Huiyan Chen
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View article: Using Folded Proteins as Mechanically Well-Defined Units to Understand Fatigue Fracture in Hydrogels: Bridging Single-Molecule and Bulk Studies
Using Folded Proteins as Mechanically Well-Defined Units to Understand Fatigue Fracture in Hydrogels: Bridging Single-Molecule and Bulk Studies Open
Hydrogels are widely used in applications that require durability under cyclic loading, yet fatigue fracture often limits their reliability. The underlying physical principles of hydrogel fatigue remain elusive due to the complex interplay…
View article: Identity-Based Provable Data Possession with Designated Verifier from Lattices for Cloud Computing
Identity-Based Provable Data Possession with Designated Verifier from Lattices for Cloud Computing Open
Provable data possession (PDP) is a technique that enables the verification of data integrity in cloud storage without the need to download the data. PDP schemes are generally categorized into public and private verification. Public verifi…
View article: Simultaneous Symptom Network Analysis of Heart Failure Patients: A Cross-Sectional Study
Simultaneous Symptom Network Analysis of Heart Failure Patients: A Cross-Sectional Study Open
Intervening with chest pain as the core symptom can effectively reduce the severity of the entire symptom network. Early intervention for symptoms such as lack of energy can alleviate the burden of symptom management. Identifying predictab…
View article: Exploring the Factors Influencing the Spread of COVID-19 Within Residential Communities Using a Big Data Approach: A Case Study of Beijing
Exploring the Factors Influencing the Spread of COVID-19 Within Residential Communities Using a Big Data Approach: A Case Study of Beijing Open
The COVID-19 pandemic has profoundly influenced urban planning and disease management in residential areas. Focusing on Beijing as a case study (3898 communities), this research develops a big data analytics framework integrating anonymize…
View article: Lattice-based ABE with multi-ciphertext equality test in cloud computing
Lattice-based ABE with multi-ciphertext equality test in cloud computing Open
Data is typically encrypted before transmission to a cloud server to safeguard user privacy. However, such encryption prevents the server from performing searches on the data, necessitating the introduction of novel cryptographic primitive…
View article: Overexpression of metalloproteinase PAPPA accelerates cancer progression and correlates with immune cell infiltration in gastric cancer: insights from bioinformatics and in vitro investigations
Overexpression of metalloproteinase PAPPA accelerates cancer progression and correlates with immune cell infiltration in gastric cancer: insights from bioinformatics and in vitro investigations Open
The findings of this investigation suggest that PAPPA serves as a crucial modulator of GC, underscoring its potential as a GC treatment target.
View article: The Overexpression of <scp>RTN4</scp> Significantly Associated With an Unfavourable Prognosis in Patients With Lower‐Grade Gliomas
The Overexpression of <span>RTN4</span> Significantly Associated With an Unfavourable Prognosis in Patients With Lower‐Grade Gliomas Open
Gliomas, the most prevalent primary malignancy of the central nervous system, is characterised by its high mortality rates and unfavourable prognosis. Despite extensive research, the underlying mechanisms of glioma pathogenesis remain elus…
View article: Cancer Cell‐Derived Exosomal miR‐500a‐3p Modulates Hepatic Stellate Cell Activation and the Immunosuppressive Microenvironment
Cancer Cell‐Derived Exosomal miR‐500a‐3p Modulates Hepatic Stellate Cell Activation and the Immunosuppressive Microenvironment Open
Hepatocellular carcinoma (HCC) mainly depends on liver fibrosis/cirrhosis, which is regulated by tumor cells and the tumor microenvironment (TME), and is a crucial factor in tumor progression. This study aimed to identify abnormally expres…
View article: Mechanochemistry: Fundamental Principles and Applications
Mechanochemistry: Fundamental Principles and Applications Open
Mechanochemistry is an emerging research field at the interface of physics, mechanics, materials science, and chemistry. Complementary to traditional activation methods in chemistry, such as heat, electricity, and light, mechanochemistry f…
View article: Yangtze finless porpoise sexual behavior object detection algorithm based on YOLOv8
Yangtze finless porpoise sexual behavior object detection algorithm based on YOLOv8 Open
Traditional studies on Yangtze finless porpoise behavior rely on manual observation mainly, posing challenges such as low efficiency, high labor costs and visual fatigue. To address these issues, the Baiji Dolphinarium at the Institute of …
View article: Efficient iNTRU-based public key authentication keyword searchable encryption in cloud computing
Efficient iNTRU-based public key authentication keyword searchable encryption in cloud computing Open
With the popularity of cloud computing, a large number of personal and corporate data are outsourced to the cloud. This centralized storage and processing mode not only improves the efficiency of data processing, but also brings challenges…
View article: Molecular Force Sensors for Biological Application
Molecular Force Sensors for Biological Application Open
The mechanical forces exerted by cells on their surrounding microenvironment are known as cellular traction forces. These forces play crucial roles in various biological processes, such as tissue development, wound healing and cell functio…
View article: Quality of life and its related-influencing factors in patients with cervical cancer based on the scale QLICP-CE(V2.0)
Quality of life and its related-influencing factors in patients with cervical cancer based on the scale QLICP-CE(V2.0) Open
