Huiyoung Kwon
YOU?
Author Swipe
View article: Increases in brain catecholamine levels counteract memory deficits and reduces Aβ deposition in 5XFAD male mice
Increases in brain catecholamine levels counteract memory deficits and reduces Aβ deposition in 5XFAD male mice Open
Alzheimer's disease (AD) is a degenerative brain disease that presents with neurological symptoms and memory loss, with no clear treatment. Catecholamines, including dopamine, epinephrine, and norepinephrine, can inhibit or degrade the abn…
View article: The Potential Effects of 2,3,4-Trihydroxybenzophenone on the Transient Cerebral Ischemic Stroke in Male Mice
The Potential Effects of 2,3,4-Trihydroxybenzophenone on the Transient Cerebral Ischemic Stroke in Male Mice Open
Acute ischemic stroke is a cerebrovascular disease associated with high mortality and severe aftereffects which is caused by the blockage of cerebral blood vessels by a thrombus or embolus. Treatments for this condition are extremely limit…
View article: Phyllodulcin improves hippocampal long-term potentiation in 5XFAD mice
Phyllodulcin improves hippocampal long-term potentiation in 5XFAD mice Open
Alzheimer's disease (AD) is a well-known neurodegenerative brain disease, and no curative treatment has yet been developed. The main symptoms include various brain lesions, caused by amyloid β (Aβ) aggregation, and cognitive decline. There…
View article: Eugenitol ameliorates memory impairments in 5XFAD mice by reducing Aβ plaques and neuroinflammation
Eugenitol ameliorates memory impairments in 5XFAD mice by reducing Aβ plaques and neuroinflammation Open
Alzheimer’s disease (AD) is caused by various pathological mechanisms; therefore, it is necessary to develop drugs that simultaneously act on multiple targets. In this study, we investigated the effects of eugenitol, which has anti-amyloid…
View article: Role of extracellular signal-regulated kinase in rubrofusarin-enhanced cognitive functions and neurite outgrowth
Role of extracellular signal-regulated kinase in rubrofusarin-enhanced cognitive functions and neurite outgrowth Open
Memory-enhancing agents have long been required for various reasons such as for obtaining a good score in a test in the young and for retaining memory in the aged. Although many studies have found that several natural products may be good …
View article: Hydrangea macrophylla and Thunberginol C Attenuate Stress-Induced Anxiety in Mice
Hydrangea macrophylla and Thunberginol C Attenuate Stress-Induced Anxiety in Mice Open
Stress is an important neurological input for successful life. However, chronic stress and stress hormones could be a cause of various neurological disorders including anxiety disorders. Therefore, there have been many efforts to find effe…
View article: REDD1 Is Involved in Amyloid β-Induced Synaptic Dysfunction and Memory Impairment
REDD1 Is Involved in Amyloid β-Induced Synaptic Dysfunction and Memory Impairment Open
Alzheimer’s disease (AD) is a neurodegenerative disease characterized by neurological dysfunction, including memory impairment, attributed to the accumulation of amyloid β (Aβ) in the brain. Although several studies reported possible mecha…
View article: Rubrofusarin Attenuates Chronic Restraint Stress-Induced Depressive Symptoms
Rubrofusarin Attenuates Chronic Restraint Stress-Induced Depressive Symptoms Open
The aim of this study was to examine whether rubrofusarin, an active ingredient of the Cassia species, has an antidepressive effect in chronic restraint stress (CRS) mouse model. Although acute treatment using rubrofusarin failed, chronic …
View article: The effect of maslinic acid on cognitive dysfunction induced by cholinergic blockade in mice
The effect of maslinic acid on cognitive dysfunction induced by cholinergic blockade in mice Open
Background and Purpose Alzheimer's disease (AD) is the most prevalent disease associated with cognitive dysfunction. Current AD therapeutic agents have several gastrointestinal or psychological adverse effects and therefore, novel therapeu…
View article: β-Amyrin Ameliorates Alzheimer's Disease-Like Aberrant Synaptic Plasticity in the Mouse Hippocampus
β-Amyrin Ameliorates Alzheimer's Disease-Like Aberrant Synaptic Plasticity in the Mouse Hippocampus Open
Alzheimer's disease (AD) is a progressive and most frequently diagnosed neurodegenerative disorder. However, there is still no drug preventing the progress of this disorder. β-Amyrin, an ingredient of the surface wax of tomato fruit and da…
View article: The Seed of <i>Zizyphus jujuba</i> var. <i>spinosa</i> Attenuates Alzheimer’s Disease-Associated Hippocampal Synaptic Deficits through BDNF/TrkB Signaling
The Seed of <i>Zizyphus jujuba</i> var. <i>spinosa</i> Attenuates Alzheimer’s Disease-Associated Hippocampal Synaptic Deficits through BDNF/TrkB Signaling Open
Ziziphus jujuba is a plant, which bears fruits and seeds that are used for medicinal purposes in Traditional oriental medicine. The seed of Zizyphus jujuba var. spinosa (EZJ) has been also traditionally used for psychiatric disorders in Ch…
View article: Echinocystic Acid Facilitates Neurite Outgrowth in Neuroblastoma Neuro2a Cells and Enhances Spatial Memory in Aged Mice
Echinocystic Acid Facilitates Neurite Outgrowth in Neuroblastoma Neuro2a Cells and Enhances Spatial Memory in Aged Mice Open
Aging leads to functional changes in the brain and decreases ability of learning and memory. Neurite outgrowth is important in learning and memory, therefore regulation of neurite outgrowth might be a candidate for treating aged brain. Ech…