Dang Khoa Nguyen
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View article: Operation and Design of Dirac-Source FETs Using Ab Initio Transport Simulations: Subthreshold Swing and Drive Current
Operation and Design of Dirac-Source FETs Using Ab Initio Transport Simulations: Subthreshold Swing and Drive Current Open
This article investigates the operation and design of Dirac-source FETs (DSFETs), by using ab initio transport simulations based on the NEGF formalism, which seems appropriate given the novelty of the physics and of the device architecture…
View article: Assessment of a biometric shirt for sleep body position identification in epilepsy
Assessment of a biometric shirt for sleep body position identification in epilepsy Open
Background Patients with uncontrolled epilepsy are at increased risk of sudden unexpected death in epilepsy (SUDEP). Evidence suggests that sleeping prone or being in a prone position after a seizure may increase the risk of SUDEP. A few w…
View article: Detection of focal impaired awareness seizures using a biometric shirt
Detection of focal impaired awareness seizures using a biometric shirt Open
Objective In recent years, seizure detection using wearable technology has gained significant attention in research. Most studies, however, have focused on detecting generalized or focal to bilateral tonic–clonic seizures. This study evalu…
View article: Insular Cortex Modulation by Repetitive Transcranial Magnetic Stimulation with Concurrent Functional Magnetic Resonance Imaging: Preliminary Findings
Insular Cortex Modulation by Repetitive Transcranial Magnetic Stimulation with Concurrent Functional Magnetic Resonance Imaging: Preliminary Findings Open
Background/Objectives: The insula is a deep, functionally heterogeneous region involved in various pathological conditions. Repetitive transcranial magnetic stimulation (rTMS) has emerged as a promising therapeutic avenue for neuromodulati…
View article: Separating Subjective from Objective Food Value in the Human Insula: An Exploratory Study Using Intracranial EEG
Separating Subjective from Objective Food Value in the Human Insula: An Exploratory Study Using Intracranial EEG Open
Background/Objectives: The human insula is a key structure implicated in integrating internal states and external food cues, yet its precise role remains unclear, in part due to the temporal limitations of neuroimaging techniques like fMRI…
View article: Insular Cortex Modulation by Repetitive Transcranial Magnetic Stimulation with Concurrent Functional Magnetic Resonance Imaging: Preliminary Findings
Insular Cortex Modulation by Repetitive Transcranial Magnetic Stimulation with Concurrent Functional Magnetic Resonance Imaging: Preliminary Findings Open
Background/Objectives: The insula plays a role in various medical conditions, including eating disorders, addiction, and chronic pain. Repetitive transcranial magnetic stimulation (rTMS) has emerged as a promising therapeutic avenue, yet f…
View article: Microelectrode Implantation in Human Insula: Technical Challenges and Recording Insights
Microelectrode Implantation in Human Insula: Technical Challenges and Recording Insights Open
Background/Objectives: Intracranial macroelectrode implantation is a pivotal clinical tool in the evaluation of drug-resistant epilepsy, allowing further insights into the localization of the epileptogenic zone and the delineation of eloqu…
View article: Preictal connectivity dynamics: Exploring inflow and outflow in iEEG networks
Preictal connectivity dynamics: Exploring inflow and outflow in iEEG networks Open
Introduction: Focal resective surgery can be an effective treatment option for patients with refractory epilepsy if the seizure onset zone is accurately identied through intracranial EEG recordings. The traditional concept of the epileptog…
View article: Microelectrode Implantation in Human Insula: Technical Challenges and Recording Insights
Microelectrode Implantation in Human Insula: Technical Challenges and Recording Insights Open
Background/Objectives: Intracranial macroelectrode implantation is a pivotal clinical tool in the evaluation of drug-resistant epilepsy, allowing further insights into the localization of the epileptogenic zone and the delineation of eloqu…
View article: Novel analogous tasks to assess material-specific memory impairments associated with temporal lobe epilepsy
Novel analogous tasks to assess material-specific memory impairments associated with temporal lobe epilepsy Open
Episodic memory tasks employing verbal material are generally sensitive to material-specific memory impairments in individuals with left mesial temporal lobe epilepsy (LTLE), whereas visuospatial memory tasks are less consistently failed b…
View article: Contribution of the Brown Location Test to the pre-surgical neuropsychological assessment of temporal lobe epilepsy
Contribution of the Brown Location Test to the pre-surgical neuropsychological assessment of temporal lobe epilepsy Open
The nature of memory deficits in mesial temporal lobe epilepsy (mTLE) can depend on the side of the epileptogenic zone (EZ). Although left mTLE has been consistently associated with impairments in verbal memory, the association between rig…
View article: Improving diagnostic accuracy of routine EEG for epilepsy using deep learning
Improving diagnostic accuracy of routine EEG for epilepsy using deep learning Open
The yield of routine EEG to diagnose epilepsy is limited by low sensitivity and the potential for misinterpretation of interictal epileptiform discharges. Our objective is to develop, train and validate a deep learning model that can ident…
View article: Cortical hemodynamics of electrographic status epilepticus in the critically ill
Cortical hemodynamics of electrographic status epilepticus in the critically ill Open
Objectives The pathophysiological mechanisms of status epilepticus (SE) underlying potential brain injury remain largely unclear. This study aims to employ functional near‐infrared spectroscopy (fNIRS) combined with video‐electroencephalog…
View article: <i>Parvimonas micra</i> -polarized M2-like tumor-associated macrophages accelerate colorectal cancer development via IL-8 secretion
<i>Parvimonas micra</i> -polarized M2-like tumor-associated macrophages accelerate colorectal cancer development via IL-8 secretion Open
