Hongyu Shen
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View article: Malignancy prediction for calcified thyroid nodules using deep learning based on ultrasound dynamic videos
Malignancy prediction for calcified thyroid nodules using deep learning based on ultrasound dynamic videos Open
Objective The presence of calcification, especially microcalcification, is often associated with an increased risk of malignancy and closely linked to papillary thyroid carcinoma (PTC), the most common type of thyroid cancer. However, exis…
View article: Anesthetic Cooperation and Emergency Nursing Care for Awake Intubation in a Patient with Giant Goiter Complicated by Difficult Airway
Anesthetic Cooperation and Emergency Nursing Care for Awake Intubation in a Patient with Giant Goiter Complicated by Difficult Airway Open
Objective: This study aims to explore optimized anesthetic nursing strategies for awake intubation in patients with giant goiter complicated by difficult airway, and to establish a standardized nursing process based on evidence-based guide…
View article: Author Correction: Lnc-mg is a long non-coding RNA that promotes myogenesis
Author Correction: Lnc-mg is a long non-coding RNA that promotes myogenesis Open
View article: An Interpretable Radiomics Model Integrating Ultrasound and Clinical Features for Multiclass Classification of Axillary Lymph Nodes
An Interpretable Radiomics Model Integrating Ultrasound and Clinical Features for Multiclass Classification of Axillary Lymph Nodes Open
View article: Trustworthy detection of exencephaly in high-throughput micro-CT embryo screens with focal-loss transformers
Trustworthy detection of exencephaly in high-throughput micro-CT embryo screens with focal-loss transformers Open
1. Abstract Lethal and sub-viable knockout mouse lines require whole-embryo 3D imaging to connect genotype to phenotype (Dickinson et al., 2016; Cacheiro et al., 2022). There are often far fewer samples of in-class (e.g., homozygous knocko…
View article: The plasma lipopolysaccharide level is associated with contrast-induced acute kidney injury in patients with ST-segment elevation myocardial infarction
The plasma lipopolysaccharide level is associated with contrast-induced acute kidney injury in patients with ST-segment elevation myocardial infarction Open
View article: Boosting Test Performance with Importance Sampling--a Subpopulation Perspective
Boosting Test Performance with Importance Sampling--a Subpopulation Perspective Open
Despite empirical risk minimization (ERM) is widely applied in the machine learning community, its performance is limited on data with spurious correlation or subpopulation that is introduced by hidden attributes. Existing literature propo…
View article: Multidimensional flavor analysis of Yongchun aged vinegar: Impact of aging on quality and flavor profile
Multidimensional flavor analysis of Yongchun aged vinegar: Impact of aging on quality and flavor profile Open
•Multidimensional techniques reveal the comprehensive flavor profile of aged vinegar.•Key flavor-active compounds in Yongchun Aged Vinegar were identified.•Aging enhances vinegar freshness and sweetness, boosting consumer acceptability.•To…
View article: Comparative prognosis of liver transplantation versus liver resection in intrahepatic cholangiocarcinoma: a systematic review and meta-analysis
Comparative prognosis of liver transplantation versus liver resection in intrahepatic cholangiocarcinoma: a systematic review and meta-analysis Open
For patients with ICC, LT seems to have optimistic survival results under certain conditions compared with curative hepatectomy. Since LT is a potential treatment for ICC, it is currently uncertain whether LT should be more considered in p…
View article: Wide-Band White Light Emission of Cawo4:Eu3+/ G-C3n4 Composite Phosphor Under Near Ultraviolet Excitation
Wide-Band White Light Emission of Cawo4:Eu3+/ G-C3n4 Composite Phosphor Under Near Ultraviolet Excitation Open
View article: Study on the Optical Properties of G-C3n4 Prepared by Different Precursors
Study on the Optical Properties of G-C3n4 Prepared by Different Precursors Open
View article: Boosting Test Performance with Importance Sampling--a Subpopulation Perspective
Boosting Test Performance with Importance Sampling--a Subpopulation Perspective Open
Despite empirical risk minimization (ERM) is widely applied in the machine learning community, its performance is limited on data with spurious correlation or subpopulation that is introduced by hidden attributes. Existing literature propo…
View article: MTF2 facilitates the advancement of osteosarcoma through mediating EZH2/SFRP1/Wnt signaling
MTF2 facilitates the advancement of osteosarcoma through mediating EZH2/SFRP1/Wnt signaling Open
View article: Exosomal circRHCG promotes breast cancer metastasis via facilitating M2 polarization through TFEB ubiquitination and degradation
Exosomal circRHCG promotes breast cancer metastasis via facilitating M2 polarization through TFEB ubiquitination and degradation Open
Triple-negative breast cancer (TNBC) is a highly aggressive cancer with distant metastasis. Accumulated evidence has demonstrated that exosomes are involved in TNBC metastasis. Elucidating the mechanism underlying TNBC metastasis has impor…
View article: Study on the Optical Properties of G-C3n4 Prepared by Different Precursors
Study on the Optical Properties of G-C3n4 Prepared by Different Precursors Open
View article: Multidimensional Flavor Analysis of Yongchun Aged Vinegar: Impact of Aging on Quality and Flavor Profile
Multidimensional Flavor Analysis of Yongchun Aged Vinegar: Impact of Aging on Quality and Flavor Profile Open
View article: Transcriptional repression of beige fat innervation via a YAP/TAZ-S100B axis
Transcriptional repression of beige fat innervation via a YAP/TAZ-S100B axis Open
View article: Integration of bioinformatics and machine learning strategies identifies APM-related gene signatures to predict clinical outcomes and therapeutic responses for breast cancer patients
Integration of bioinformatics and machine learning strategies identifies APM-related gene signatures to predict clinical outcomes and therapeutic responses for breast cancer patients Open
The APM-related gene signatures established in our study could improve the personalized assessment of survival risk and guide ICB decision-making for BRCA patients.
