Hussain Mulla
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View article: Correction: “Simultaneous Pharmacokinetic Modeling of Gentamicin, Tobramycin and Vancomycin Clearance From Neonates to Adults: Towards a Semi-physiological Function for Maturation in Glomerular Filtration”
Correction: “Simultaneous Pharmacokinetic Modeling of Gentamicin, Tobramycin and Vancomycin Clearance From Neonates to Adults: Towards a Semi-physiological Function for Maturation in Glomerular Filtration” Open
View article: The Distributions of Duffy Antigens and Phenotypes Among Blood Donors in King Abdulaziz Medical City-Western Region, Saudi Arabia: A Cross-Sectional Study
The Distributions of Duffy Antigens and Phenotypes Among Blood Donors in King Abdulaziz Medical City-Western Region, Saudi Arabia: A Cross-Sectional Study Open
The prevalence of the FY antigens and phenotypes is reported among blood donors. The Fy(a-b-) phenotype was the most widespread among Saudis and non-Saudis. It is crucial to include the FY antigens in the transfusion screening panel especi…
View article: When will the Glomerular Filtration Rate in Former Preterm Neonates Catch up with Their Term Peers?
When will the Glomerular Filtration Rate in Former Preterm Neonates Catch up with Their Term Peers? Open
View article: Efficacy, safety, and pharmacokinetics of a new, ready-to-use, liquid hydroxyurea in children with sickle cell anemia
Efficacy, safety, and pharmacokinetics of a new, ready-to-use, liquid hydroxyurea in children with sickle cell anemia Open
View article: Inflammation and cardiovascular status impact midazolam pharmacokinetics in critically ill children: An observational, prospective, controlled study
Inflammation and cardiovascular status impact midazolam pharmacokinetics in critically ill children: An observational, prospective, controlled study Open
Altered physiology caused by critical illness may change midazolam pharmacokinetics and thereby result in adverse reactions and outcomes in this vulnerable patient population. This study set out to determine which critical illness‐related …
View article: Inflammation and cardiovascular status impact midazolam pharmacokinetics in critically Ill children: an observational, prospective, controlled study
Inflammation and cardiovascular status impact midazolam pharmacokinetics in critically Ill children: an observational, prospective, controlled study Open
Aims: Altered physiology caused by critical illness may change midazolam pharmacokinetics (PK) and thereby result in adverse reactions and outcomes in this vulnerable patient population. This study set out to determine which critical illne…
View article: Infliximab: a single-centre, prospective, observational evaluation of TDM data in patients with IBD
Infliximab: a single-centre, prospective, observational evaluation of TDM data in patients with IBD Open
IFX concentrations are correlated with biomarkers, clinical response and AB development in patients with IBD. Concomitant thiopurine therapy appears to be associated with higher IFX concentrations and reduced likelihood of AB development.
View article: Pharmacokinetics and Safety of a Novel Oral Liquid Formulation of 13-cis Retinoic Acid in Children with Neuroblastoma: A Randomized Crossover Clinical Trial
Pharmacokinetics and Safety of a Novel Oral Liquid Formulation of 13-cis Retinoic Acid in Children with Neuroblastoma: A Randomized Crossover Clinical Trial Open
(1) Background: 13-cis-retinoic acid (13-CRA) is a key component of neuroblastoma treatment protocols. This randomized crossover study compares the pharmacokinetics (PK), safety and palatability of a novel oral liquid formulation to the cu…
View article: Personalised Warfarin Dosing in Children Post-cardiac Surgery
Personalised Warfarin Dosing in Children Post-cardiac Surgery Open
View article: Personalised dosing of medicines for children
Personalised dosing of medicines for children Open
Objectives Doses for most drugs are determined from population-level information, resulting in a standard ?one-size-fits-all’ dose range for all individuals. This review explores how doses can be personalised through the use of the individ…
View article: Enhanced Potency and Durability of Antibody Response to Seasonal Trivalent Inactivated Influenza Vaccine (TIV) Combined with a Novel Water-in-Oil Adjuvant System at Reduced Hemagglutinin (HA) Doses
Enhanced Potency and Durability of Antibody Response to Seasonal Trivalent Inactivated Influenza Vaccine (TIV) Combined with a Novel Water-in-Oil Adjuvant System at Reduced Hemagglutinin (HA) Doses Open
New influenza vaccines are needed to increase vaccine efficacy against infection and illness. Adjuvants may allow HA dose-sparing while increasing the antibody response. MAS-1 is an investigational low viscosity, free-flowing, water-in-oil…
View article: Population pharmacokinetics of cefazolin before, during and after cardiopulmonary bypass to optimize dosing regimens for children undergoing cardiac surgery
Population pharmacokinetics of cefazolin before, during and after cardiopulmonary bypass to optimize dosing regimens for children undergoing cardiac surgery Open
We propose an optimized dosing regimen for cefazolin during cardiac surgery in paediatric patients to avoid treatment failure due to inadequate antibiotic prophylaxis.
View article: Quantitative Analysis of Methyl and Propyl Parabens in Neonatal DBS Using LC–MS/MS
Quantitative Analysis of Methyl and Propyl Parabens in Neonatal DBS Using LC–MS/MS Open
The above assay was applied to analyze neonatal DBS samples. The blood concentrations of parabens in neonates confirm systemic exposure to parabens following administration of routine medicines.
View article: Essential medicines containing ethanol elevate blood acetaldehyde concentrations in neonates
Essential medicines containing ethanol elevate blood acetaldehyde concentrations in neonates Open
View article: High variability in the dosing of commonly used antibiotics revealed by a Europe-wide point prevalence study: implications for research and dissemination
High variability in the dosing of commonly used antibiotics revealed by a Europe-wide point prevalence study: implications for research and dissemination Open
View article: Population cefazolin pharmacokinetics before, during and after cardiopulmonary bypass in children undergoing cardiac surgery
Population cefazolin pharmacokinetics before, during and after cardiopulmonary bypass in children undergoing cardiac surgery Open