Hurmat Malik
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EXPLORING THE POTENTIAL PHARMACOLOGICAL EFFECT OF THYMOQUINONE IN AMELIORATING THE ACQUISITION AND EXPRESSION OF VINCRISTINE INDUCED NEUROPATHIC PAIN IN MICE Open
Background: Chemotherapy-induced neuropathy (CIPN) is the most severe consequence, causing both sensory and motor impairment with an incidence of between 19% and over 85%. Leukaemia, lymphoma, and sarcoma are just a few of the cancers that…
5,7-Dimethoxycoumarin ameliorates vincristine induced neuropathic pain: potential role of 5HT3 receptors and monoamines Open
Vincristine is the drug of choice for Hodgkin’s lymphoma, acute lymphoblastic leukemia, and non-Hodgkin lymphoma. Despite its significant anticancer effects, it causes dose-dependent neuropathy, leading to compulsive dose reduction. The av…
Diosgenin normalization of disrupted behavioral and central neurochemical activity after single prolonged stress Open
Introduction: Post-traumatic stress disorder (PTSD) is a chronic mental illness triggered by traumatic experiences such as wars, natural disasters, or catastrophes, and it is characterized by anxiety, depression and cognitive impairment. D…