Background Quality of life research can guide clinical workers to adopt more targeted treatment and intervention measures, so as to achieve the purpose of improving patients’ quality of life. The objective of this study was to evaluate hea…
View article: Efficient Equality Test Technique using Identity-Based Encryption for Telemedicine Systems
Efficient Equality Test Technique using Identity-Based Encryption for Telemedicine Systems Open
Telemedicine systems play an important role in early HIV screening, but data privacy in the medical system has always been a challenging issue. For data privacy in the medical system, using identity encryption-based equivalence testing sch…
View article: A decentralized multi-authority CP-ABE scheme from LWE
A decentralized multi-authority CP-ABE scheme from LWE Open
As a cryptographic primitive supporting finer and richer access control, attribute-based encryption can provide more efficient, concise, secure and highly adaptive access control policies for cloud data, which has attracted the attention o…
View article: Regulation of mechanical force on cardiomyocytes beating
Regulation of mechanical force on cardiomyocytes beating Open
The mechanical behavior of cardiomyocytes plays an essential role in maintaining life and health. It is traditionally believed that both electrical signals and chemical signals modulate the cardiomyocytes behaviors. Recent discoveries have…
View article: Improved Trapdoors and Public Key Search Encryption Based on Middle-Product LWE
Improved Trapdoors and Public Key Search Encryption Based on Middle-Product LWE Open
Middle-product learning with errors (MP-LWE) was proposed in 2017 by Rosa et al., it is considered to be a method that combines the high efficiency of the R-LWE with the security guarantee of the ordinary LWE. Following the idea of this pr…
View article: A CP-ABE Scheme Based on Lattice LWE and Its Security Analysis
A CP-ABE Scheme Based on Lattice LWE and Its Security Analysis Open
In recent years, the research on ciphertext-policy attribute-based encryption (CP-ABE) scheme design based on learning with errors (LWE) has been a challenging problem, and many researchers have made a lot of attempts at it. At EUROCRYPT 2…
View article: Health related quality of life and its influencing factors of socio- demographic and clinical characteristics in patients with cervical cancer based the scale QLICP-CE(V2.0)
Health related quality of life and its influencing factors of socio- demographic and clinical characteristics in patients with cervical cancer based the scale QLICP-CE(V2.0) Open
Background Quality of life research can guide clinical workers to adopt more targeted treatment and intervention measures, so as to achieve the purpose of improving patients' quality of life. The objective of this study was to evaluate hea…
View article: Fast dynamic softening of hydrogels increases endogenous cell forces by accumulating mechanical signalling molecules
Fast dynamic softening of hydrogels increases endogenous cell forces by accumulating mechanical signalling molecules Open
The rigidity of extracellular matrices (ECMs) is an important factor defining cellular mechanotransduction. Under static conditions, cells typically generate higher endogenous forces on stiff substrates than on soft substrates. However, as…
View article: Association of osteoporosis risk and polymorphisms of osteoprotegerin gene T950C in postmenopausal Chinese women: A PRISMA-compliant meta-analysis
Association of osteoporosis risk and polymorphisms of osteoprotegerin gene T950C in postmenopausal Chinese women: A PRISMA-compliant meta-analysis Open
Background: This study aimed to assess the association between the T950C polymorphism and osteoporosis in postmenopausal Chinese women to further reduce the influence of different genetic backgrounds by meta-analysis and subgroup analysis.…
View article: A Hierarchical Multi-Vehicle Coordinated Motion Planning Method based on Interactive Spatio-Temporal Corridors
A Hierarchical Multi-Vehicle Coordinated Motion Planning Method based on Interactive Spatio-Temporal Corridors Open
Multi-vehicle coordinated motion planning has always been challenged to safely and efficiently resolve conflicts under non-holonomic dynamic constraints. Constructing spatial-temporal corridors for multi-vehicle can decouple the high-dimen…
View article: Dehazed Image Quality Evaluation: From Partial Discrepancy to Blind Perception
Dehazed Image Quality Evaluation: From Partial Discrepancy to Blind Perception Open
Image dehazing aims to restore spatial details from hazy images. There have emerged a number of image dehazing algorithms, designed to increase the visibility of those hazy images. However, much less work has been focused on evaluating the…
View article: Gradual Stress-Relaxation of Hydrogel Regulates Cell Spreading
Gradual Stress-Relaxation of Hydrogel Regulates Cell Spreading Open
There is growing evidence that the mechanical properties of extracellular matrices (ECMs), including elasticity and stress-relaxation, greatly influence the function and form of the residing cells. However, the effects of elasticity and st…
View article: Generation and Selection of Driver-Behavior-Based Transferable Motion Primitives
Generation and Selection of Driver-Behavior-Based Transferable Motion Primitives Open
To integrate driver experience and heterogeneous vehicle platform characteristics in a motion-planning algorithm, based on the driver-behavior-based transferable motion primitives (MPs), a general motion-planning framework for offline gene…
View article: Clinical Impact of X-Ray Repair Cross-Complementary 1 (XRCC1) and the Immune Environment in Colorectal Adenoma–Carcinoma Pathway Progression
Clinical Impact of X-Ray Repair Cross-Complementary 1 (XRCC1) and the Immune Environment in Colorectal Adenoma–Carcinoma Pathway Progression Open
Increased IEL density and PD-1/PD-L1 expression correlate with cytological dysplasia progression and specifically with the XRCC1 mutation status in CRC. Our findings support a stepwise dysplasia-carcinoma sequence of adenoma carcinogenesis…