Hyukmin Lee
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View article: Increasing Antimicrobial Resistance Profile Diversity of Colonizing Group B <i>Streptococcus</i> in Reproductive-aged Women in Korea
Increasing Antimicrobial Resistance Profile Diversity of Colonizing Group B <i>Streptococcus</i> in Reproductive-aged Women in Korea Open
The acquisition of diverse resistance genes has expanded AMR profiles in colonized GBS, emphasizing the need for sustained nationwide surveillance.
View article: Genetic and clinical distinction between aggressive NK-cell leukemia and extranodal NK/T-cell lymphoma with bone marrow involvement
Genetic and clinical distinction between aggressive NK-cell leukemia and extranodal NK/T-cell lymphoma with bone marrow involvement Open
Aggressive NK-cell leukemia (ANKL) shares common clinicopathological features with extranodal NK/T-cell lymphoma with bone marrow (BM) involvement (ENKTL-BM), making their distinction challenging in BM examination. Despite numerous studies…
View article: RAT DISSECTION ALTERNATIVES IN MALAYSIAN BIOLOGY EDUCATION: A NEED ANALYSIS
RAT DISSECTION ALTERNATIVES IN MALAYSIAN BIOLOGY EDUCATION: A NEED ANALYSIS Open
In rat dissection, students are found to be weak and unable to identify anatomical organs and draw and label them effectively in visual literacy. Since rat dissection is part of the Malaysian standardised curriculum, it must be preferred d…
View article: Prognostic Landscape of <i>TP53</i> Mutations in Hematologic Malignancies
Prognostic Landscape of <i>TP53</i> Mutations in Hematologic Malignancies Open
Our findings highlight VAF and RFS as valuable tools for stratifying TP53-mutant patients into high-risk and low-risk groups.
View article: <i>In-vitro</i> Activities of Zoliflodacin and Solithromycin Against <i>Neisseria gonorrhoeae</i> Isolates from Korea
<i>In-vitro</i> Activities of Zoliflodacin and Solithromycin Against <i>Neisseria gonorrhoeae</i> Isolates from Korea Open
Novel antimicrobial agents are continually developed to address the global threat of multidrug-resistant Neisseria gonorrhoeae. Promising candidates include zoliflodacin and, possibly, solithromycin. We evaluated their in-vitro
View article: Genetic and Clinical Distinction between Aggressive NK-cell Leukemia and Extranodal NK/T-cell Lymphoma with Bone Marrow Involvement
Genetic and Clinical Distinction between Aggressive NK-cell Leukemia and Extranodal NK/T-cell Lymphoma with Bone Marrow Involvement Open
Aggressive NK-cell leukemia (ANKL) shares common clinicopathological features with extranodal NK/T-cell lymphoma with bone marrow (BM) involvement (ENKTL-BM), making their distinction challenging in BM examination. Despite numerous studies…
View article: Mock communities to assess biases in next-generation sequencing of bacterial species representation
Mock communities to assess biases in next-generation sequencing of bacterial species representation Open
Background: The 16S rRNA-targeted next-generation sequencing (NGS) has been widely used as the primary tool for microbiome analysis. However, whether the sequenced microbial diversity absolutely represents the original sample composition r…
View article: A head-to-head comparison of five MALDI-TOF mass spectrometry systems for detection of clinically relevant bacteria and fungi, a single center study
A head-to-head comparison of five MALDI-TOF mass spectrometry systems for detection of clinically relevant bacteria and fungi, a single center study Open
We compared the accuracy of five MALDI-TOF MS, Bruker Biotyper, Biotyper Sirius, bioMérieux VITEK MS, VITEK MS Prime, and ASTA MicroIDSys for the identification of bacteria and fungi that are commonly isolated in clinical microbiology labo…
View article: Development of a wastewater based infectious disease surveillance research system in South Korea
Development of a wastewater based infectious disease surveillance research system in South Korea Open
View article: Evaluation of the Disk Diffusion Test for <i>Bacteroides fragilis</i> Group Clinical Isolates
Evaluation of the Disk Diffusion Test for <i>Bacteroides fragilis</i> Group Clinical Isolates Open
The DDT can be a useful alternative antimicrobial susceptibility test for BFG isolates when using the ATU zone to reduce errors.
