Hung Huynh
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View article: Codify and Localize Lesions on a Coronary Acoustic Map: Scientific Rationale, Trial Design and Artificial Intelligence Algorithm Protocols
Codify and Localize Lesions on a Coronary Acoustic Map: Scientific Rationale, Trial Design and Artificial Intelligence Algorithm Protocols Open
In coronary artery disease (CAD), the initiation, progression, and regression of atherosclerosis remain incompletely understood, limiting the effectiveness of specific diagnostic and personalized medicine management strategies based on cur…
View article: DeepGPT-DILI: Integrating Graph Convolutional Networks and Large Language Model Embeddings for Accurate Drug-Induced Liver Injury Prediction
DeepGPT-DILI: Integrating Graph Convolutional Networks and Large Language Model Embeddings for Accurate Drug-Induced Liver Injury Prediction Open
View article: Reactivation of the PI3K/mTOR Signaling Pathway Confers Resistance to the FGFR4 Inhibitor FGF401
Reactivation of the PI3K/mTOR Signaling Pathway Confers Resistance to the FGFR4 Inhibitor FGF401 Open
Hepatocellular carcinoma (HCC) is a deadly liver cancer characterized by dysregulated signaling and aberrant cell-cycle control. The FGFR4/FGF19 pathway is dysregulated in HCC and other cancers. Inhibitors targeting the FGF19/FGFR4 pathway…
View article: Minimally invasive surgery for bilateral large basal ganglia hemorrhage: a rare case report and insights from literature
Minimally invasive surgery for bilateral large basal ganglia hemorrhage: a rare case report and insights from literature Open
This case underscores the importance of prompt diagnosis and intervention in bilateral basal ganglia hemorrhage. MIS offers a viable therapeutic option that may enhance recovery while reducing surgical risks.
View article: Effectiveness of web-based education program on knowledge, coping, burden, and quality of life among colorectal cancer caregivers in Vietnam: a quasi-experimental study
Effectiveness of web-based education program on knowledge, coping, burden, and quality of life among colorectal cancer caregivers in Vietnam: a quasi-experimental study Open
View article: Isolation and selection of lipase-producing bacteria from restaurant wastewater
Isolation and selection of lipase-producing bacteria from restaurant wastewater Open
View article: Ảnh hương cua đô kiêm lên tăng trương va ty lê sông cua tôm su (Penaeus monodon) giai đoạn ương giống băng công nghê biofloc
Ảnh hương cua đô kiêm lên tăng trương va ty lê sông cua tôm su (Penaeus monodon) giai đoạn ương giống băng công nghê biofloc Open
Nghiên cứu nhằm xác định độ kiềm thích hợp lên tăng trưởng và tỷ lệ sống của tôm sú (Penaeus monodon) giống ương theo công nghệ biofloc, thí nghiệm gồm 4 nghiệm thức độ kiềm: 80, 120, 160 và 200 mgCaCO3/L. Tôm giống có khối lượng 0,01 g/co…
View article: The mixture of Ganoderma lucidum and Cordyceps militaris: Chemical composition and protective effect against oxidative stress
The mixture of Ganoderma lucidum and Cordyceps militaris: Chemical composition and protective effect against oxidative stress Open
There is a growing demand for the consumption of medicinal mushrooms and their products. Ganoderma lucidum and Cordyceps militaris are two important medicinal mushrooms with significant pharmacological activities. In this study, we aim to …
View article: Vinorelbine Improves the Efficacy of Sorafenib against Hepatocellular Carcinoma: A Promising Therapeutic Approach
Vinorelbine Improves the Efficacy of Sorafenib against Hepatocellular Carcinoma: A Promising Therapeutic Approach Open
Hepatocellular carcinoma (HCC) is a leading global cause of cancer-related mortality. Despite the widespread adoption of sorafenib as the standard HCC treatment, its efficacy is constrained, frequently encountering resistance. To augment t…
View article: Everolimus Acts in Synergy with Vinorelbine to Suppress the Growth of Hepatocellular Carcinoma
Everolimus Acts in Synergy with Vinorelbine to Suppress the Growth of Hepatocellular Carcinoma Open
Hepatocellular carcinoma (HCC) is a challenging cancer to treat, as traditional chemotherapies have shown limited effectiveness. The mammalian target of rapamycin/sirolimus (mTOR) and microtubules are prominent druggable targets for HCC. I…
View article: Supplementary Figure S6 from MEK Inhibition Overcomes Cisplatin Resistance Conferred by SOS/MAPK Pathway Activation in Squamous Cell Carcinoma
Supplementary Figure S6 from MEK Inhibition Overcomes Cisplatin Resistance Conferred by SOS/MAPK Pathway Activation in Squamous Cell Carcinoma Open
Cisplatin resistance in head and neck squamous cell carcinoma (HNSCC) cells is associated with activation of MAPK/ERK pathway.
