizumab treatment
Cardiac hemodynamic response to the 6-minute walk test in patients with intestinal carcinoma undergoing bevacizumab treatment Open
Estimation of hemodynamic response to 6MWT is feasible, and may provide useful information of myocardial damage in BEV-treated patients.
View article: Clinical implication of pulmonary hospitalization in heart failure with preserved ejection fraction: from the TOPCAT
Clinical implication of pulmonary hospitalization in heart failure with preserved ejection fraction: from the TOPCAT Open
Aims The aim of the study was to explore the risk factors and evaluate the prognostic implication of pulmonary hospitalization on heart failure (HF) with preserved ejection fraction (HFpEF). Methods and results We performed a secondary ana…
View article: Characteristics of COVID-2019 in areas epidemic from imported cases
Characteristics of COVID-2019 in areas epidemic from imported cases Open
View article: PatSWC4, a methyl jasmonate-responsive MYB (v-myb avian myeloblastosis viral oncogene homolog)-related transcription factor, positively regulates patchoulol biosynthesis in Pogostemon cablin
PatSWC4, a methyl jasmonate-responsive MYB (v-myb avian myeloblastosis viral oncogene homolog)-related transcription factor, positively regulates patchoulol biosynthesis in Pogostemon cablin Open
Patchoulol, the major active ingredient in Pogostemon cablin (Blanco) Benth., has considerable clinical and industrial value. A number of genes that participate in the patchoulol biosynthesis pathway have been identified; however, little i…
View article: Association between retinal arterial narrowing and left ventricular diastolic dysfunction in masked hypertensives
Association between retinal arterial narrowing and left ventricular diastolic dysfunction in masked hypertensives Open
Morphological change in retinal vessel diameters has been reported to be associated with negative cardiovascular outcomes, but its association with left ventricular diastolic dysfunction (LVDD) is not clear. This study aimed to examine the…
View article: Blood pressure control in hypertensive patients and its relation with exercise and exercise-related behaviors
Blood pressure control in hypertensive patients and its relation with exercise and exercise-related behaviors Open
The effects of exercise interventions on blood pressure control in hypertensive patients have received extensive attention and recognition. However, the influence of exercise-related behaviors on the effects of blood pressure control and t…