Hunki Kwon
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View article: Self‐Reinforcing Degradation of Solution‐Processed Small‐Molecule OLEDs: Excited‐States and Molecular Interactions as Key Triggers
Self‐Reinforcing Degradation of Solution‐Processed Small‐Molecule OLEDs: Excited‐States and Molecular Interactions as Key Triggers Open
Solution‐processed organic light‐emitting diodes (SOLEDs) are promising candidates for cost‐efficient and scalable displays, if their operational stability can be increased to match that of thermal‐evaporation‐processed OLEDs. This study p…
View article: Medication versus globus pallidus internus deep brain stimulation in Parkinson’s disease with deep learning video analysis of finger tapping
Medication versus globus pallidus internus deep brain stimulation in Parkinson’s disease with deep learning video analysis of finger tapping Open
In advanced Parkinson's disease (PD), considerable number of patients receive deep brain stimulation (DBS) surgery, to alleviate symptoms not readily controlled by medication. However, the differential effects of medication and DBS on impr…
View article: Changes in slow oscillations and sleep spindles by auditory stimulation positively correlate with memory consolidation in children with epilepsy and controls
Changes in slow oscillations and sleep spindles by auditory stimulation positively correlate with memory consolidation in children with epilepsy and controls Open
Background Sleep-dependent memory consolidation is supported by sleep spindles during stages 2 and 3 non-rapid eye movement sleep. Sleep spindles and sleep-dependent memory consolidation are both decreased in Rolandic epilepsy (RE). Non-in…
View article: A hierarchical cascade of sleep rhythms drive memory consolidation in humans and are disrupted in epilepsy
A hierarchical cascade of sleep rhythms drive memory consolidation in humans and are disrupted in epilepsy Open
The cross-regional interplay of slow oscillations, sleep spindles, and ripples during sleep is believed to support systems memory consolidation but is understudied in humans. Using a validated behavioral task and intracranial neural record…
View article: The neural activity of auditory conscious perception
The neural activity of auditory conscious perception Open
Although recent work has made headway in understanding the neural temporospatial dynamics of conscious perception, much of that work has focused on visual paradigms. To determine whether there are shared mechanisms for perceptual conscious…
View article: Impaired sleep-dependent memory consolidation predicted by reduced sleep spindles in Rolandic epilepsy
Impaired sleep-dependent memory consolidation predicted by reduced sleep spindles in Rolandic epilepsy Open
Background and Objectives Sleep spindles are prominent thalamocortical brain oscillations during sleep that have been mechanistically linked to sleep-dependent memory consolidation in animal models and healthy controls. Sleep spindles are …
View article: Preliminary evidence of a relationship between sleep spindles and treatment response in epileptic encephalopathy
Preliminary evidence of a relationship between sleep spindles and treatment response in epileptic encephalopathy Open
Objective Epileptic encephalopathy with spike‐wave activation in sleep (EE‐SWAS) is a challenging neurodevelopmental disease characterized by abundant epileptiform spikes during non‐rapid eye movement (NREM) sleep accompanied by cognitive …
View article: Decreased thalamocortical connectivity in resolved Rolandic epilepsy
Decreased thalamocortical connectivity in resolved Rolandic epilepsy Open
View article: Preliminary evidence of a relationship between sleep spindles and treatment response in epileptic encephalopathy
Preliminary evidence of a relationship between sleep spindles and treatment response in epileptic encephalopathy Open
Objective Epileptic encephalopathy with spike wave activation in sleep (EE-SWAS) is a challenging neurodevelopmental disease characterized by abundant epileptiform spikes during non-rapid eye movement (NREM) sleep accompanied by cognitive …
View article: Sleep spindles in the healthy brain from birth through 18 years
Sleep spindles in the healthy brain from birth through 18 years Open
Study Objective Sleep spindles are present from birth and reflect cognitive functions across the lifespan, but normative values for this cognitive biomarker across development are lacking. This study aims to establish normative spindle fea…
View article: The neural activity of auditory conscious perception
The neural activity of auditory conscious perception Open
Although recent work has made significant headway in understanding the temporal and spatial dynamics of the neural mechanisms of conscious perception, much of that work has focused on visual paradigms. To determine whether there are shared…
View article: Human visual consciousness involves large scale cortical and subcortical networks independent of task report and eye movement activity
Human visual consciousness involves large scale cortical and subcortical networks independent of task report and eye movement activity Open
The full neural circuits of conscious perception remain unknown. Using a visual perception task, we directly recorded a subcortical thalamic awareness potential (TAP). We also developed a unique paradigm to classify perceived versus not pe…
View article: Normative sleep spindle database and findings from 772 healthy children from birth through 18 years
Normative sleep spindle database and findings from 772 healthy children from birth through 18 years Open
Work in the last two decades has identified sleep spindles, discrete “sigma band” oscillations during stage 2 sleep, as a key oscillatory mechanism required for off-line memory consolidation. Although, sleep spindles are known to evolve co…
View article: Transient, developmental functional and structural connectivity abnormalities in the thalamocortical motor network in Rolandic epilepsy
Transient, developmental functional and structural connectivity abnormalities in the thalamocortical motor network in Rolandic epilepsy Open