View article: <i>Pasteurella</i> Infections in South Korea and Systematic Review and Meta-analysis of <i>Pasteurella</i> Bacteremia
<i>Pasteurella</i> Infections in South Korea and Systematic Review and Meta-analysis of <i>Pasteurella</i> Bacteremia Open
Pasteurella spp. can cause fatal zoonotic infections in humans. We performed a multicenter study to investigate the prevalence and clinical features of Pasteurella infections in South Korea during 2018‒2022. We also conducted a collaborati…
View article: Nosocomial transmission of fluconazole-resistant <i>Candida glabrata</i> bloodstream isolates revealed by whole-genome sequencing
Nosocomial transmission of fluconazole-resistant <i>Candida glabrata</i> bloodstream isolates revealed by whole-genome sequencing Open
The clonal transmission of fluconazole-resistant Candida glabrata isolates within hospitals has seldom been analyzed by whole-genome sequencing (WGS). We performed WGS on 79 C . glabrata isolates, comprising 31 isolates from three prematur…
View article: Prevalence and Molecular Characterization of Pharyngeal Gonorrhea in Korean Men With Urethritis
Prevalence and Molecular Characterization of Pharyngeal Gonorrhea in Korean Men With Urethritis Open
The prevalence of pharyngeal gonorrhea in Korean men with gonococcal urethritis is as high as 30.5%, highlighting the need for pharyngeal screening in high-risk groups. Ceftriaxone is the recommended treatment for pharyngeal gonorrhea.
View article: Role of Clinical Microbiology Laboratory in Healthcare-associated Infection Prevention and Control
Role of Clinical Microbiology Laboratory in Healthcare-associated Infection Prevention and Control Open
View article: Identifying Contact Time Required for Secondary Transmission of<i>Clostridioides difficile</i>Infections by Using Real-Time Locating System
Identifying Contact Time Required for Secondary Transmission of<i>Clostridioides difficile</i>Infections by Using Real-Time Locating System Open
Considering patient room shortages and prevalence of other communicable diseases, reassessing the isolation of patients with Clostridioides difficile infection (CDI) is imperative. We conducted a retrospective study to investigate the seco…
View article: Development of a multiplex droplet digital PCR method for detection and monitoring of Mycobacterium tuberculosis and drug-resistant tuberculosis
Development of a multiplex droplet digital PCR method for detection and monitoring of Mycobacterium tuberculosis and drug-resistant tuberculosis Open
View article: First Case of Spontaneous Bacterial Peritonitis Caused by <i>Enterococcus pallens</i> in Korea
First Case of Spontaneous Bacterial Peritonitis Caused by <i>Enterococcus pallens</i> in Korea Open
Cheol O Bae, M.D., Dahee Jeong, M.T., Jin Woo Park, M.T., Yoon Hee Lee, B.S., Jinho Lee, M.D., Seo Wan Kim, M.D., Ki Ho Hong, M.D., Hyukmin Lee, M.D., Dongeun Yong, M.D.. Lab Med Online 2024;14:137-41. https://doi.org/10.47429/lmo.2024.14.…
View article: Carbapenem-resistant <i>Acinetobacter baumannii</i> Outbreak in a COVID-19 Isolation Ward and Successful Outbreak Control with Infection Control Measures
Carbapenem-resistant <i>Acinetobacter baumannii</i> Outbreak in a COVID-19 Isolation Ward and Successful Outbreak Control with Infection Control Measures Open
In addition to applying PPE and COVID-19 precautions in COVID-19 isolation wards, adhering to strict contact precautions along with environmental control can help prevent the spread of multidrug-resistant bacteria.
