Huiyan Ye
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View article: A Learner‐Centred Exploration of Teachers' Solution Pathways in K‐12 Programming‐Based Mathematical Problem‐Solving
A Learner‐Centred Exploration of Teachers' Solution Pathways in K‐12 Programming‐Based Mathematical Problem‐Solving Open
Background Empirical studies have revealed students' development of computational thinking (CT) and mathematical thinking (MT) during programming‐based mathematical problem‐solving, highlighting specific CT concepts or practices that serve…
View article: Integrating Artificial Intelligence and Computational Thinking in Educational Contexts: A Systematic Review of Instructional Design and Student Learning Outcomes
Integrating Artificial Intelligence and Computational Thinking in Educational Contexts: A Systematic Review of Instructional Design and Student Learning Outcomes Open
A growing body of research is focusing on integrating artificial intelligence (AI) and computational thinking (CT) to enhance student learning outcomes. Many researchers have designed instructional activities to achieve various learning go…
View article: Examining mathematics teachers’ creative actions in programming-based mathematical activities
Examining mathematics teachers’ creative actions in programming-based mathematical activities Open
There has been a renewed interest in creativity as a twenty-first century skill in K-12 mathematics education. However, previous research has paid less attention to creative actions than to other learning outcomes, which are often product-…
View article: ScholarOne - Integrating Artificial Intelligence and Computational Thinking in Educational Contexts: A Systematic Review of Instructional Design and Student Learning Outcomes
ScholarOne - Integrating Artificial Intelligence and Computational Thinking in Educational Contexts: A Systematic Review of Instructional Design and Student Learning Outcomes Open
A growing body of research is focusing on integrating artificial intelligence (AI) and computational thinking (CT) to enhance student learning outcomes. Many researchers have designed instructional activities to achieve various learning go…
View article: Integration of computational thinking in K-12 mathematics education: a systematic review on CT-based mathematics instruction and student learning
Integration of computational thinking in K-12 mathematics education: a systematic review on CT-based mathematics instruction and student learning Open
There has been substantial research undertaken on the integration of computational thinking (CT) in K-12 mathematics education in recent years, particularly since 2018 when relevant systematic reviews were conducted on the topic. Many empi…
View article: Hydrocarbon Dew Point Measurement and Model Evaluation of Synthetic and Real Natural Gases
Hydrocarbon Dew Point Measurement and Model Evaluation of Synthetic and Real Natural Gases Open
Hydrocarbon dew point (HCDP) is one of the most important quality specifications of natural gas. Measuring and predicting the HCDP accurately are essential for the natural gas industry. However, the comprehensive experimental HCDP curve da…
View article: Phylogeny of MCR-1.
Phylogeny of MCR-1. Open
The method of maximum likelihood tree is applied here. The scale bar corresponds to a 100% difference in compared residues, on average, per branch length. The members in this phylogenetic tree can be grouped into two clades (one is annotat…
View article: Scheme for the two <i>mcr</i>-<i>1</i>-harbouring plasmids pE15004 and pE15017.
Scheme for the two <i>mcr</i>-<i>1</i>-harbouring plasmids pE15004 and pE15017. Open
A. Genomic map of the mcr-1-containing IncX4-type plasmid pE15004 from the human gut microbiota. B. Genomic map of the MCR-1 and ESBL-coproducing IncI2-type plasmid pE15017 from the human gut microbiota. Circles from inside to outside indi…
View article: Structure-guided determination of five important residues for MCR-1 mediated colistin resistance.
Structure-guided determination of five important residues for MCR-1 mediated colistin resistance. Open
A. The modeled ribbon structure for PEA-lipid A transferase domain of the membrane-bound MCR-1 protein. The ribbon structure was given via PyMol software. The key residues proposed by structural docking is indicated with red rectangle. B. …
View article: Dissemination and Mechanism for the MCR-1 Colistin Resistance
Dissemination and Mechanism for the MCR-1 Colistin Resistance Open
Polymyxins are the last line of defense against lethal infections caused by multidrug resistant Gram-negative pathogens. Very recently, the use of polymyxins has been greatly challenged by the emergence of the plasmid-borne mobile colistin…
View article: Functional definition of BirA suggests a biotin utilization pathway in the zoonotic pathogen Streptococcus suis
Functional definition of BirA suggests a biotin utilization pathway in the zoonotic pathogen Streptococcus suis Open
Biotin protein ligase is universal in three domains of life. The paradigm version of BPL is the Escherichia coli BirA that is also a repressor for the biotin biosynthesis pathway. Streptococcus suis , a leading bacterial agent for swine di…
View article: Deciphering a unique biotin scavenging pathway with redundant genes in the probiotic bacterium Lactococcus lactis
Deciphering a unique biotin scavenging pathway with redundant genes in the probiotic bacterium Lactococcus lactis Open
Biotin protein ligase (BPL) is widespread in the three domains of the life. The paradigm BPL is the Escherichia coli BirA protein, which also functions as a repressor for the biotin biosynthesis pathway. Here we report that Lactococcus lac…
View article: Loss of 89K Pathogenicity Island in Epidemic<i>Streptococcus suis</i>, China
Loss of 89K Pathogenicity Island in Epidemic<i>Streptococcus suis</i>, China Open
To the Editor: Streptococcus suis serotype 2 (SS2) is a previously neglected, newly emerging human pathogen that causes occupational and opportunistic infections (1,2). Outbreaks of fatal human SS2 infections in China, featuring streptococ…
View article: Diversified <i>mcr-1</i> -Harbouring Plasmid Reservoirs Confer Resistance to Colistin in Human Gut Microbiota
Diversified <i>mcr-1</i> -Harbouring Plasmid Reservoirs Confer Resistance to Colistin in Human Gut Microbiota Open
Colistin is an ultimate line of refuge against multidrug-resistant Gram-negative pathogens. Very recently, the emergence of plasmid-mediated mcr-1 colistin resistance has become a great challenge to global public health, raising the possib…