View article: Early neural activity changes associated with visual conscious perception
Early neural activity changes associated with visual conscious perception Open
The neural mechanisms of visual conscious perception have been investigated for decades. However, the spatiotemporal dynamics associated with the earliest neural responses following consciously perceived stimuli are still poorly understood…
View article: The major brain networks of human visual consciousness
The major brain networks of human visual consciousness Open
Understanding consciousness is one of the most important and challenging questions in modern science. Existing theories have pursued single unifying mechanisms but do not succeed in explaining consciousness. Importantly, the neural circuit…
View article: Brain networks in human conscious visual perception
Brain networks in human conscious visual perception Open
Consciousness is not explained by a single mechanism, rather it involves multiple specialized neural systems overlapping in space and time. We hypothesize that synergistic, large-scale subcortical and cortical attention and signal processi…
View article: Early cortical signals in visual stimulus detection
Early cortical signals in visual stimulus detection Open
View article: Diazepam induced sleep spindle increase correlates with cognitive recovery in a child with epileptic encephalopathy
Diazepam induced sleep spindle increase correlates with cognitive recovery in a child with epileptic encephalopathy Open
Background Continuous spike and wave of sleep with encephalopathy (CSWS) is a rare and severe developmental electroclinical epileptic encephalopathy characterized by seizures, abundant sleep activated interictal epileptiform discharges, an…
View article: White Matter Integrity Is Associated With the Amount of Physical Activity in Older Adults With Super-aging
White Matter Integrity Is Associated With the Amount of Physical Activity in Older Adults With Super-aging Open
Previous studies have introduced the concept of "SuperAgers," defined as older adults with youthful memory performance associated with the increased cortical thickness of the anterior cingulate cortex. Given that age-related structural bra…
View article: Urate is closely linked to white matter integrity in multiple system atrophy
Urate is closely linked to white matter integrity in multiple system atrophy Open
Objective We aimed to investigate the association of the serum urate level with cortical thickness and white matter integrity in multiple system atrophy (MSA). Methods We recruited 75 MSA patients and 42 controls who underwent brain MRI an…
View article: Author Correction: Multimodal imaging analyses in patients with genetic and sporadic forms of small vessel disease
Author Correction: Multimodal imaging analyses in patients with genetic and sporadic forms of small vessel disease Open
View article: Default mode and visual network activity in an attention task: Direct measurement with intracranial EEG
Default mode and visual network activity in an attention task: Direct measurement with intracranial EEG Open
View article: Frontal atrophy as a marker for dementia conversion in Parkinson's disease with mild cognitive impairment
Frontal atrophy as a marker for dementia conversion in Parkinson's disease with mild cognitive impairment Open
This study aimed to investigate the cortical neural correlates of dementia conversion in Parkinson's disease with mild cognitive impairment (PD‐MCI). We classified 112 patients with drug‐naïve early stage PD meeting criteria for PD‐MCI int…
View article: A Physarum Centrality Measure of the Human Brain Network
A Physarum Centrality Measure of the Human Brain Network Open
The most important goals of brain network analyses are to (a) detect pivotal regions and connections that contribute to disproportionate communication flow, (b) integrate global information, and (c) increase the brain network efficiency. M…
View article: Brain structural changes after multi‐strategic metamemory training in older adults with subjective memory complaints: A randomized controlled trial
Brain structural changes after multi‐strategic metamemory training in older adults with subjective memory complaints: A randomized controlled trial Open
Background Metamemory is the process of monitoring and controlling one's memory. Improving metamemory may reduce the memory problem in old age. We hypothesized that metamemory training (MMT) would improve cognition in older adults with sub…
View article: Multimodal imaging analyses in patients with genetic and sporadic forms of small vessel disease
Multimodal imaging analyses in patients with genetic and sporadic forms of small vessel disease Open
Cerebral autosomal dominant arteriopathy with subcortical infarcts and leukoencephalopathy (CADASIL) is thought to be a pure genetic form of subcortical vascular cognitive impairment (SVCI). The aim of this study was to compare white matte…
View article: Clinical relevance of amnestic versus non‐amnestic mild cognitive impairment subtyping in Parkinson's disease
Clinical relevance of amnestic versus non‐amnestic mild cognitive impairment subtyping in Parkinson's disease Open
Background and purpose To clarify whether subtyping of amnestic and non‐amnestic mild cognitive impairment ( MCI ) is clinically relevant in Parkinson's disease ( PD ) by analyzing patterns of neuroimaging and longitudinal cognitive change…
View article: Neural predictors of cognitive improvement by multi-strategic memory training based on metamemory in older adults with subjective memory complaints
Neural predictors of cognitive improvement by multi-strategic memory training based on metamemory in older adults with subjective memory complaints Open
View article: Evaluation of Cerebral White Matter in Prelingually Deaf Children Using Diffusion Tensor Imaging
Evaluation of Cerebral White Matter in Prelingually Deaf Children Using Diffusion Tensor Imaging Open
This study compared white matter development in prelingually deaf and normal-hearing children using a tract-based spatial statistics (TBSS) method. Diffusion tensor imaging (DTI) was performed in 21 prelingually deaf (DEAF group) and 20 no…