Dong Hoon Shin
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View article: Correction: Proteogenomic characterization of molecular and cellular targets for treatment‑resistant subtypes in locally advanced cervical cancers
Correction: Proteogenomic characterization of molecular and cellular targets for treatment‑resistant subtypes in locally advanced cervical cancers Open
View article: Possible therapeutic trepanation on a frontal sinus of a skull from the Old Kingdom period of Egypt
Possible therapeutic trepanation on a frontal sinus of a skull from the Old Kingdom period of Egypt Open
Trepanation has been reported on skulls from major ancient civilizations since the Neolithic period. In this study, on a skull excavated from the Qau village site during the Old Kingdom period of ancient Egypt (7th to 8th dynasties; 2181-2…
View article: Correction: Proteogenomic characterization of molecular and cellular targets for treatment‑resistant subtypes in locally advanced cervical cancers
Correction: Proteogenomic characterization of molecular and cellular targets for treatment‑resistant subtypes in locally advanced cervical cancers Open
View article: Life Expectancy of the Tokugawa Shogun Family Estimated from Edo Period Historical Records
Life Expectancy of the Tokugawa Shogun Family Estimated from Edo Period Historical Records Open
Background: This study aims to estimate the average life expectancy of the Tokugawa Shogun family by analyzing historical documents. The data is also compared to modern Japanese life expectancy figures.Methods: The lifespan of members of t…
View article: Blood pressure management based on infarct volume after successful endovascular thrombectomy
Blood pressure management based on infarct volume after successful endovascular thrombectomy Open
Introduction: While the efficacy of endovascular thrombectomy (EVT) in large core infarcts has been established, the influence of blood pressure (BP) management on functional outcomes based on infarct volume remains unclear. Patients and m…
View article: Mediation of Time‐Related Blood Pressure Variability on Intensive Blood Pressure Lowering and Functional Outcomes Post Endovascular Therapy: A Post Hoc Analysis of the OPTIMAL‐BP Trial
Mediation of Time‐Related Blood Pressure Variability on Intensive Blood Pressure Lowering and Functional Outcomes Post Endovascular Therapy: A Post Hoc Analysis of the OPTIMAL‐BP Trial Open
Background We investigated whether the association between blood pressure (BP) management in patients with successful reperfusion following endovascular therapy (EVT) and functional outcomes is mediated by BP variability parameters. Method…
View article: Proteogenomic characterization of molecular and cellular targets for treatment-resistant subtypes in locally advanced cervical cancers
Proteogenomic characterization of molecular and cellular targets for treatment-resistant subtypes in locally advanced cervical cancers Open
View article: Forensic Anthropological Analysis of the Korean Empire’s Post-mortem Examination Report on Park Bong-Un of Unbong County
Forensic Anthropological Analysis of the Korean Empire’s Post-mortem Examination Report on Park Bong-Un of Unbong County Open
During the Joseon Dynasty of Korea, a reasonable investigation of the dead was well developed even before the introduction of modern forensic techniques from Western countries. Various reviews have been attempted on those investigation rec…
View article: Cost-effectiveness and other considerations for different research techniques applied in ancient DNA analysis
Cost-effectiveness and other considerations for different research techniques applied in ancient DNA analysis Open
Ancient DNA (aDNA) analysis has developed rapidly since it first emerged in the 1980s, becoming an almost indispensable tool in anthropological and archaeological sciences. Earlier aDNA study was based on the polymerase chain reaction (PCR…
View article: Effectiveness and satisfaction with virtual and donor dissections: A randomized controlled trial
Effectiveness and satisfaction with virtual and donor dissections: A randomized controlled trial Open
View article: Perspectives of Medical Students and Developers Regarding Virtual Reality, Augmented Reality, Mixed Reality, and 3D Printing Technologies: Survey Study
Perspectives of Medical Students and Developers Regarding Virtual Reality, Augmented Reality, Mixed Reality, and 3D Printing Technologies: Survey Study Open