View article: Analysis of the Correlation between the Concentration of Pathogen Nucleic Acids in Wastewater and Disease Incidence: A Surveillance Study of Wastewater-Based Infectious Diseases
Analysis of the Correlation between the Concentration of Pathogen Nucleic Acids in Wastewater and Disease Incidence: A Surveillance Study of Wastewater-Based Infectious Diseases Open
View article: 2023 Korean Association of Urogenital Tract Infection and Inflammation guidelines for gonococcal infection
2023 Korean Association of Urogenital Tract Infection and Inflammation guidelines for gonococcal infection Open
The incidence of gonorrhea has increased significantly in recent years in the United States, especially among sexually active twenty-year-olds. Although the incidence of gonorrhea has decreased in Korea since the early 2000s, it is still c…
View article: Parabacteroides leei sp. nov., isolated from human blood
Parabacteroides leei sp. nov., isolated from human blood Open
An obligate anaerobic, Gram-negative, rod-shaped and non-spore-forming bacterium, designated as strain GYB001 T , was isolated from the blood of a patient with a sigmoid colon perforation. Taxonomic characterization of the novel isolate wa…
View article: Korea Seroprevalence Study of Monitoring of SARS-COV-2 Antibody Retention and Transmission (K-SEROSMART): findings from national representative sample
Korea Seroprevalence Study of Monitoring of SARS-COV-2 Antibody Retention and Transmission (K-SEROSMART): findings from national representative sample Open
OBJECTIVES: We estimated the population prevalence of antibodies to severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2), including unreported infections, through a Korea Seroprevalence Study of Monitoring of SARS-CoV-2 Antibody Re…
View article: Detection and Characterization of Two Phenotypes of Candida parapsilosis in South Korea: Clinical Features and Microbiological Findings
Detection and Characterization of Two Phenotypes of Candida parapsilosis in South Korea: Clinical Features and Microbiological Findings Open
We believe that this is the first study describe the microbiological and molecular characteristics of bloodstream isolates of C. parapsilosis in Korea exhibiting two phenotypes (sinking and floating). An important aspect of our findings is…
View article: European Committee on Antimicrobial Susceptibility Testing-Recommended Rapid Antimicrobial Susceptibility Testing of <i>Escherichia coli</i>, <i>Klebsiella pneumoniae</i>, and <i>Staphylococcus aureus</i> From Positive Blood Culture Bottles
European Committee on Antimicrobial Susceptibility Testing-Recommended Rapid Antimicrobial Susceptibility Testing of <i>Escherichia coli</i>, <i>Klebsiella pneumoniae</i>, and <i>Staphylococcus aureus</i> From Positive Blood Culture Bottles Open
EUCAST-RAST for K. pneumoniae and S. aureus met the United States Food and Drug Administration criteria at 6 and 4 hours, respectively, whereas that for E. coli did not meet the criteria for up to 8 hours. RAST can sho…
View article: Tenosynovitis of the Hand Caused by <i>Kosakonia cowanii</i> After Being Pricked by a Beanstalk
Tenosynovitis of the Hand Caused by <i>Kosakonia cowanii</i> After Being Pricked by a Beanstalk Open
A 77-year-old man with pain in his left hand after being pricked by a beanstalk visited an emergency center. Symptoms and laboratory findings suggested infectious tenosynovitis. Using the Bruker Biotyper (Bruker Daltonics, Germany), Kosako…
View article: Performance Evaluation of QMAC-dRAST Using Consecutive Positive Clinical Blood Culture Samples
Performance Evaluation of QMAC-dRAST Using Consecutive Positive Clinical Blood Culture Samples Open
Background: Bacteremia is life-threatening to patients, with a case fatality rate of 30–40%. The QMAC-dRAST system (QuantaMatrix, Republic of Korea), which is based on time-lapse imaging technology, can generate antimicrobial susceptibilit…
View article: Fusobacterium nucleatum induces a tumor microenvironment with diminished adaptive immunity against colorectal cancers
Fusobacterium nucleatum induces a tumor microenvironment with diminished adaptive immunity against colorectal cancers Open
Background & Aims Fusobacterium nucleatum (FN) plays a pivotal role in the development and progression of colorectal cancer by modulating antitumor immune responses. However, the impact of FN on immune regulation in the tumor microenvi…
View article: Core Elements for Implementing Antimicrobial Stewardship Programs in Korean General Hospitals
Core Elements for Implementing Antimicrobial Stewardship Programs in Korean General Hospitals Open
Currently, antimicrobial resistance (AMR) is a major threat to global public health. To overcome this crisis, antimicrobial stewardship programs (ASPs) have been proposed. An ASP supports the optimal use of antimicrobials, including approp…
View article: Risk factors and microbiological features of recurrent Escherichia coli bloodstream infections
Risk factors and microbiological features of recurrent Escherichia coli bloodstream infections Open
Understanding the risk factors and microbiological features in recurrent Escherichia coli BSI is helpful for clinicians. Data of patients with E . coil BSI from 2017 to 2018 were collected. Antimicrobial resistance rates of E . coli were d…
View article: Developing Core Elements and Checklist Items for Implementing Antimicrobial Stewardship Programs in Korean General Hospitals: A Modified Delphi Survey
Developing Core Elements and Checklist Items for Implementing Antimicrobial Stewardship Programs in Korean General Hospitals: A Modified Delphi Survey Open
This Delphi survey provides useful indicators for the implementation of ASP in Korea and suggests national policy improvement about the barriers (e.g., shortage of staffing and financial support) existing in Korea for optimal implem…