View article: Supplementary Figure S4 from Preclinical Evaluation of Transcriptional Targeting Strategy for Human Hepatocellular Carcinoma in an Orthotopic Xenograft Mouse Model
Supplementary Figure S4 from Preclinical Evaluation of Transcriptional Targeting Strategy for Human Hepatocellular Carcinoma in an Orthotopic Xenograft Mouse Model Open
Supplementary Figure S4 - PDF file 160K, Immunohistochemistry analysis on primary HCC and RCC tumor sections. A, Primary HCC 26-1004 and B, primary RCC 09-1210C. Tumor sections were stained with antibodies against human fibroblast, human n…
View article: Supplementary Figure S8 from MEK Inhibition Overcomes Cisplatin Resistance Conferred by SOS/MAPK Pathway Activation in Squamous Cell Carcinoma
Supplementary Figure S8 from MEK Inhibition Overcomes Cisplatin Resistance Conferred by SOS/MAPK Pathway Activation in Squamous Cell Carcinoma Open
MEK inhibition enhances colony inhibition in lung squamous cell carcinoma (SCC) cells.
View article: Supplementary Figure S7 from MEK Inhibition Overcomes Cisplatin Resistance Conferred by SOS/MAPK Pathway Activation in Squamous Cell Carcinoma
Supplementary Figure S7 from MEK Inhibition Overcomes Cisplatin Resistance Conferred by SOS/MAPK Pathway Activation in Squamous Cell Carcinoma Open
Effects of EGFR/RAF/MEK inhibitors on MAPK/ERK pathway in squamous cell carcinoma (SCC) cells.
View article: Supplementary Figure and Table Legends from FGFR-Mediated Reactivation of MAPK Signaling Attenuates Antitumor Effects of Imatinib in Gastrointestinal Stromal Tumors
Supplementary Figure and Table Legends from FGFR-Mediated Reactivation of MAPK Signaling Attenuates Antitumor Effects of Imatinib in Gastrointestinal Stromal Tumors Open
Supplementary Figure and Table Legends
View article: Supplementary Figure S7 from Preclinical Evaluation of Transcriptional Targeting Strategy for Human Hepatocellular Carcinoma in an Orthotopic Xenograft Mouse Model
Supplementary Figure S7 from Preclinical Evaluation of Transcriptional Targeting Strategy for Human Hepatocellular Carcinoma in an Orthotopic Xenograft Mouse Model Open
Supplementary Figure S7 - PDF file 643K, Chemical structure of DZNep (3-Deazaneplanocin A). Adapted from Sigma-Aldrich (catalog number SML0305)
View article: Supplementary Figure S2 from Preclinical Evaluation of Transcriptional Targeting Strategy for Human Hepatocellular Carcinoma in an Orthotopic Xenograft Mouse Model
Supplementary Figure S2 from Preclinical Evaluation of Transcriptional Targeting Strategy for Human Hepatocellular Carcinoma in an Orthotopic Xenograft Mouse Model Open
Supplementary Figure S2 - PDF file 104K, Cell cycle-dependent gene expression of AH-6CC-L2C in proliferating orthotopic PLC/PRF/5-DsRed2 tumors versus non-proliferating quiescent normal liver cells in SCID mice. A, Cell cycle analysis of p…
View article: Supplementary Figure S4 from Preclinical Evaluation of Transcriptional Targeting Strategy for Human Hepatocellular Carcinoma in an Orthotopic Xenograft Mouse Model
Supplementary Figure S4 from Preclinical Evaluation of Transcriptional Targeting Strategy for Human Hepatocellular Carcinoma in an Orthotopic Xenograft Mouse Model Open
Supplementary Figure S4 - PDF file 160K, Immunohistochemistry analysis on primary HCC and RCC tumor sections. A, Primary HCC 26-1004 and B, primary RCC 09-1210C. Tumor sections were stained with antibodies against human fibroblast, human n…
View article: Supplementary Figure S2 from Preclinical Evaluation of Transcriptional Targeting Strategy for Human Hepatocellular Carcinoma in an Orthotopic Xenograft Mouse Model
Supplementary Figure S2 from Preclinical Evaluation of Transcriptional Targeting Strategy for Human Hepatocellular Carcinoma in an Orthotopic Xenograft Mouse Model Open
Supplementary Figure S2 - PDF file 104K, Cell cycle-dependent gene expression of AH-6CC-L2C in proliferating orthotopic PLC/PRF/5-DsRed2 tumors versus non-proliferating quiescent normal liver cells in SCID mice. A, Cell cycle analysis of p…
View article: Supplementary Figure S11 from MEK Inhibition Overcomes Cisplatin Resistance Conferred by SOS/MAPK Pathway Activation in Squamous Cell Carcinoma
Supplementary Figure S11 from MEK Inhibition Overcomes Cisplatin Resistance Conferred by SOS/MAPK Pathway Activation in Squamous Cell Carcinoma Open
MEK inhibition triggers G1 arrest, while cisplatin induced S-phase arrest, in lung SCC cells.
