Hussain Shallwani
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View article: Cangrelor for neurointerventional procedures: A systematic review
Cangrelor for neurointerventional procedures: A systematic review Open
Thromboembolism is a complication of neurointerventional procedures that requires patients to be placed under antiplatelet therapy. Current options for antiplatelet therapies have a delayed onset of action that prevents a rapid door to pun…
View article: Novel usage of everolimus-eluting coronary stent for intracranial atherosclerotic disease: a technical report and case series
Novel usage of everolimus-eluting coronary stent for intracranial atherosclerotic disease: a technical report and case series Open
Objectives This report describes the use of an Everolimus-eluting stent (Xience Skypoint stent) for the treatment of medically-refractory ICAD. Design Retrospective, case-series Setting In-hospital patients Participants All patients in thi…
View article: Endovascular Treatment of Giant Intracranial Aneurysms
Endovascular Treatment of Giant Intracranial Aneurysms Open
Objective Giant intracranial aneurysms (GIAs) are associated with a high risk of rupture and have a high mortality rate when they rupture (65-100%). The traditional microsurgical approach to secure these lesions is challenging, and as such…
View article: Impact of Antiplatelet Therapy During Endovascular Therapy for Tandem Occlusions
Impact of Antiplatelet Therapy During Endovascular Therapy for Tandem Occlusions Open
Background and Purpose— Antiplatelet agents could be used in the setting of endovascular therapy for tandem occlusions to reduce the risk of de novo intracranial embolic migration, reocclusion of the extracranial internal carotid artery le…
View article: Submaximal Angioplasty for Symptomatic Intracranial Atherosclerotic Disease: A Meta-Analysis of Peri-Procedural and Long-Term Risk
Submaximal Angioplasty for Symptomatic Intracranial Atherosclerotic Disease: A Meta-Analysis of Peri-Procedural and Long-Term Risk Open
BACKGROUND Symptomatic intracranial atherosclerotic disease (ICAD) is an important cause of stroke. Although the high periprocedural risk of intracranial stenting from recent randomized studies has dampened enthusiasm for such intervention…
View article: High‐Definition Zoom Mode: A High Resolution X‐ray Microscope for Neurointerventional Treatment Procedures
High‐Definition Zoom Mode: A High Resolution X‐ray Microscope for Neurointerventional Treatment Procedures Open
BACKGROUND AND PURPOSE Visualization of structural details of treatment devices during neurointerventional procedures can be challenging. A new true two‐resolution imaging X‐ray detector system features a 194 µm pixel conventional flat‐pan…
View article: E-100 Predictors of unfavorable outcomes in octogenarians receiving mechanical thrombectomy for large vessel occlusion acute ischemic stroke
E-100 Predictors of unfavorable outcomes in octogenarians receiving mechanical thrombectomy for large vessel occlusion acute ischemic stroke Open
Introduction By 2050, the number of octogenarians will triple that in 2015. Currently over a third of stroke cases occur in patients aged 80 years or older. A better understanding of stroke intervention in octogenarians is warranted consid…
View article: O-005 The impact of failed reperfusion on the clincal outcomes of patients presenting with low NIHSS large vessel occlusion
O-005 The impact of failed reperfusion on the clincal outcomes of patients presenting with low NIHSS large vessel occlusion Open
Introduction The effectiveness of mechanical thrombectomy in patients presenting with a low NIHSS and large vessel occlusion is uncertain. The objective of this study was to compare clinical outcomes of patients with successful (TICI 2b/3)…
View article: Emergent Carotid Stenting Plus Thrombectomy After Thrombolysis in Tandem Strokes
Emergent Carotid Stenting Plus Thrombectomy After Thrombolysis in Tandem Strokes Open
Background and Purpose— Emergent carotid artery stenting plus mechanical thrombectomy is an effective treatment for acute ischemic stroke patients with tandem occlusion of the anterior circulation. However, there is limited data supporting…
View article: Ostium Ratio and Neck Ratio Could Predict the Outcome of Sidewall Intracranial Aneurysms Treated with Flow Diverters
Ostium Ratio and Neck Ratio Could Predict the Outcome of Sidewall Intracranial Aneurysms Treated with Flow Diverters Open
High ostium ratios and neck ratios could predict incomplete occlusion of flow diverter-treated sidewall aneurysms. Neck ratio can be easily calculated by interventionists to predict flow-diverter treatment outcomes.
