Huma Rafiq
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View article: STAT3 Inhibition in Cancer: A Review of Emerging Therapeutics
STAT3 Inhibition in Cancer: A Review of Emerging Therapeutics Open
Abnormal signal transducer and transcriptional activator (STAT3) activation occurs in many human tumors. Therefore, targeting STAT3 signaling has emerged as a promising therapeutic approach for treating many cancers. In addition, studies u…
View article: A Novel Treatment for Scabies with Herbal Formulation: A Clinical Safety Assessment Study
A Novel Treatment for Scabies with Herbal Formulation: A Clinical Safety Assessment Study Open
Introduction: Scabies, known as Jarb in Unani medicine, is a parasitic infection caused by the mite Sarcoptes scabiei var. Hominis. It is characterized by intense itching, particularly noted by patients at night. In India, this disease aff…
View article: PRECONDITIONING OF STEM CELLS WITH SILVER NANOPARTICLES CAN REDUCE LIVER FIBROSIS IN MICE
PRECONDITIONING OF STEM CELLS WITH SILVER NANOPARTICLES CAN REDUCE LIVER FIBROSIS IN MICE Open
Liver fibrosis is the seven largest cause of death worldwide. Human life is very dangerously threatened by advanced liver fibrosis, which has a high morbidity and fatality rate. The only widely approved treatment option for those with seve…
View article: Biooriented Synthesis of Ibuprofen-Clubbed Novel <i>Bis</i>-Schiff Base Derivatives as Potential Hits for Malignant Glioma: <i>In Vitro</i> Anticancer Activity and <i>In Silico</i> Approach
Biooriented Synthesis of Ibuprofen-Clubbed Novel <i>Bis</i>-Schiff Base Derivatives as Potential Hits for Malignant Glioma: <i>In Vitro</i> Anticancer Activity and <i>In Silico</i> Approach Open
This research work is based on the synthesis of bis-Schiff base derivatives of the commercially available ibuprofen drug in outstanding yields through multistep reactions. Structures of the synthesized compounds were confirmed by the help …
View article: Identification of novel STAT3 inhibitors for liver fibrosis, using pharmacophore-based virtual screening, molecular docking, and biomolecular dynamics simulations
Identification of novel STAT3 inhibitors for liver fibrosis, using pharmacophore-based virtual screening, molecular docking, and biomolecular dynamics simulations Open
The signal transducer and activator of transcription 3 (STAT3) plays a fundamental role in the growth and regulation of cellular life. Activation and over-expression of STAT3 have been implicated in many cancers including solid blood tumor…
View article: Trends in the Magnitude of NCDs among Schedule Tribe Population of Kashmir with Special Reference to Health and Nutritional
Trends in the Magnitude of NCDs among Schedule Tribe Population of Kashmir with Special Reference to Health and Nutritional Open
The rising trend in NCD here consonance unremitting surveillance and awareness amongst population.This study aims at access the health and nutritional estimation of Schedule tribes, besides the subject recognition regarding on-communicable…
View article: Combinatorial Therapeutic Potential of Stem Cells and Benzimidazol Derivatives for the Reduction of Liver Fibrosis
Combinatorial Therapeutic Potential of Stem Cells and Benzimidazol Derivatives for the Reduction of Liver Fibrosis Open
(1) Background: Liver fibrosis is currently one of the top ten causes of death worldwide. Stem cells transplantation using mesenchymal stem cells (MSCs) is an alternative therapy which is used in the place of organ transplant, due to the i…
View article: LAWS DEALING WITH FOOD SAFETY LAWS IN PAKISTAN
LAWS DEALING WITH FOOD SAFETY LAWS IN PAKISTAN Open
There have been 62784 fatalities and 1,133,788 confirmed cases of the 2019 coronavirus illness (COVID19), which has spread to 181 nations and territories. COVID-19 is a pandemic that began in China in December 2019. World health organizati…