View article: Supplementary Figure S8 from MEK Inhibition Overcomes Cisplatin Resistance Conferred by SOS/MAPK Pathway Activation in Squamous Cell Carcinoma
Supplementary Figure S8 from MEK Inhibition Overcomes Cisplatin Resistance Conferred by SOS/MAPK Pathway Activation in Squamous Cell Carcinoma Open
MEK inhibition enhances colony inhibition in lung squamous cell carcinoma (SCC) cells.
View article: Supplementary Figure S11 from MEK Inhibition Overcomes Cisplatin Resistance Conferred by SOS/MAPK Pathway Activation in Squamous Cell Carcinoma
Supplementary Figure S11 from MEK Inhibition Overcomes Cisplatin Resistance Conferred by SOS/MAPK Pathway Activation in Squamous Cell Carcinoma Open
MEK inhibition triggers G1 arrest, while cisplatin induced S-phase arrest, in lung SCC cells.
View article: Data from FGFR-Mediated Reactivation of MAPK Signaling Attenuates Antitumor Effects of Imatinib in Gastrointestinal Stromal Tumors
Data from FGFR-Mediated Reactivation of MAPK Signaling Attenuates Antitumor Effects of Imatinib in Gastrointestinal Stromal Tumors Open
Activating mutations in either KIT or PDGFRA are present in approximately 90% of gastrointestinal stromal tumors (GIST). Although treatment with the KIT and PDGFR inhibitor imatinib can control advanced disease in about 80% of GIST patient…
View article: Supplementary Text from MEK Inhibition Overcomes Cisplatin Resistance Conferred by SOS/MAPK Pathway Activation in Squamous Cell Carcinoma
Supplementary Text from MEK Inhibition Overcomes Cisplatin Resistance Conferred by SOS/MAPK Pathway Activation in Squamous Cell Carcinoma Open
Supplementary Methods Supplementary Table Captions and legends for Supplementary Figures S1 -S11; Supplementary Table S1: Differentially regulated genes in both cisplatin-resistant and -sensitive phenotypes after cisplatin treatment (fold …
View article: Supplementary Figure Legends from Preclinical Evaluation of Transcriptional Targeting Strategy for Human Hepatocellular Carcinoma in an Orthotopic Xenograft Mouse Model
Supplementary Figure Legends from Preclinical Evaluation of Transcriptional Targeting Strategy for Human Hepatocellular Carcinoma in an Orthotopic Xenograft Mouse Model Open
Supplementary Figure Legends - PDF file 83K, Supplementary Figure legends for Figure S1, S2, S3, S4, S5, S6, S7 and S8
View article: Supplementary Figure 2 from Loss of Tuberous Sclerosis Complex 2 (TSC2) Is Frequent in Hepatocellular Carcinoma and Predicts Response to mTORC1 Inhibitor Everolimus
Supplementary Figure 2 from Loss of Tuberous Sclerosis Complex 2 (TSC2) Is Frequent in Hepatocellular Carcinoma and Predicts Response to mTORC1 Inhibitor Everolimus Open
Mechanisms of TSC2 loss in HCC cell lines and xenografts. (A) Taqman RT-PCR analysis of TSC1 and TSC2 mRNA levels in HCC cell lines. (B) Taqman RT-PCR analysis of MZB1, TSC1 and TSC2 mRNA levels in TSC2-null Li-7 cells treated with epigene…
View article: Supplementary Figure S3 from MEK Inhibition Overcomes Cisplatin Resistance Conferred by SOS/MAPK Pathway Activation in Squamous Cell Carcinoma
Supplementary Figure S3 from MEK Inhibition Overcomes Cisplatin Resistance Conferred by SOS/MAPK Pathway Activation in Squamous Cell Carcinoma Open
Effects of cisplatin treatment on levels of phosphorylated kinases are assessed in H596 and Calu-1 cells.
View article: Supplementary Table S2 from FGFR-Mediated Reactivation of MAPK Signaling Attenuates Antitumor Effects of Imatinib in Gastrointestinal Stromal Tumors
Supplementary Table S2 from FGFR-Mediated Reactivation of MAPK Signaling Attenuates Antitumor Effects of Imatinib in Gastrointestinal Stromal Tumors Open
Annotation of cell lines.
View article: Supplementary Table S1 from FGFR-Mediated Reactivation of MAPK Signaling Attenuates Antitumor Effects of Imatinib in Gastrointestinal Stromal Tumors
Supplementary Table S1 from FGFR-Mediated Reactivation of MAPK Signaling Attenuates Antitumor Effects of Imatinib in Gastrointestinal Stromal Tumors Open
Annotation of primary tumor tissues.
View article: Supplementary Table S3 from FGFR-Mediated Reactivation of MAPK Signaling Attenuates Antitumor Effects of Imatinib in Gastrointestinal Stromal Tumors
Supplementary Table S3 from FGFR-Mediated Reactivation of MAPK Signaling Attenuates Antitumor Effects of Imatinib in Gastrointestinal Stromal Tumors Open
Differentially expressed genes (DEGs) identified from RNA-Seq by DeSeq between control and imatinib-treated GIST cell lines.