View article: GATA3 mediates doxorubicin resistance by inhibiting CYB5R2-catalyzed iron reduction in breast cancer cells
GATA3 mediates doxorubicin resistance by inhibiting CYB5R2-catalyzed iron reduction in breast cancer cells Open
GATA3 promotes doxorubicin resistance by inhibiting CYB5R2-mediated iron metabolism and ferroptosis. Therefore, patients with breast cancer who display high GATA3 expression do not benefit from doxorubicin-based NAC regimens.
View article: Construction of an m6A-related lncRNA model for predicting prognosis and immunotherapy in patients with lung adenocarcinoma
Construction of an m6A-related lncRNA model for predicting prognosis and immunotherapy in patients with lung adenocarcinoma Open
N6-methyladenosine (m6A)-related lncRNAs could be involved in the development of multiple tumors with an unknown role in lung adenocarcinoma (LUAD). Hence, gene expression data and clinical data of LUAD patients were acquired from The Canc…
View article: Integrative analysis of the role of BOLA2B in human pan-cancer
Integrative analysis of the role of BOLA2B in human pan-cancer Open
Objective: BOLA2B is a recently discovered protein-coding gene. Here, pan-cancer analysis was conducted to determine the expression patterns of BOLA2B and its impact on immune response, gene mutation, and possible molecular biological mech…
View article: Engineering c-Met-CAR NK-92 cells as a promising therapeutic candidate for lung adenocarcinoma
Engineering c-Met-CAR NK-92 cells as a promising therapeutic candidate for lung adenocarcinoma Open
Mesenchymal-epithelial transition factor (C-Met) has been acknowledged as a significant therapeutic target for treating lung adenocarcinoma (LUAD). However, the potential application of chimeric antigen receptors (CAR)-modified natural kil…
View article: Integration of bioinformatics and machine learning strategies identifies APM-related gene signatures to predict clinical outcomes and therapeutic responses for breast cancer patients
Integration of bioinformatics and machine learning strategies identifies APM-related gene signatures to predict clinical outcomes and therapeutic responses for breast cancer patients Open
Background: Tumor antigenicity and efficiency of antigen presentation jointly influence tumor immunogenicity, which largely determines the effectiveness of immune checkpoint blockade (ICB). However, the role of altered antigen processing a…
View article: PUS1 is a novel biomarker for predicting poor outcomes and triple-negative status in breast cancer
PUS1 is a novel biomarker for predicting poor outcomes and triple-negative status in breast cancer Open
Breast cancer patients’ outcomes have improved dramatically in recent years, but relapses and poor prognosis remain common due to its aggressiveness and heterogeneity. The development of reliable biomarkers is still needed for predicting p…
View article: The Hippo pathway links adipocyte plasticity to adipose tissue fibrosis
The Hippo pathway links adipocyte plasticity to adipose tissue fibrosis Open
Fibrosis disrupts adipose tissue (AT) homeostasis and exacerbates metabolic dysfunction upon chronic caloric excess. The molecular mechanisms linking adipocyte plasticity to AT fibrosis are largely unknown. Here we show that the Hippo path…
View article: Construction of an m6A-related lncRNA model for predicting prognosis and immunotherapy in patients with lung adenocarcinoma
Construction of an m6A-related lncRNA model for predicting prognosis and immunotherapy in patients with lung adenocarcinoma Open
Purpose : This study aimed to explore the role of N6-methyladenosine (m6A)-related lncRNAs in lung adenocarcinoma (LUAD). Methods : Gene expression data and clinical data of LUAD patients were acquired from The Cancer Genome Atlas (TCGA) D…
View article: Correction to: Hsa_circ_0001361 facilitates the progress of lung adenocarcinoma cells via targeting miR-525-5p/VMA21 axis
Correction to: Hsa_circ_0001361 facilitates the progress of lung adenocarcinoma cells via targeting miR-525-5p/VMA21 axis Open
View article: Hsa_circ_0001361 facilitates the progress of lung adenocarcinoma cells via targeting miR-525-5p/VMA21 axis
Hsa_circ_0001361 facilitates the progress of lung adenocarcinoma cells via targeting miR-525-5p/VMA21 axis Open
View article: Combination Therapy of Metastatic Castration-Recurrent Prostate Cancer: Hyaluronic Acid Decorated, Cabazitaxel-Prodrug and Orlistat Co-Loaded Nano-System
Combination Therapy of Metastatic Castration-Recurrent Prostate Cancer: Hyaluronic Acid Decorated, Cabazitaxel-Prodrug and Orlistat Co-Loaded Nano-System Open
ORL/HA-CBZ/LPNs showed remarkable synergism cytotoxicity and the best tumor inhibition efficiency in mice with negligible systemic toxicity. ORL/HA-CBZ/LPNs can be highly useful for targeted prostate cancer therapy.
View article: Synergistic combination therapy of lung cancer using lipid-layered cisplatin and oridonin co-encapsulated nanoparticles
Synergistic combination therapy of lung cancer using lipid-layered cisplatin and oridonin co-encapsulated nanoparticles Open