Hunter B. Moore
YOU?
Author Swipe
View article: TEG® 6s Heparin Neutralization Cartridge for Hemostatic Assessment of Patients Undergoing Cardiovascular Surgery
TEG® 6s Heparin Neutralization Cartridge for Hemostatic Assessment of Patients Undergoing Cardiovascular Surgery Open
Background: Heparin administration can limit viscoelastic testing. The cartridge-based TEG ® 6s thromboelastography system (Haemonetics Corp., USA) uses heparinase to neutralize heparin effects. This study aimed to validate the TEG 6s glob…
View article: Magnetic resonance imaging in patients with cardiac implanted electronic devices: impact of an automatic MRI programming function on patient wait times and outcomes
Magnetic resonance imaging in patients with cardiac implanted electronic devices: impact of an automatic MRI programming function on patient wait times and outcomes Open
Background/Introduction Performing magnetic resonance (MRI) scans in patients with cardiac implanted electronic devices (CIEDs) is logistically challenging as pre- and post- MRI device programming to ensure an ‘MRI safe’ mode (usually ‘DOO…
View article: Erratum to ‘Illustrated State-of-the-Art Capsules of the ISTH 2024 Congress’ [Research and Practice in Thrombosis and Haemostasis Volume 8, Issue 4, May 2024, 102432]
Erratum to ‘Illustrated State-of-the-Art Capsules of the ISTH 2024 Congress’ [Research and Practice in Thrombosis and Haemostasis Volume 8, Issue 4, May 2024, 102432] Open
[This corrects the article DOI: 10.1016/j.rpth.2024.102432.].
View article: Fibrinolysis Resistance After Injury Is a Risk Factor for a Hospital-Acquired Pneumonia-Like Disease Pattern
Fibrinolysis Resistance After Injury Is a Risk Factor for a Hospital-Acquired Pneumonia-Like Disease Pattern Open
Background: Pneumonia is associated with increased morbidity and costs in the intensive care unit (ICU). Its early identification is key for optimal outcomes, but early biomarkers are lacking. Studies suggest that fibrinolysis resistance (…
View article: Corrigendum: Iatrogenic air embolism: pathoanatomy, thromboinflammation, endotheliopathy, and therapies
Corrigendum: Iatrogenic air embolism: pathoanatomy, thromboinflammation, endotheliopathy, and therapies Open
[This corrects the article DOI: 10.3389/fimmu.2023.1230049.].
View article: Versatile, in-line optical oxygen tension sensors for continuous monitoring during <i>ex vivo</i> kidney perfusion
Versatile, in-line optical oxygen tension sensors for continuous monitoring during <i>ex vivo</i> kidney perfusion Open
We report an optical oxygenation sensor technology comprising flow cell elements paired with electronic readout devices. Successful implementation in inflow and outflow oxygenation monitoring during ex vivo kidney perfusion is demonstrated.
View article: Combination of aspirin and rosuvastatin for reduction of venous thromboembolism in severely injured patients: a double-blind, placebo-controlled, pragmatic randomized phase II clinical trial (The STAT Trial)
Combination of aspirin and rosuvastatin for reduction of venous thromboembolism in severely injured patients: a double-blind, placebo-controlled, pragmatic randomized phase II clinical trial (The STAT Trial) Open
Introduction Venous thromboembolism (VTE) remains a significant source of postinjury morbidity and mortality. Beta-hydroxy beta-methylglutaryl-CoA (HMG-CoA) reductase inhibitors (rosuvastatin) significantly reduced pathologic clotting even…
View article: OC 53.2 Does Plasminogen Replenishment Correct Recovery from Fibrinolysis Resistance Following Liver Transplantation?