View article: Transvenous embolization of thalamic arteriovenous malformation under transient cardiac standstill
Transvenous embolization of thalamic arteriovenous malformation under transient cardiac standstill Open
Transvenous embolization (TE) has been increasingly applied for arteriovenous malformation (AVM) treatment. Transient cardiac standstill (TCS) has been described in cerebrovascular surgery but is uncommon for endovascular embolization. The…
View article: Biomarkers from circulating neutrophil transcriptomes have potential to detect unruptured intracranial aneurysms
Biomarkers from circulating neutrophil transcriptomes have potential to detect unruptured intracranial aneurysms Open
Our findings demonstrate the potential of machine-learning methods to classify IA cases and create predictive models for unruptured IAs using circulating neutrophil transcriptome data. Future studies are needed to replicate these findings …
View article: Outcome prediction of intracranial aneurysm treatment by flow diverters using machine learning
Outcome prediction of intracranial aneurysm treatment by flow diverters using machine learning Open
OBJECTIVE Flow diverters (FDs) are designed to occlude intracranial aneurysms (IAs) while preserving flow to essential arteries. Incomplete occlusion exposes patients to risks of thromboembolic complications and rupture. A priori assessmen…
View article: Computer-Assisted Three-Dimensional Morphology Evaluation of Intracranial Aneurysms
Computer-Assisted Three-Dimensional Morphology Evaluation of Intracranial Aneurysms Open
View article: Risk of Branch Occlusion and Ischemic Complications with the Pipeline Embolization Device in the Treatment of Posterior Circulation Aneurysms
Risk of Branch Occlusion and Ischemic Complications with the Pipeline Embolization Device in the Treatment of Posterior Circulation Aneurysms Open
There was a low occlusion incidence in end arteries following branch coverage at last follow-up. The incidence was higher in the posterior cerebral artery and vertebral artery where collateral supply is high. Branch occlusion was not assoc…
View article: Pipeline embolization of posterior circulation aneurysms: a multicenter study of 131 aneurysms
Pipeline embolization of posterior circulation aneurysms: a multicenter study of 131 aneurysms Open
OBJECTIVE Flow diversion for posterior circulation aneurysms performed using the Pipeline embolization device (PED) constitutes an increasingly common off-label use for otherwise untreatable aneurysms. The safety and efficacy of this treat…
View article: Predictors of Incomplete Occlusion following Pipeline Embolization of Intracranial Aneurysms: Is It Less Effective in Older Patients?
Predictors of Incomplete Occlusion following Pipeline Embolization of Intracranial Aneurysms: Is It Less Effective in Older Patients? Open
Complete occlusion following PED treatment of intracranial aneurysms can be influenced by several factors related to the patient, aneurysm, and treatment. Of these factors, older age (older than 70 years) and nonsmoking status were indepen…
View article: Congenital and infantile malignant melanoma of the scalp: A systematic review
Congenital and infantile malignant melanoma of the scalp: A systematic review Open
Congenital and infantile malignant melanomas are rare and typically carry poor prognosis. The purpose of this article was to review the data on congenital and infantile malignant melanomas of the scalp in order to understand its presentati…
View article: Treatment of Tandem Internal Carotid Artery Aneurysms Using a Single Pipeline Embolization Device: Evaluation of Safety and Efficacy
Treatment of Tandem Internal Carotid Artery Aneurysms Using a Single Pipeline Embolization Device: Evaluation of Safety and Efficacy Open
Tandem aneurysms of the ICA can be treated with a single Pipeline Embolization Device with high rates of complete occlusion. While there appeared to be a trend toward higher thromboembolic complication rates, this did not reach statistical…
View article: Use of Platelet Function Testing Before Pipeline Embolization Device Placement
Use of Platelet Function Testing Before Pipeline Embolization Device Placement Open
Background and Purpose— Thromboembolic complications constitute a significant source of morbidity after neurointerventional procedures. Flow diversion using the pipeline embolization device for the treatment of intracranial aneurysms neces…
View article: Management of acute ischemic stroke due to tandem occlusion: should endovascular recanalization of the extracranial or intracranial occlusive lesion be done first?
Management of acute ischemic stroke due to tandem occlusion: should endovascular recanalization of the extracranial or intracranial occlusive lesion be done first? Open
OBJECTIVE Acute tandem occlusions of the cervical internal carotid artery and an intracranial large vessel present treatment challenges. Controversy exists regarding which lesion should be addressed first. The authors sought to evaluate th…
View article: Computer-assisted adjuncts for aneurysmal morphologic assessment: toward more precise and accurate approaches
Computer-assisted adjuncts for aneurysmal morphologic assessment: toward more precise and accurate approaches Open
Neurosurgeons currently base most of their treatment decisions for intracranial aneurysms (IAs) on morphological measurements made manually from 2D angiographic images. These measurements tend to be inaccurate because 2D measurements canno…
View article: Noninvasive monitoring intracranial pressure – A review of available modalities
Noninvasive monitoring intracranial pressure – A review of available modalities Open
Although the intraventricular catheter remains the gold standard for monitoring ICP, several noninvasive modalities that can be used in settings when invasive monitoring is not possible are also available. In our opinion, measurement of op…
View article: Perioperative steroids for lumbar disc surgery: A meta-analysis of randomized controlled trials
Perioperative steroids for lumbar disc surgery: A meta-analysis of randomized controlled trials Open
Intraoperative epidural steroid administration offers some benefit in pain control with a significant reduction in the length of hospital stay. However, there is insufficient evidence to support the routine use of oral and intravenous ster…