Huoming Zhang
YOU?
Author Swipe
View article: Optimized Time-Segmented Acquisition Expands Peptide and Protein Identification in TIMS-TOF Pro Mass Spectrometry
Optimized Time-Segmented Acquisition Expands Peptide and Protein Identification in TIMS-TOF Pro Mass Spectrometry Open
We introduce here a novel approach, termed time-segmented acquisition (Seg), to enhance the identification of peptides and proteins in trapped ion mobility spectrometry (TIMS)-time-of-flight (TOF) mass spectrometry. Our method exploits the…
View article: Author Correction: LINE-1 RNA triggers matrix formation in bone cells via a PKR-mediated inflammatory response
Author Correction: LINE-1 RNA triggers matrix formation in bone cells via a PKR-mediated inflammatory response Open
[Image: see text]
View article: LINE-1 RNA triggers matrix formation in bone cells via a PKR-mediated inflammatory response
LINE-1 RNA triggers matrix formation in bone cells via a PKR-mediated inflammatory response Open
View article: Optimized Time-segmented Acquisition Expands Peptide and Protein Identification in TIMS-TOF Pro Mass Spectrometry
Optimized Time-segmented Acquisition Expands Peptide and Protein Identification in TIMS-TOF Pro Mass Spectrometry Open
We introduce here a novel approach, termed time-segmented acquisition (Seg), to enhance the identification of peptides and proteins in trapped ion mobility spectrometry (TIMS)-Time of flight (TOF) mass spectrometry. Our method exploits the…
View article: Impact of the SARS-CoV-2 nucleocapsid 203K/204R mutations on the inflammatory immune response in COVID-19 severity
Impact of the SARS-CoV-2 nucleocapsid 203K/204R mutations on the inflammatory immune response in COVID-19 severity Open
Background The excessive inflammatory responses provoked by SARS-CoV-2 infection are critical factors affecting the severity and mortality of COVID-19. Previous work found that two adjacent co-occurring mutations R203K and G204R (KR) on th…
View article: Additional file 2 of Impact of the SARS-CoV-2 nucleocapsid 203K/204R mutations on the inflammatory immune response in COVID-19 severity
Additional file 2 of Impact of the SARS-CoV-2 nucleocapsid 203K/204R mutations on the inflammatory immune response in COVID-19 severity Open
Additional file 2: Table S1. Demorgraphic and clinical information of all samples. Table S2. All significant DE genes (KR-patients versus Healthy). Table S3. All significant DE genes (RG-patients versus Healthy). Table S4. All DE genes (KR…
View article: Analysis of the Arabidopsis<i>coilin</i>mutant reveals a positive role of AtCOILIN in plant immunity
Analysis of the Arabidopsis<i>coilin</i>mutant reveals a positive role of AtCOILIN in plant immunity Open
Biogenesis of ribonucleoproteins occurs in dynamic subnuclear compartments called Cajal bodies (CBs). COILIN is a critical scaffolding component essential for CB formation, composition, and activity. We recently showed that Arabidopsis (Ar…
View article: SARS-CoV-2 genomes from Saudi Arabia implicate nucleocapsid mutations in host response and increased viral load
SARS-CoV-2 genomes from Saudi Arabia implicate nucleocapsid mutations in host response and increased viral load Open
View article: Narrow Precursor Mass Range for DIA–MS Enhances Protein Identification and Quantification in Arabidopsis
Narrow Precursor Mass Range for DIA–MS Enhances Protein Identification and Quantification in Arabidopsis Open
Data independent acquisition–mass spectrometry (DIA–MS) is becoming widely utilised for robust and accurate quantification of samples in quantitative proteomics. Here, we describe the systematic evaluation of the effects of DIA precursor m…
View article: Narrow Precursor Mass Range for DIA-MS Enhances Protein Identification and Quantification
Narrow Precursor Mass Range for DIA-MS Enhances Protein Identification and Quantification Open
Data independent acquisition - mass spectrometry (DIA-MS) is becoming widely utilised for robust and accurate quantification of samples in quantitative proteomics. Here, we describe the systematic evaluation of the effects of DIA precursor…
View article: Saudi Arabian SARS-CoV-2 genomes implicate a mutant Nucleocapsid protein in modulating host interactions and increased viral load in COVID-19 patients
Saudi Arabian SARS-CoV-2 genomes implicate a mutant Nucleocapsid protein in modulating host interactions and increased viral load in COVID-19 patients Open
Summary Monitoring SARS-CoV-2 spread and evolution through genome sequencing is essential in handling the COVID-19 pandemic. The availability of patient hospital records is crucial for linking the genomic sequence information to virus func…
View article: Author Correction: Arabidopsis proteome and the mass spectral assay library
Author Correction: Arabidopsis proteome and the mass spectral assay library Open
View article: Celecoxib Exerts a Therapeutic Effect Against Demyelination by Improving the Immune and Inflammatory Microenvironments
Celecoxib Exerts a Therapeutic Effect Against Demyelination by Improving the Immune and Inflammatory Microenvironments Open
Peipei Cao,1 Hao Zhang,2 Huiling Meng,1 Yajia Cheng,1 Haiqi Xu,3 Siwen Zang,1 Zongjin Li,1 Jianlin Cui,1,4 Yuhao Li1,5 1Nankai University School of Medicine, Tianjin, People’s Republic of China; 2Department of Neurosurgery, Tianjin Medical…
View article: Probing SWATH‐MS as a tool for proteome level quantification in a nonmodel fish
Probing SWATH‐MS as a tool for proteome level quantification in a nonmodel fish Open
Quantitative proteomics via mass spectrometry can provide valuable insight into molecular and phenotypic characteristics of a living system. Recent mass spectrometry developments include data‐independent acquisition (SWATH/DIA‐MS), an accu…
View article: Probing SWATH-MS as a tool for proteome level quantification in a non-model fish
Probing SWATH-MS as a tool for proteome level quantification in a non-model fish Open