Background Emerging technologies, such as virtual reality (VR), augmented reality (AR), mixed reality (MR), and 3D printing (3DP), have transformative potential in education and health care. However, complete integration has not yet been a…
View article: Effectiveness and Satisfaction of Virtual Dissection on Medical Students: Randomized Controlled Trials Compared to Cadaver Dissection
Effectiveness and Satisfaction of Virtual Dissection on Medical Students: Randomized Controlled Trials Compared to Cadaver Dissection Open
Recent technological advancements have revolutionized medical education, leading to a decline in traditional cadaver dissection. This study aims to investigate the academic performance and satisfaction of students by comparing the effectiv…
View article: Functional Outcomes Associated With Blood Pressure Decrease After Endovascular Thrombectomy
Functional Outcomes Associated With Blood Pressure Decrease After Endovascular Thrombectomy Open
Importance The associations between blood pressure (BP) decreases induced by medication and functional outcomes in patients with successful endovascular thrombectomy remain uncertain. Objective To evaluate whether BP reductions induced by …
View article: Archaeological and Anthropological Study on the Grave of Eunuch-Official Couple Serving for a Royal Court of Joseon Kingdom
Archaeological and Anthropological Study on the Grave of Eunuch-Official Couple Serving for a Royal Court of Joseon Kingdom Open
This article presents the findings of the study of a co-burial of a eunuch-official and his wife, found in the city of Uijeongbu, Gyeonggi-do Province, made in accordance with Confucian traditions during the Joseon Dynasty period. A descri…
View article: Development of a Novel Biomarker for the Progression of Idiopathic Pulmonary Fibrosis
Development of a Novel Biomarker for the Progression of Idiopathic Pulmonary Fibrosis Open
The progression of idiopathic pulmonary fibrosis (IPF) is diverse and unpredictable. We identified and validated a new biomarker for IPF progression. To identify a candidate gene to predict progression, we assessed differentially expressed…
View article: Paleoparasitology research on ancient helminth eggs and larvae in the Republic of Korea
Paleoparasitology research on ancient helminth eggs and larvae in the Republic of Korea Open
Paleoparasitology is a discipline that applies existing conventional and molecular techniques to study parasites found in ancient ruins. This review focuses on the history of the discovery of parasites (mostly helminth eggs and larvae) in …
View article: Perspectives of Medical Students and Developers Regarding Virtual Reality, Augmented Reality, Mixed Reality, and 3D Printing Technologies: Survey Study (Preprint)
Perspectives of Medical Students and Developers Regarding Virtual Reality, Augmented Reality, Mixed Reality, and 3D Printing Technologies: Survey Study (Preprint) Open
BACKGROUND Emerging technologies, such as virtual reality (VR), augmented reality (AR), mixed reality (MR), and 3D printing (3DP), have transformative potential in education and health care. However, complete integration has not yet been …
View article: Difference in linear enamel hypoplasia frequency between the 16<sup>th</sup>- to 19<sup>th</sup>-century agrarian populations of the Korean Joseon dynasty and Siberian Russia
Difference in linear enamel hypoplasia frequency between the 16<sup>th</sup>- to 19<sup>th</sup>-century agrarian populations of the Korean Joseon dynasty and Siberian Russia Open
We studied linear enamel hypoplasia (LEH) in cranial series representative of Eurasian farmers with divergent lifestyles and natural environments: Siberian Russian settlers and Joseon dynasty people. The teeth of Siberian settlers and Jo…
View article: Anthropological report of arctic people’s mummy found at a medieval grave of West Siberia
Anthropological report of arctic people’s mummy found at a medieval grave of West Siberia Open
In arctic zone of West Siberia, native people's bodies were sometimes mummified inside the medieval graves. In 2013 to 2017, we conducted the excavations of medieval graves at Zeleny Yar cemetery in Yamalo-Nenets Autonomous Okrug. Among th…
View article: A parasitological study on the possible toilet ruins of the Japanese colonial period in Korea
A parasitological study on the possible toilet ruins of the Japanese colonial period in Korea Open
In the past decade, experts have conducted parasitological research on archaeological specimens in Korea to collect historical parasite infection data. In these studies, parasitologists successfully described the infection pattern of each …
