Jichun Tan
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View article: Adipose tissue explant culture using PDMS flow chambers: an alternative to static explant culture
Adipose tissue explant culture using PDMS flow chambers: an alternative to static explant culture Open
As obesity rates continue to rise, it is important that we can effectively study adipose tissue to understand its physiological contribution in individuals with obesity. Unfortunately, due to the fragility and buoyancy of adipose tissue, c…
Thyroid autoimmunity is strongly associated with embryo quality in infertile euthyroid women receiving IVF/ICSI, especially patients with TSH values above 2.5 uIU/mL and poor ovarian response Open
This study provides comprehensive evidence for the adverse effects of TAI on embryo quality during IVF/ICSI. It is necessary to closely monitor the thyroid hormones and autoantibody levels during treatment, especially in TAI women with TSH…
Recent Advances in Efficient Spiking Neural Networks: Architectures, Learning Rules, and Hardware Realizations Open
Spiking Neural Networks (SNNs) have emerged as a promising paradigm for energy-efficient and event-driven computing, drawing inspiration from biological neurons. Recent research has introduced novel methods to enhance the performance, robu…
The effects of exercise frequency on sexual function and psychological health in infertile women Open
Background Infertility can adversely affect both sexual function and psychological well-being in women. Although physical activity is widely known to benefit overall health, its specific influence on the sexual and mental health of inferti…
Towards Efficient CNN Acceleration: A Review of Sparsity, Compression, and Emerging Hardware Architectures Open
The rising computational demands of convolutional neural networks (CNNs), especially in edge and real-time systems, have prompted extensive research into energy-efficient and high-throughput hardware accelerators. Recent innovations span a…
Comparative analysis of sexual function and psychological health in infertile patients with different ovarian dysfunctions Open
Background Premature ovarian insufficiency (POI) and polycystic ovary syndrome (PCOS) are common reproductive disorders that negatively affect women’s sexual and psychological health. Aim This study aims to compare sexual function and psyc…
Unraveling the Mechanism and Influence of Auxiliary Ligands on the Isomerization of Neutral [P,O]-Chelated Nickel Complexes for Olefin Polymerization Open
The copolymerization of ethylene with polar monomers presents a significant challenge. While palladium catalysts have shown promise, nickel catalysts are more economical but suffer from poor activity. Previous studies suggest that the isom…
View article: Preimplantation genetic testing for structural rearrangements by genome-wide SNP genotyping and haplotype analysis: a prospective multicenter clinical study
Preimplantation genetic testing for structural rearrangements by genome-wide SNP genotyping and haplotype analysis: a prospective multicenter clinical study Open
This study was funded by the National Key Research and Development Program of China (2022YFC2703200, 2021YFC2700600, 2021YFC2700500), National Natural Science Foundation of China (82201807, 82171639, 82071717). Shanghai Science and Technol…
View article: A scalable solution for precisely measuring low abundant neurobiomarkers from micro‐sampling
A scalable solution for precisely measuring low abundant neurobiomarkers from micro‐sampling Open
Background Cutting‐edge ultrasensitive immunoassay platforms have unveiled the potential of blood‐based biomarkers, offering detection at low fg/mL levels for early neurodegenerative disorder prognosis, screening, and therapeutic monitorin…
Non-invasive prediction of human embryonic ploidy using artificial intelligence: a systematic review and meta-analysis Open
This work was supported by the National Key R&D Program of China (2022YFC2702905), the Shengjing Freelance Researcher Plan of Shengjing Hospital and the 345 talent project of Shengjing Hospital.
View article: Prevalence and disparities in sexual and reproductive health of women of reproductive age (20–49 years) in China: A national cross-sectional study
Prevalence and disparities in sexual and reproductive health of women of reproductive age (20–49 years) in China: A national cross-sectional study Open
Women's SRH behaviours and experiences have evolved, along with shifts in the spectrums of gynaecological diseases and STDs in China. Urgent recalibration of health care policies and disease control strategies is necessary, aligning them w…
Effect of single blastocyst-stage versus single cleavage-stage embryo transfer on cumulative live births in women with good prognosis undergoing in vitro fertilization: Multicenter Randomized Controlled Trial Open
In this multicenter, non-inferiority, randomized trial, we randomly assigned 992 women undergoing in-vitro fertilization (IVF) with a good prognosis (aged 20-40, ≥3 transferrable cleavage-stage embryos) to strategies of blastocyst-stage (n…
Comparative Analysis of Sexual Function and Psychological Health in Infertile Patients with Different Ovarian Dysfunctions Open
Objective This study aims to evaluate and compare sexual function and psychological health among infertile patients with different ovarian dysfunctions, specifically polycystic ovary syndrome (PCOS), premature ovarian insufficiency (POI), …
View article: Fertility history and intentions of married women, China
Fertility history and intentions of married women, China Open
The willingness of Chinese married women to give birth remained low, even with relaxation of the one-child policy.
#222 : Exosomes Derived of Menstrual Blood Stem Cells Suppress IUA Endometrial Fibrosis Through P65-UBR4-YAP Pathway Open
Background and Aims: IUA is the second leading cause of secondary infertility in women, and it is urgent to find a new therapeutic method to achieve functional regeneration of endometrial. We previously found that menstrual blood stem cell…
#220 : PDGFBB Improved the Biological Function of Menstrual Blood-Derived Stromal Cells and the Anti-Fibrotic Properties of Exosomes Open
Background and Aims: Intrauterine adhesion (IUA) is a reproductive dysfunction disease characterized by endometrial fibrosis, with limited therapeutic options and poor prognosis. Our previous studies confirmed that menstrual blood-derived …
Exosomes derived from menstrual blood stromal cells ameliorated premature ovarian insufficiency and granulosa cell apoptosis by regulating SMAD3/AKT/MDM2/P53 pathway via delivery of thrombospondin-1 Open
Premature ovarian insufficiency (POI) is clinically irreversible and seriously damages female fertility. We previously demonstrated that menstrual blood stromal cells (MenSCs)-derived exosomes (EXOs) effectively improved ovarian functions …
Effect of Paternal Body Mass Index on <i>In Vitro</i> Fertilization and Neonatal Outcomes among Oligozoospermia and Asthenospermia Patients Open
Purpose: Male overweight and obesity could affect sperm quality and reproductive health. However, the impact of body mass index (BMI) on assisted reproductive technology (ART) outcomes in oligospermia and/or asthenospermia patients is yet …
O-214 interaction of air pollution and meteorological factors on IVF outcomes: a multicenter study in China Open
Study question Is there an interaction between air pollution and meteorological factors on IVF outcomes? Summary answer The correlation between air-pollutant exposure and IVF outcomes was modified by meteorological conditions, especially t…
View article: Interaction of air pollution and meteorological factors on IVF outcomes: A multicenter study in China
Interaction of air pollution and meteorological factors on IVF outcomes: A multicenter study in China Open
Our results suggested that the associations between air-pollutant exposure and IVF outcomes were modified by meteorological conditions, especially temperature and wind speed. Women undergoing IVF treatment should be advised to reduce outdo…
View article: Prednisone vs Placebo and Live Birth in Patients With Recurrent Implantation Failure Undergoing In Vitro Fertilization
Prednisone vs Placebo and Live Birth in Patients With Recurrent Implantation Failure Undergoing In Vitro Fertilization Open
Importance Implantation failure remains a critical barrier to in vitro fertilization. Prednisone, as an immune-regulatory agent, is widely used to improve the probability of implantation and pregnancy, although the evidence for efficacy is…