OC 53.2 Does Plasminogen Replenishment Correct Recovery from Fibrinolysis Resistance Following Liver Transplantation? Open
age matched healthy controls who experienced no adverse effects following vaccination.All patients received the Astra-Zeneca vaccine.Methods: Levels of plasmin-antiplasmin (PAP) complexes, plasminogen, and alpha2-anti-plasmin in citrated p…
View article: Iatrogenic air embolism: pathoanatomy, thromboinflammation, endotheliopathy, and therapies
Iatrogenic air embolism: pathoanatomy, thromboinflammation, endotheliopathy, and therapies Open
Iatrogenic vascular air embolism is a relatively infrequent event but is associated with significant morbidity and mortality. These emboli can arise in many clinical settings such as neurosurgery, cardiac surgery, and liver transplantation…
View article: Development and in-vivo validation of a portable phosphorescence lifetime-based fiber-optic oxygen sensor
Development and in-vivo validation of a portable phosphorescence lifetime-based fiber-optic oxygen sensor Open
Oxygenation is a crucial indicator of tissue viability and function. Oxygen tension ( $$\hbox {pO}_2$$ ), i.e. the amount of molecular oxygen present in the tissue is a direct result of supply (perfusion) and consumption. Thus, measure…
View article: Serial “death diamond” TEGs are a bedside indicator of futile resuscitation during massive transfusion
Serial “death diamond” TEGs are a bedside indicator of futile resuscitation during massive transfusion Open
Serial DDs could serve as rapid check points to gauge the likelihood of success of continued resuscitation. Loudon et al.’s work combined with the use of serial DDs may serve as building blocks toward a trial using VETs to predict continue…
View article: SHock-INduced Endotheliopathy (SHINE): A mechanistic justification for viscoelastography-guided resuscitation of traumatic and non-traumatic shock
SHock-INduced Endotheliopathy (SHINE): A mechanistic justification for viscoelastography-guided resuscitation of traumatic and non-traumatic shock Open
Irrespective of the reason for hypoperfusion, hypocoagulable and/or hyperfibrinolytic hemostatic aberrancies afflict up to one-quarter of critically ill patients in shock. Intensivists and traumatologists have embraced the concept of SHock…
View article: A proposed clinical coagulation score for research in trauma-induced coagulopathy
A proposed clinical coagulation score for research in trauma-induced coagulopathy Open
BACKGROUND Trauma-induced coagulopathy (TIC) has been the subject of intense study for greater than a century, and it is associated with high morbidity and mortality. The Trans-Agency Consortium for Trauma-Induced Coagulopathy, funded by t…
View article: Postoperative fibrinolytic resistance is associated with early allograft dysfunction in liver transplantation: A prospective observational study
Postoperative fibrinolytic resistance is associated with early allograft dysfunction in liver transplantation: A prospective observational study Open
Perioperative dysfunction of the fibrinolytic system may play a role in adverse outcomes for liver transplant recipients. There is a paucity of data describing the potential impact of the postoperative fibrinolytic system on these outcomes…
View article: Reply to Bareille et al. Are Viscoelastometric Assays of Old Generation Ready for Disposal? Comment on “Volod et al. Viscoelastic Hemostatic Assays: A Primer on Legacy and New Generation Devices. J. Clin. Med. 2022, 11, 860”
Reply to Bareille et al. Are Viscoelastometric Assays of Old Generation Ready for Disposal? Comment on “Volod et al. Viscoelastic Hemostatic Assays: A Primer on Legacy and New Generation Devices. J. Clin. Med. 2022, 11, 860” Open
We are pleased to see that Bareille et al. have written a Commentary: “Are viscoelastometric assays of old generation ready for disposal?” [...]
View article: Can <scp>non‐directed</scp> living liver donation help improve access to grafts and correct socioeconomic disparities in pediatric liver transplantation?
Can <span>non‐directed</span> living liver donation help improve access to grafts and correct socioeconomic disparities in pediatric liver transplantation? Open
Background Each year, children die awaiting LT as the demand for grafts exceeds the available supply. Candidates with public health insurance are significantly less likely to undergo both deceased donor LT and D‐LLD LT. ND‐LLD is another o…
View article: Viscoelastic Management of Coagulopathy during the Perioperative Period of Liver Transplantation
Viscoelastic Management of Coagulopathy during the Perioperative Period of Liver Transplantation Open
Viscoelastic testing (VET) in liver transplantation (LT) has been used since its origin, in combination with standard laboratory testing (SLT). There are only a few, small, randomized controlled trials that demonstrated a reduction in tran…
View article: Fibrinolysis Shutdown and Hypofibrinolysis Are Not Synonymous Terms: The Clinical Significance of Differentiating Low Fibrinolytic States
Fibrinolysis Shutdown and Hypofibrinolysis Are Not Synonymous Terms: The Clinical Significance of Differentiating Low Fibrinolytic States Open
Low fibrinolytic activity has been associated with pathologic thrombosis and multiple-organ failure. Low fibrinolytic activity has two commonly associated terms, hypofibrinolysis and fibrinolysis shutdown. Hypofibrinolysis is a chronic sta…
View article: Relative Hypercoagulopathy of the SARS-CoV-2 Beta and Delta Variants when Compared to the Less Severe Omicron Variants Is Related to TEG Parameters, the Extent of Fibrin Amyloid Microclots, and the Severity of Clinical Illness
Relative Hypercoagulopathy of the SARS-CoV-2 Beta and Delta Variants when Compared to the Less Severe Omicron Variants Is Related to TEG Parameters, the Extent of Fibrin Amyloid Microclots, and the Severity of Clinical Illness Open
Earlier variants of SARS-CoV-2 have been associated with hypercoagulability and an extensive formation of fibrin amyloid microclots, which are considered to contribute to the pathology of the coronavirus 2019 disease (COVID-19). The newer …
View article: Resuscitative Endovascular Balloon Occlusion of the Aorta as a Bridge to Organ Donation after Blunt Trauma
Resuscitative Endovascular Balloon Occlusion of the Aorta as a Bridge to Organ Donation after Blunt Trauma Open
Solid organ transplantation is limited worldwide by a shortage of donor organs. Trauma patients with unsurvivable injuries comprise a large portion of potential organ donors, but many of them die from cardiovascular collapse before donatio…