Parvimonas micra (Pm), a periodontal pathogen, has been implicated in the impairment of anti-tumor responses in colorectal cancer (CRC). The tumor microenvironment in CRC involves tumor-associated macrophages (TAMs), which are pivotal in m…
View article: Sub-60mV/dec Swing and Drive Current in Dirac-Source FETs: A Design Study Based on First-Principle Transport Simulations
Sub-60mV/dec Swing and Drive Current in Dirac-Source FETs: A Design Study Based on First-Principle Transport Simulations Open
By using a modelling framework consisting of NEGF-based ab-initio simulations, we investigate the operation and design of Dirac-Source FETs (DSFETs). First, we discuss some methodological aspects that we found pivotal to observe the sub-60…
View article: Outcome of Surgery for Hypothalamic Hamartoma-Related Epilepsy
Outcome of Surgery for Hypothalamic Hamartoma-Related Epilepsy Open
MRgLITT and RFTC offer superior efficacy and safety compared with open microsurgery and should be considered as first-line options. Despite its lower efficacy, SRS is associated with few reported long-term complications, making it a viable…
View article: X‐Linked Bilateral Polymicrogyria With Epilepsy and Intellectual Disability Associated With a Novel <scp><i>KIF4A</i></scp> Variant
X‐Linked Bilateral Polymicrogyria With Epilepsy and Intellectual Disability Associated With a Novel <span><i>KIF4A</i></span> Variant Open
We studied three brothers and a maternal half‐brother featuring global developmental delay, mild to moderate intellectual disability, epilepsy, microcephaly, and strabismus. All had bilateral perisylvian and perirolandic polymicrogyria, wh…
View article: Intervention time and adverse events in a canadian epilepsy monitoring unit: An updated audit
Intervention time and adverse events in a canadian epilepsy monitoring unit: An updated audit Open
This prospective evaluation revealed a small but non-negligible rate of complications in our EMU, higher than our prior retrospective audit. Heightened levels of supervision in our new single-floor EMU led to higher IR. This may have led t…
View article: Progressive remodeling of structural networks following surgery for operculo-insular epilepsy
Progressive remodeling of structural networks following surgery for operculo-insular epilepsy Open
Introduction Operculo-insular epilepsy (OIE) is a rare condition amenable to surgery in well-selected cases. Despite the high rate of neurological complications associated with OIE surgery, most postoperative deficits recover fully and rap…
View article: Resting-State Functional Connectivity Profile of Insular Subregions
Resting-State Functional Connectivity Profile of Insular Subregions Open
The insula is often considered the fifth lobe of the brain and is increasingly recognized as one of the most connected regions in the brain, with widespread connections to cortical and subcortical structures. As a follow-up to our previous…
View article: Epileptic seizure forecasting with wearable‐based nocturnal sleep features
Epileptic seizure forecasting with wearable‐based nocturnal sleep features Open
Objective Non‐invasive biomarkers have recently shown promise for seizure forecasting in people with epilepsy. In this work, we developed a seizure‐day forecasting algorithm based on nocturnal sleep features acquired using a smart shirt. M…
View article: Performance, impact and experiences of using wearable devices for seizure detection in community-based settings: a mixed methods systematic review
Performance, impact and experiences of using wearable devices for seizure detection in community-based settings: a mixed methods systematic review Open
There is low quality scientific evidence supporting the performance of WDD in a home environment. Although qualitative findings support the positive impacts of wearable devices for patients and caregivers, more quantitative studies are nee…
View article: Demographics of Adults With Obstructive Sleep Apnea Who Undergo Nasal Surgery
Demographics of Adults With Obstructive Sleep Apnea Who Undergo Nasal Surgery Open
Objective To assess the demographic characteristics between adult obstructive sleep apnea (OSA) patients who did and did not undergo nasal surgery (NS). Study Design Retrospective cohort study. Setting Kaiser Permanente Northern California…
View article: Outcome of emergency neurosurgery in patients with refractory and super-refractory status epilepticus: a systematic review and individual participant data meta-analysis
Outcome of emergency neurosurgery in patients with refractory and super-refractory status epilepticus: a systematic review and individual participant data meta-analysis Open
Background Refractory (RSE) and super-refractory status epilepticus (SRSE) are serious neurological conditions requiring aggressive management. Beyond anesthetic agents, there is a lack of evidence guiding management in these patients. Thi…
View article: Detection of focal to bilateral tonic–clonic seizures using a connected shirt
Detection of focal to bilateral tonic–clonic seizures using a connected shirt Open
Objective This study was undertaken to develop and evaluate a machine learning‐based algorithm for the detection of focal to bilateral tonic–clonic seizures (FBTCS) using a novel multimodal connected shirt. Methods We prospectively recruit…
View article: iVR-fNIRS: studying brain functions in a fully immersive virtual environment
iVR-fNIRS: studying brain functions in a fully immersive virtual environment Open
Immersive virtual reality (iVR) employs head-mounted displays or cave-like environments to create a sensory-rich virtual experience that simulates the physical presence of a user in a digital space. The technology holds immense promise in …
View article: Evaluation of Commercially Available Seizure Detection Wearables in Canada: Current Evidence
Evaluation of Commercially Available Seizure Detection Wearables in Canada: Current Evidence Open
Wearable-based seizure detection devices hold promise in reducing seizure-related adverse events and relieving the daily stress experienced by people with epilepsy. In this work, we present the latest evidence regarding the performance of …
View article: Stimulating the cingulate to move
Stimulating the cingulate to move Open
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