Huiyan Shi
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View article: CUSP06, a Novel CDH6-Targeted Antibody-Drug Conjugate, Demonstrates Antitumor Efficacy in Multiple CDH6-Expressing Human Cancer Models
CUSP06, a Novel CDH6-Targeted Antibody-Drug Conjugate, Demonstrates Antitumor Efficacy in Multiple CDH6-Expressing Human Cancer Models Open
Background/Objectives: Cadherin-6 (CDH6), also known as K-cadherin, is a type II classic cadherin molecule that plays an important role in the embryonic development of the kidney but has very limited expression in adult tissues. It is over…
View article: Treatment for peripheral nerve injury: a protocol for a systematic review and Bayesian network meta-analysis
Treatment for peripheral nerve injury: a protocol for a systematic review and Bayesian network meta-analysis Open
Introduction Available therapies for peripheral nerve injury (PNI) include surgical and non-surgical treatments. Surgical treatment includes neurorrhaphy, grafting (allografts and autografts) and tissue-engineered grafting (artificial nerv…
View article: Application and underlying mechanism of acupuncture for the nerve repair after peripheral nerve injury: remodeling of nerve system
Application and underlying mechanism of acupuncture for the nerve repair after peripheral nerve injury: remodeling of nerve system Open
Peripheral nerve injury (PNI) is a structural event with harmful consequences worldwide. Due to the limited intrinsic regenerative capacity of the peripheral nerve in adults, neural restoration after PNI is difficult. Neurological remodeli…
View article: “Tong Guan Li Qiao” Acupuncture Therapy on Post-Stroke Dysphagia
“Tong Guan Li Qiao” Acupuncture Therapy on Post-Stroke Dysphagia Open
The differences between the “Tong Guan Li Qiao” acupuncture therapy and the conventional and current other acupuncture methods for poststroke dysphagia are as follows: first, it adheres to the basic idea of “Xing Nao Kai Qiao” acupuncture …
View article: Acupuncture for Hypertension in Animal Models: A Systematic Review and Meta-Analysis
Acupuncture for Hypertension in Animal Models: A Systematic Review and Meta-Analysis Open
Objective. The aim of this study was to summarize and evaluate the efficacy of acupuncture in hypertension animal study. Methods. Studies were searched from six databases, including Medline, Embase, Chinese National Knowledge Infrastructur…
View article: Neural stem cell therapy for brain disease
Neural stem cell therapy for brain disease Open
Brain diseases, including brain tumors, neurodegenerative disorders, cerebrovascular diseases, and traumatic brain injuries, are among the major disorders influencing human health, currently with no effective therapy. Due to the low regene…
View article: Research on Vocational Education Strategies Based on Enterprise Demand
Research on Vocational Education Strategies Based on Enterprise Demand Open
In recent years, enterprises’ demand for talents has undergone significant changes, enterprises not only require talents have professional skills, but also require talents have high overall quality, in order to meet the demand of high-qual…
View article: Acupuncture accelerates neural regeneration and synaptophysin production after neural stem cells transplantation in mice
Acupuncture accelerates neural regeneration and synaptophysin production after neural stem cells transplantation in mice Open
Acupuncture may promote nerve regeneration and synaptogenesis in SAMP8 mice by regulating the microenvironment of NSC transplantation to improve the nerve activity and promote the recovery of AD-damaged cells.
View article: miR-22 exerts anti-alzheimic effects via the regulation of apoptosis of hippocampal neurons
miR-22 exerts anti-alzheimic effects via the regulation of apoptosis of hippocampal neurons Open
To investigate the expression of miR-22 in the hippocampus of amyloid β (1-42)-induced alzheimic rats, and to assess the underlying mechanism. A total of 60 male Sprague Dawley rats weighing between 274.65 and 293.97 g (mean weight = 284.…
View article: Combined acupuncture and HuangDiSan treatment affects behavior and synaptophysin levels in the hippocampus of senescence-accelerated mouse prone 8 after neural stem cell transplantation
Combined acupuncture and HuangDiSan treatment affects behavior and synaptophysin levels in the hippocampus of senescence-accelerated mouse prone 8 after neural stem cell transplantation Open
Sanjiao acupuncture and HuangDiSan can promote the proliferation, migration and differentiation of exogenous neural stem cells in senescence-accelerated mouse prone 8 (SAMP8) mice and can improve learning and memory impairment and behavior…
View article: Simultaneous Determination of Five Specific and Sensitive Nephrotoxicity Biomarkers in Serum and Urine Samples of Four Drug-Induced Kidney Injury Models
Simultaneous Determination of Five Specific and Sensitive Nephrotoxicity Biomarkers in Serum and Urine Samples of Four Drug-Induced Kidney Injury Models Open
In clinical diagnosis, serum creatinine (CR) was commonly used as the routine markers for the evaluation of kidney injury. To investigate the specific and sensitive nephrotoxicity biomarkers in different drug-induced kidney injury (DKI) mo…
View article: Influence of pretreatment of piperazine ferulate on pharmacokinetic parameters of methotrexate in methotrexate-induced renal injury model rats by HPLC-MS
Influence of pretreatment of piperazine ferulate on pharmacokinetic parameters of methotrexate in methotrexate-induced renal injury model rats by HPLC-MS Open
The present study was designed to investigate the influence of the pretreatment of piperazine ferulate on pharmacokinetic parameters of methotrexate in methotrexate-induced renal injury rats. A simple and efficient high performance liquid …