Quantitative proteomics via mass spectrometry can provide valuable insight into molecular and phenotypic characteristics of a living system. Recent mass spectrometry developments include data-independent acquisition (SWATH/DIA-MS), an accu…
View article: Metadata record for: Arabidopsis proteome and the mass spectral assay library
Metadata record for: Arabidopsis proteome and the mass spectral assay library Open
This dataset contains key characteristics about the data described in the Data Descriptor Arabidopsis proteome and the mass spectral assay library. Contents: 1. human readable metadata summary table in CSV format 2. machine readable meta…
View article: Ubiquitin ligases HUWE1 and NEDD4 cooperatively control signal-dependent PRC2-Ezh1α/β-mediated adaptive stress response pathway in skeletal muscle cells
Ubiquitin ligases HUWE1 and NEDD4 cooperatively control signal-dependent PRC2-Ezh1α/β-mediated adaptive stress response pathway in skeletal muscle cells Open
View article: Arabidopsis proteome and the mass spectral assay library
Arabidopsis proteome and the mass spectral assay library Open
View article: Evidence for a role of protein phosphorylation in the maintenance of the cnidarian–algal symbiosis
Evidence for a role of protein phosphorylation in the maintenance of the cnidarian–algal symbiosis Open
The endosymbiotic relationship between cnidarians and photosynthetic dinoflagellate algae provides the foundation of coral reef ecosystems. This essential interaction is globally threatened by anthropogenic disturbance. As such, it is impo…
View article: Research on K nearest neighbor identification of hand-drawn circuit diagram
Research on K nearest neighbor identification of hand-drawn circuit diagram Open
Aiming at the problem of accurately identifying each hand-painted electrical component in the hand-drawn circuit diagram, this paper proposes a region segmentation based on pixel number distribution, and a hand-painted electrical component…
View article: <scp>MAP</scp> 4K4 associates with <scp>BIK</scp> 1 to regulate plant innate immunity
<span>MAP</span> 4K4 associates with <span>BIK</span> 1 to regulate plant innate immunity Open
View article: Arabidopsis Proteome and the Mass Spectral Assay Library
Arabidopsis Proteome and the Mass Spectral Assay Library Open
Arabidopsis is an important model organism and the first plant with its genome sequenced. Knowledge from studying this species has either direct or indirect applications to agriculture and human health. Quantitative proteomics by data-inde…
View article: Integrated transcriptomic and proteomic analysis of pathogenic mycobacteria and their esx-1 mutants reveal secretion-dependent regulation of ESX-1 substrates and WhiB6 as a transcriptional regulator
Integrated transcriptomic and proteomic analysis of pathogenic mycobacteria and their esx-1 mutants reveal secretion-dependent regulation of ESX-1 substrates and WhiB6 as a transcriptional regulator Open
The mycobacterial type VII secretion system ESX-1 is responsible for the secretion of a number of proteins that play important roles during host infection. The regulation of the expression of secreted proteins is often essential to establi…
View article: Spectral library from TripleTOF 5600 instrument for inputing to Peakview Software
Spectral library from TripleTOF 5600 instrument for inputing to Peakview Software Open
Spectral library from TripleTOF 5600 instrument for inputing to Peakview Software
View article: MOESM3 of Ubiquitin ligases HUWE1 and NEDD4 cooperatively control signal-dependent PRC2-Ezh1α/β-mediated adaptive stress response pathway in skeletal muscle cells
MOESM3 of Ubiquitin ligases HUWE1 and NEDD4 cooperatively control signal-dependent PRC2-Ezh1α/β-mediated adaptive stress response pathway in skeletal muscle cells Open
Additional file 3: Datasheet 2. Protein interactome list of Ezh1 short isoform through mass spectrometry analysis under oxidative stress condition.
View article: MOESM2 of Ubiquitin ligases HUWE1 and NEDD4 cooperatively control signal-dependent PRC2-Ezh1α/β-mediated adaptive stress response pathway in skeletal muscle cells
MOESM2 of Ubiquitin ligases HUWE1 and NEDD4 cooperatively control signal-dependent PRC2-Ezh1α/β-mediated adaptive stress response pathway in skeletal muscle cells Open
Additional file 2: Datasheet 1. Mass spectrometry analysis data of low and high molecular weight band for Ezh1 short isoform.
View article: Spectral library from Fusion instrument for inputing to Peakview Software
Spectral library from Fusion instrument for inputing to Peakview Software Open
Spectral library from Fusion instrument for inputing to Peakview Software: Part 1. The size of library exceeds the Peakview loading limit, and thus it was divided into two parts.
View article: Supporting information for the novel proteins presented in Table2
Supporting information for the novel proteins presented in Table2 Open
The detailed information about the novel identification, its annotation from TAIR webpage and their matched peptides (highlighted in yellow) were presented following with this table.
View article: Metadata record for: Arabidopsis proteome and the mass spectral assay library
Metadata record for: Arabidopsis proteome and the mass spectral assay library Open
This dataset contains key characteristics about the data described in the Data Descriptor Arabidopsis proteome and the mass spectral assay library. Contents: 1. human readable metadata summary table in CSV format 2. machine readable meta…
View article: Redox Proteome Perturbation in Arabidopsis upon Pseudomonas syringae Infection
Redox Proteome Perturbation in Arabidopsis upon Pseudomonas syringae Infection Open
Oxidative burst is one of the earliest plant cellular responses triggered by pathogen infection. Reactive oxygen species can cause oxidative modifications of redox-sensitive proteins to mediate the defense responses. Identification and cha…