View article: Figure S7 from Dual Targeting of ERBB2/ERBB3 for the Treatment of SLC3A2-NRG1–Mediated Lung Cancer
Figure S7 from Dual Targeting of ERBB2/ERBB3 for the Treatment of SLC3A2-NRG1–Mediated Lung Cancer Open
The lungs of nude mice (8 weeks) were infected with adenovirus expressing E.V. or Flag-S-N gene (3x1011 PFU) through intratracheal injection once per two weeks for 2 months and then checked lung morphology and confirm plasmid infection thr…
View article: Data from Akt/mTOR Counteract the Antitumor Activities of Cixutumumab, an Anti-Insulin–like Growth Factor I Receptor Monoclonal Antibody
Data from Akt/mTOR Counteract the Antitumor Activities of Cixutumumab, an Anti-Insulin–like Growth Factor I Receptor Monoclonal Antibody Open
Recent reports have shown limited anticancer therapeutic efficacy of insulin-like growth factor receptor (IGF-1R)-targeted monoclonal antibodies (mAb), but the resistance mechanisms have not been completely identified. Because cooperation …
View article: Figure S7 from Dual Targeting of ERBB2/ERBB3 for the Treatment of SLC3A2-NRG1–Mediated Lung Cancer
Figure S7 from Dual Targeting of ERBB2/ERBB3 for the Treatment of SLC3A2-NRG1–Mediated Lung Cancer Open
The lungs of nude mice (8 weeks) were infected with adenovirus expressing E.V. or Flag-S-N gene (3x1011 PFU) through intratracheal injection once per two weeks for 2 months and then checked lung morphology and confirm plasmid infection thr…
View article: Data from Akt/mTOR Counteract the Antitumor Activities of Cixutumumab, an Anti-Insulin–like Growth Factor I Receptor Monoclonal Antibody
Data from Akt/mTOR Counteract the Antitumor Activities of Cixutumumab, an Anti-Insulin–like Growth Factor I Receptor Monoclonal Antibody Open
Recent reports have shown limited anticancer therapeutic efficacy of insulin-like growth factor receptor (IGF-1R)-targeted monoclonal antibodies (mAb), but the resistance mechanisms have not been completely identified. Because cooperation …
View article: Figure S3 from Dual Targeting of ERBB2/ERBB3 for the Treatment of SLC3A2-NRG1–Mediated Lung Cancer
Figure S3 from Dual Targeting of ERBB2/ERBB3 for the Treatment of SLC3A2-NRG1–Mediated Lung Cancer Open
Appearance of the tumors at the time of sacrifice.
View article: Supplementary Tables 1-2, Figures 1-6 from Akt/mTOR Counteract the Antitumor Activities of Cixutumumab, an Anti-Insulin–like Growth Factor I Receptor Monoclonal Antibody
Supplementary Tables 1-2, Figures 1-6 from Akt/mTOR Counteract the Antitumor Activities of Cixutumumab, an Anti-Insulin–like Growth Factor I Receptor Monoclonal Antibody Open
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View article: Figure S5 from Dual Targeting of ERBB2/ERBB3 for the Treatment of SLC3A2-NRG1–Mediated Lung Cancer
Figure S5 from Dual Targeting of ERBB2/ERBB3 for the Treatment of SLC3A2-NRG1–Mediated Lung Cancer Open
Mouse weight was measured on the final day of the experiment. The weight was not significantly different among groups. Student''s t test, average {plus minus} SEM; n=4~7, *, p<0.05.
View article: Figure S6 from Dual Targeting of ERBB2/ERBB3 for the Treatment of SLC3A2-NRG1–Mediated Lung Cancer
Figure S6 from Dual Targeting of ERBB2/ERBB3 for the Treatment of SLC3A2-NRG1–Mediated Lung Cancer Open
Human normal lung cells, BEAS-2B and CCD18-Lu were transfected with E.V. and Flag S-N gene (3 ï�g/ï�l) 2 times per week for 2 weeks and then compared morphologic changes between E.V. and SLC3A2-NRG1 fusion gene and plasmid expression eva…
View article: Figure S1 from Dual Targeting of ERBB2/ERBB3 for the Treatment of SLC3A2-NRG1–Mediated Lung Cancer
Figure S1 from Dual Targeting of ERBB2/ERBB3 for the Treatment of SLC3A2-NRG1–Mediated Lung Cancer Open
Serum-free media from HEK293T cells transfected with E.V. vector or SLC3A2-NRG1 fusion genes were coated onto 96-well microtiter plates at 10 ï�g/ml. HEK293T cells transfected with ERBB3 and ERBB4 were seeded, treatment with lapatinib dos…
View article: Figure S6 from Dual Targeting of ERBB2/ERBB3 for the Treatment of SLC3A2-NRG1–Mediated Lung Cancer
Figure S6 from Dual Targeting of ERBB2/ERBB3 for the Treatment of SLC3A2-NRG1–Mediated Lung Cancer Open
Human normal lung cells, BEAS-2B and CCD18-Lu were transfected with E.V. and Flag S-N gene (3 ï�g/ï�l) 2 times per week for 2 weeks and then compared morphologic changes between E.V. and SLC3A2-NRG1 fusion gene and plasmid expression eva…