Huzaifa Adamali
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View article: Comparing Approaches to Teaching Patients How to Use an App-Based Home Spirometer: Randomized Controlled Trial
Comparing Approaches to Teaching Patients How to Use an App-Based Home Spirometer: Randomized Controlled Trial Open
Background Bluetooth-enabled, app-based home spirometry has been validated for use in the diagnosis and monitoring of respiratory disease. Remote teaching (virtual or self-directed) of patients on how to use an app-based home spirometry of…
View article: Sotrovimab versus usual care in patients admitted to hospital with COVID-19 (RECOVERY): a randomised, controlled, open-label, platform trial
Sotrovimab versus usual care in patients admitted to hospital with COVID-19 (RECOVERY): a randomised, controlled, open-label, platform trial Open
UK Research and Innovation (Medical Research Council) and National Institute for Health and Care Research.
View article: Translation from english into Urdu of a clinical decision tool to screen older women with back pain for osteoporotic-related vertebral fragility fractures
Translation from english into Urdu of a clinical decision tool to screen older women with back pain for osteoporotic-related vertebral fragility fractures Open
View article: Molnupiravir or nirmatrelvir–ritonavir plus usual care versus usual care alone in patients admitted to hospital with COVID-19 (RECOVERY): a randomised, controlled, open-label, platform trial
Molnupiravir or nirmatrelvir–ritonavir plus usual care versus usual care alone in patients admitted to hospital with COVID-19 (RECOVERY): a randomised, controlled, open-label, platform trial Open
UK Research and Innovation (UK Medical Research Council), the National Institute for Health and Care Research, and the Wellcome Trust.
View article: Ramadan fasting for patients with chronic respiratory diseases: a systematic review and consensus recommendations for healthcare professionals
Ramadan fasting for patients with chronic respiratory diseases: a systematic review and consensus recommendations for healthcare professionals Open
Background Ramadan, observed by nearly 2 billion Muslims worldwide, involves fasting from dawn to sunset, which can present challenges for individuals with chronic respiratory diseases due to altered medication regimens and oral intake res…
View article: Higher dose corticosteroids in hospitalised COVID-19 patients requiring ventilatory support (RECOVERY): a randomised, controlled, open-label, platform trial
Higher dose corticosteroids in hospitalised COVID-19 patients requiring ventilatory support (RECOVERY): a randomised, controlled, open-label, platform trial Open
View article: Analysis of the representation of skin tone diversity amongst medical resources illustrating dermatological manifestations of dermatomyositis, systemic sclerosis and vasculitis
Analysis of the representation of skin tone diversity amongst medical resources illustrating dermatological manifestations of dermatomyositis, systemic sclerosis and vasculitis Open
Objectives Cutaneous manifestations of systemic autoimmune rheumatic disease–interstitial lung disease (SARD-ILD) are clinically useful diagnostic features that can support early diagnosis and management. However, medical education resourc…
View article: The impact of targeted local outreach clinics to improve COVID-19 vaccine uptake: controlled interrupted time series in South West England
The impact of targeted local outreach clinics to improve COVID-19 vaccine uptake: controlled interrupted time series in South West England Open
View article: Assessment of the impact of social deprivation, distance to hospital and time to diagnosis on survival in idiopathic pulmonary fibrosis
Assessment of the impact of social deprivation, distance to hospital and time to diagnosis on survival in idiopathic pulmonary fibrosis Open
View article: Identification of connective tissue disease autoantibodies and a novel autoantibody anti-annexin A11 in patients with “idiopathic” interstitial lung disease
Identification of connective tissue disease autoantibodies and a novel autoantibody anti-annexin A11 in patients with “idiopathic” interstitial lung disease Open
Specific guidance on autoantibody testing and interpretation in patients with ILD could improve diagnostic accuracy. Further work is required to determine the clinical significance of anti-annexin A11.
View article: Large-scale phenotyping of patients with long COVID post-hospitalization reveals mechanistic subtypes of disease
Large-scale phenotyping of patients with long COVID post-hospitalization reveals mechanistic subtypes of disease Open
One in ten severe acute respiratory syndrome coronavirus 2 infections result in prolonged symptoms termed long coronavirus disease (COVID), yet disease phenotypes and mechanisms are poorly understood 1 . Here we profiled 368 plasma protein…
View article: A Retrospective Analysis of 2-Year Follow-Up of Patients with Incidental Findings of Sarcoidosis
A Retrospective Analysis of 2-Year Follow-Up of Patients with Incidental Findings of Sarcoidosis Open
Introduction: Sarcoidosis is a multi-system granulomatous disease most commonly involving the lungs. It may be incidentally diagnosed during imaging studies for other conditions or non-specific symptoms. The appropriate follow-up of incide…
View article: Accelerated immune ageing is associated with COVID-19 disease severity
Accelerated immune ageing is associated with COVID-19 disease severity Open
View article: Real-world experience of nintedanib for progressive fibrosing interstitial lung disease in the UK
Real-world experience of nintedanib for progressive fibrosing interstitial lung disease in the UK Open
Background Nintedanib slows progression of lung function decline in patients with progressive fibrosing (PF) interstitial lung disease (ILD) and was recommended for this indication within the United Kingdom (UK) National Health Service in …
View article: Factoring patients' beliefs and values into decisions around anticoagulation: a community-led multi-cycle quality improvement project
Factoring patients' beliefs and values into decisions around anticoagulation: a community-led multi-cycle quality improvement project Open
Low-molecular-weight heparin (LMWH), prescribed for prophylaxis of venous thromboembolism, is derived from porcine animal products. An audit in our Trust showed that most healthcare professionals (95%, n=58/61) did not consider religious o…
View article: Animal-derived medicinal products: community representatives' views of their use
Animal-derived medicinal products: community representatives' views of their use Open
View article: Empagliflozin in patients admitted to hospital with COVID-19 (RECOVERY): a randomised, controlled, open-label, platform trial
Empagliflozin in patients admitted to hospital with COVID-19 (RECOVERY): a randomised, controlled, open-label, platform trial Open
For the Nepali, Hindi, Indonesian (Bahasa) and Vietnamese translations of the abstract see Supplementary Materials section.
