Hyogo Horiguchi
YOU?
Author Swipe
View article: Association between allergic rhinitis and work productivity in a non-clinical setting: a cross-sectional study
Association between allergic rhinitis and work productivity in a non-clinical setting: a cross-sectional study Open
Objective: Allergic rhinitis (AR) is a prevalent condition in Japan that negatively affects workers by reducing their productivity. However, previous studies primarily focused on patients with severe AR symptoms. This exploratory study aim…
View article: Effects of Environmental Cadmium Exposure Sufficient to Induce Renal Tubular Dysfunction on Bone Mineral Density Among Female Farmers in Cadmium-Polluted Areas in Northern Japan
Effects of Environmental Cadmium Exposure Sufficient to Induce Renal Tubular Dysfunction on Bone Mineral Density Among Female Farmers in Cadmium-Polluted Areas in Northern Japan Open
In the Japanese Multi-Centered Environmental Toxicant Study (JMETS) conducted in five areas across Japan, we demonstrated that bone mineral density (BMD) in female farmers without renal tubular dysfunction was not adversely affected by exp…
View article: Disturbance on drug efficacy of dapagliflozin, an SGLT2 inhibitor, in mice
Disturbance on drug efficacy of dapagliflozin, an SGLT2 inhibitor, in mice Open
This study aimed to investigate the efficacy of dapagliflozin administration time using light-dark cycle-disrupted mice. Five-week-old male C57BL/6J mice were fed a control diet or high-fat diet (HFD) for 8-weeks under a disrupted light-da…
View article: Antitumor Effects of <scp><i>Sasa veitchii</i></scp> Extract on Human Pancreatic Adenocarcinoma Cells
Antitumor Effects of <span><i>Sasa veitchii</i></span> Extract on Human Pancreatic Adenocarcinoma Cells Open
Aim Sasa veitchii (Carrière) Rehder extract (SE) is a traditional medicine that has been reported to have various effects, including antitumor effects. We previously demonstrated that SE exhibited antitumor effects against murine pancreati…
View article: Perfluorohexanoic Acid-Induced Inhibition of Human Palate Cell Proliferation Through Upregulation of <i>miR-374a-5p</i>
Perfluorohexanoic Acid-Induced Inhibition of Human Palate Cell Proliferation Through Upregulation of <i>miR-374a-5p</i> Open
Per- and poly fluoroalkyl substances (PFAS) pose serious health concerns worldwide. Although the use of classical PFAS, such as perfluorooctane sulfonic acid (PFOS) and perfluorooctanoic acid (PFOA), is regulated, the toxicological effects…
View article: Sasa veitchii Extract Mitigates Mycophenolate Mofetil-Induced Human Palatal Cell Proliferation Inhibition by Downregulating microRNA-4680-3p
Sasa veitchii Extract Mitigates Mycophenolate Mofetil-Induced Human Palatal Cell Proliferation Inhibition by Downregulating microRNA-4680-3p Open
Cleft palate is a common birth defect worldwide and is caused by both genetic and environmental factors. Intrauterine drug exposure is one of the environmental factors that can induce cleft palate. Mycophenolate mofetil (MPM) is an immunos…
View article: Sasa veitchii Extract Mitigates Mycophenolate Mofetil-Induced Human Palatal Cell Proliferation Inhibition by Downregulating microRNA-4680-3p
Sasa veitchii Extract Mitigates Mycophenolate Mofetil-Induced Human Palatal Cell Proliferation Inhibition by Downregulating microRNA-4680-3p Open
(1) Cleft palate is a common birth defect worldwide and is caused by both genetic and environmental factors. Intrauterine drug exposure is one of the environmental factors that can induce cleft palate. Mycophenolate mofetil (MPM) is an imm…
View article: A suspected case of “itai-itai disease” in a cadmium-polluted area in Akita prefecture, Japan
A suspected case of “itai-itai disease” in a cadmium-polluted area in Akita prefecture, Japan Open
This is the first case of "itai-itai disease" in a Cd-polluted area in Akita prefecture.
View article: Relationship between personal-sampled air lead and blood lead in low-lead-exposure workers in Japan to apply multiple regression models determining permissible air lead concentration
Relationship between personal-sampled air lead and blood lead in low-lead-exposure workers in Japan to apply multiple regression models determining permissible air lead concentration Open
Objectives We investigated the relationship between lead in air (Pb-A) measured by personal sampling and blood lead (Pb-B) in workers with relatively low lead exposure to estimate the permissible air concentration of lead corresponding to …
View article: Occupational exposure limits for acetaldehyde, 2-bromopropane, glyphosate, manganese and inorganic manganese compounds, and zinc oxide nanoparticle, and the biological exposure indices for cadmium and cadmium compounds and ethylbenzene, and carcinogenicity, occupational sensitizer, and reproductive toxicant classifications
Occupational exposure limits for acetaldehyde, 2-bromopropane, glyphosate, manganese and inorganic manganese compounds, and zinc oxide nanoparticle, and the biological exposure indices for cadmium and cadmium compounds and ethylbenzene, and carcinogenicity, occupational sensitizer, and reproductive toxicant classifications Open
Group 1 is proposed as the respiratory and skin occupational sensitizer classifications for ortho-phthalaldehyde. Group 2 is proposed as the skin occupational sensitizer classification for ethylene glycol dimethacrylate and 1,6-hexanediol …
View article: Reassessment of the threshold of the blood lead level to increase urinary δ-aminolevulinic acid based on their relationship in recent lead workers in Japan
Reassessment of the threshold of the blood lead level to increase urinary δ-aminolevulinic acid based on their relationship in recent lead workers in Japan Open
Objectives The present study investigated the quantitative relationship between blood lead (Pb-B) and urinary δ⁻aminolevulinic acid (ALA-U) in lead workers, and examined the Pb-B level that induces increases in ALA-U and the corresponding …
View article: Exposure Assessment of Cadmium in Female Farmers in Cadmium-Polluted Areas in Northern Japan
Exposure Assessment of Cadmium in Female Farmers in Cadmium-Polluted Areas in Northern Japan Open
Akita prefecture is located in the northern part of Japan and has many cadmium-polluted areas. We herein performed an exposure assessment of cadmium in 712 and 432 female farmers in two adjacent cadmium-polluted areas (A and B, respectivel…