View article: Long COVID research: an update from the PHOSP-COVID Scientific Summit
Long COVID research: an update from the PHOSP-COVID Scientific Summit Open
View article: The Impact of Integrated Palliative Care on Survival in Idiopathic Pulmonary Fibrosis: A Retrospective Multicenter Comparison
The Impact of Integrated Palliative Care on Survival in Idiopathic Pulmonary Fibrosis: A Retrospective Multicenter Comparison Open
Background: Early and integrated palliative care is recommended for patients with idiopathic pulmonary fibrosis. Unfortunately, palliative care delivery remains poor due to various barriers in practice. This study describes various palliat…
View article: Category ‐ Quality Improvement
Category ‐ Quality Improvement Open
Vitamin D Serum and HOMA-IR in Indonesian Post-Menopause
View article: Ziritaxestat, a Novel Autotaxin Inhibitor, and Lung Function in Idiopathic Pulmonary Fibrosis
Ziritaxestat, a Novel Autotaxin Inhibitor, and Lung Function in Idiopathic Pulmonary Fibrosis Open
Importance There is a major need for effective, well-tolerated treatments for idiopathic pulmonary fibrosis (IPF). Objective To assess the efficacy and safety of the autotaxin inhibitor ziritaxestat in patients with IPF. Design, Setting, a…
View article: Determinants of recovery from post-COVID-19 dyspnoea: analysis of UK prospective cohorts of hospitalised COVID-19 patients and community-based controls
Determinants of recovery from post-COVID-19 dyspnoea: analysis of UK prospective cohorts of hospitalised COVID-19 patients and community-based controls Open
View article: Higher dose corticosteroids in patients admitted to hospital with COVID-19 who are hypoxic but not requiring ventilatory support (RECOVERY): a randomised, controlled, open-label, platform trial
Higher dose corticosteroids in patients admitted to hospital with COVID-19 who are hypoxic but not requiring ventilatory support (RECOVERY): a randomised, controlled, open-label, platform trial Open
View article: Prevalence of physical frailty, including risk factors, up to 1 year after hospitalisation for COVID-19 in the UK: a multicentre, longitudinal cohort study
Prevalence of physical frailty, including risk factors, up to 1 year after hospitalisation for COVID-19 in the UK: a multicentre, longitudinal cohort study Open
View article: 89 The provision of culturally appropriate palliative care at a large teaching hospital in the UK
89 The provision of culturally appropriate palliative care at a large teaching hospital in the UK Open
Background Palliative care is a holistic approach aiming to improve quality of life of those with life-limiting illness and their caregivers. Care should be individualised in line with what is important to the patient/their family. To meet…
View article: Multi-center evaluation of baseline neutrophil-to-lymphocyte (NLR) ratio as an independent predictor of mortality and clinical risk stratifier in idiopathic pulmonary fibrosis
Multi-center evaluation of baseline neutrophil-to-lymphocyte (NLR) ratio as an independent predictor of mortality and clinical risk stratifier in idiopathic pulmonary fibrosis Open
Breathing Matters, GSK, CF Trust, BLF-Asthma, MRC, NIHR Alpha-1 Foundation.
View article: A multidisciplinary approach to the diagnosis of antisynthetase syndrome
A multidisciplinary approach to the diagnosis of antisynthetase syndrome Open
Antisynthetase syndrome is a subtype of idiopathic inflammatory myopathy, strongly associated with the presence of interstitial lung disease. Diagnosis is made by identifying myositis-specific antibodies directed against aminoacyl tRNA syn…
View article: Safety, tolerability, and efficacy of pirfenidone in patients with rheumatoid arthritis-associated interstitial lung disease: a randomised, double-blind, placebo-controlled, phase 2 study
Safety, tolerability, and efficacy of pirfenidone in patients with rheumatoid arthritis-associated interstitial lung disease: a randomised, double-blind, placebo-controlled, phase 2 study Open
Genentech.
View article: Baricitinib in patients admitted to hospital with COVID-19 (RECOVERY): a randomised, controlled, open-label, platform trial and updated meta-analysis
Baricitinib in patients admitted to hospital with COVID-19 (RECOVERY): a randomised, controlled, open-label, platform trial and updated meta-analysis Open
View article: Multi-center evaluation of baseline neutrophil:lymphocyte (NLR) ratio as an independent predictor of mortality and clinical risk stratifier in Idiopathic Pulmonary Fibrosis
Multi-center evaluation of baseline neutrophil:lymphocyte (NLR) ratio as an independent predictor of mortality and clinical risk stratifier in Idiopathic Pulmonary Fibrosis Open
Summary Background Idiopathic pulmonary fibrosis (IPF) is a progressive, fatal disorder with a variable disease trajectory. The aim of this study was to assess the potential of neutrophil-to-lymphocyte ratio (NLR) to predict outcomes for p…